| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.272376 |
| POTEF | POTE ankyrin domain family, member F | 0.162541 |
| NDRG1 | N-myc downstream regulated 1 | 0.146987 |
| ACTG1 | actin gamma 1 | 0.146229 |
| FNDC3B | fibronectin type III domain containing 3B | 0.135372 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.11682 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.104895 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.102801 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.101299 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0913732 |
| ASPH | aspartate beta-hydroxylase | 0.0889033 |
| GRB10 | growth factor receptor-bound protein 10 | 0.081641 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0788452 |
| FAM13A | family with sequence similarity 13, member A | 0.0778653 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0766748 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0738131 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0735419 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0667829 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0636427 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0625522 |
| TOP1 | topoisomerase (DNA) I | 0.062292 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0602832 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0586441 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0583735 |
| HMGA1 | high mobility group AT-hook 1 | 0.0582528 |
| RNF145 | ring finger protein 145 | 0.0570575 |
| SDC4 | syndecan 4 | 0.0568285 |
| ZNF292 | zinc finger protein 292 | 0.0560142 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0554519 |
| GOLGA4 | golgin A4 | 0.0553271 |
| PTK2 | protein tyrosine kinase 2 | 0.0545978 |
| TFG | TRK-fused gene | 0.0531017 |
| MSN | moesin | 0.0528868 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0528203 |
| LAMB3 | laminin, beta 3 | 0.0526874 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0523612 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0518307 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0516038 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0508782 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0506871 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0484845 |
| DSTN | destrin (actin depolymerizing factor) | 0.0473916 |
| RLF | rearranged L-myc fusion | 0.0472053 |
| PGK1 | phosphoglycerate kinase 1 | 0.0464777 |
| RASA2 | RAS p21 protein activator 2 | 0.0464544 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0462105 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0461363 |
| CCNL1 | cyclin L1 | 0.0458772 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0453735 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0451443 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0449708 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0445577 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0442275 |
| ANXA2 | annexin A2 | 0.0440983 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0437561 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0432737 |
| SETD5 | SET domain containing 5 | 0.0426855 |
| FLNB | filamin B, beta | 0.0426782 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0411578 |
| RCOR1 | REST corepressor 1 | 0.0409056 |
| RPL11 | ribosomal protein L11 | 0.0408002 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0397757 |
| USP3 | ubiquitin specific peptidase 3 | 0.0395041 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0389744 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0386015 |
| MXD1 | MAX dimerization protein 1 | 0.0375636 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0371695 |
| TMF1 | TATA element modulatory factor 1 | 0.0363117 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0359599 |
| EZR | ezrin | 0.0359246 |
| RUNX1 | runt-related transcription factor 1 | 0.0359123 |
| COPA | coatomer protein complex, subunit alpha | 0.0358684 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0357311 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0356719 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0353117 |
| CD2AP | CD2-associated protein | 0.0349231 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0347548 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0345345 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0341168 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0340059 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0339116 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0338418 |
| SLMAP | sarcolemma associated protein | 0.0337512 |
| FAM3C | family with sequence similarity 3, member C | 0.0335576 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0335529 |
| DTNA | dystrobrevin, alpha | 0.0335503 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0333134 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0330995 |
| CDC73 | cell division cycle 73 | 0.0330533 |
| CTSB | cathepsin B | 0.0329878 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0329721 |
| LDHA | lactate dehydrogenase A | 0.0329679 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.032935 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0329033 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0325785 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0325157 |
| NPTN | neuroplastin | 0.0322348 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0321843 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0320622 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0319749 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.0967848 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0906111 |
| TMSB10 | thymosin beta 10 | -0.0793888 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0767553 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0680698 |
| AHNAK | AHNAK nucleoprotein | -0.0659778 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0514894 |
| PTMA | prothymosin, alpha | -0.0486562 |
| FTL | ferritin, light polypeptide | -0.0480979 |
| RPS27A | ribosomal protein S27a | -0.0478615 |
| RNF213 | ring finger protein 213 | -0.0440705 |
| RIGI | RNA sensor RIG-I | -0.0434651 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0431147 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0421944 |
| FBXO32 | F-box protein 32 | -0.0355043 |
| MX2 | MX dynamin-like GTPase 2 | -0.0354094 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0348999 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0343429 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0337122 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0331682 |
| MX1 | MX dynamin-like GTPase 1 | -0.0326079 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0325944 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0322967 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0284825 |
| INTS6 | integrator complex subunit 6 | -0.0280228 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.027937 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0277893 |
| PGBD5 | piggyBac transposable element derived 5 | -0.0252169 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0252144 |
| RAD51B | RAD51 paralog B | -0.025197 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0246871 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.024291 |
| ARHGAP20 | Rho GTPase activating protein 20 | -0.0242446 |
| EFNA5 | ephrin-A5 | -0.0237487 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.022489 |
| GOLGB1 | golgin B1 | -0.022255 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0221557 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0219346 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0218237 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0212551 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0210891 |
| AEBP2 | AE binding protein 2 | -0.0207129 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0201475 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0199905 |
| CDK13 | cyclin-dependent kinase 13 | -0.0198291 |
| FHIT | fragile histidine triad | -0.0196798 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0196552 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0195071 |
| CALR | calreticulin | -0.0191737 |
| EXOC4 | exocyst complex component 4 | -0.0189414 |
| RAI14 | retinoic acid induced 14 | -0.018782 |
| ATXN1 | ataxin 1 | -0.0187325 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0186079 |
| PLSCR1 | phospholipid scramblase 1 | -0.0183407 |
| RPLP1 | ribosomal protein, large, P1 | -0.0182881 |
| SP100 | SP100 nuclear antigen | -0.0181348 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0180363 |
| RBM47 | RNA binding motif protein 47 | -0.017808 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0176874 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0173715 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0169401 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0169363 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0169308 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0165986 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0164597 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.0163383 |
| RRBP1 | ribosome binding protein 1 | -0.0161086 |
| TBCA | tubulin folding cofactor A | -0.0157754 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0156885 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | -0.0155363 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0154257 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0154098 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0153312 |
| RPS29 | ribosomal protein S29 | -0.0153219 |
| SETX | senataxin | -0.0152013 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0150308 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0148749 |
| BPTF | bromodomain PHD finger transcription factor | -0.0148634 |
| ETV6 | ets variant 6 | -0.0148446 |
| STEAP4 | STEAP family member 4 | -0.0147785 |
| S100A10 | S100 calcium binding protein A10 | -0.014681 |
| CPM | carboxypeptidase M | -0.0146705 |
| IFI44L | interferon-induced protein 44-like | -0.0146178 |
| PPM1K | protein phosphatase, Mg2+/Mn2+ dependent, 1K | -0.0143374 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0141594 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.0139277 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0139099 |
| HDAC9 | histone deacetylase 9 | -0.0139034 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0138492 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0137837 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0137032 |
| RPS24 | ribosomal protein S24 | -0.0135182 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0134323 |
| JUN | jun proto-oncogene | -0.0134189 |
| ZNF638 | zinc finger protein 638 | -0.0134063 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.013329 |
| USP34 | ubiquitin specific peptidase 34 | -0.01332 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0133163 |
| LAP3 | leucine aminopeptidase 3 | -0.01309 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0130262 |
