| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.325888 |
| FN1 | fibronectin 1 | 0.171485 |
| COL5A2 | collagen, type V, alpha 2 | 0.120397 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.114694 |
| PDE10A | phosphodiesterase 10A | 0.114073 |
| MCL1 | myeloid cell leukemia 1 | 0.110421 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0975232 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0950737 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0860329 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0824693 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0700016 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0691866 |
| CDH13 | cadherin 13 | 0.0679348 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0640755 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0632504 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0630669 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.061738 |
| DST | dystonin | 0.0606977 |
| ASPH | aspartate beta-hydroxylase | 0.0593868 |
| PCBP3 | poly(rC) binding protein 3 | 0.0574167 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0534248 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0522856 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0508853 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0493096 |
| EFNA5 | ephrin-A5 | 0.0492861 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0479703 |
| AUTS2 | autism susceptibility candidate 2 | 0.0476859 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0475254 |
| DOCK5 | dedicator of cytokinesis 5 | 0.047385 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0450798 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0440077 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0439336 |
| GDA | guanine deaminase | 0.0425515 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0420665 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0416739 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0403463 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0402782 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0399398 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.038833 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0387465 |
| COL4A6 | collagen, type IV, alpha 6 | 0.0375542 |
| TBXT | T-box transcription factor T | 0.0374448 |
| GRAMD1B | GRAM domain containing 1B | 0.035816 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0356546 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0353685 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0349832 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0348986 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.0343568 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0342484 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0340041 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.033697 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0336172 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0333715 |
| HLA-A | major histocompatibility complex, class I, A | 0.0332214 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0332057 |
| NRCAM | neuronal cell adhesion molecule | 0.0329116 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0328237 |
| SMYD3 | SET and MYND domain containing 3 | 0.0328227 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0326491 |
| KYNU | kynureninase | 0.0323155 |
| RAD51B | RAD51 paralog B | 0.031872 |
| PRELID2 | PRELI domain containing 2 | 0.0315988 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0305126 |
| VCL | vinculin | 0.0302681 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0300456 |
| MSN | moesin | 0.0299396 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0298901 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0294226 |
| RPL3 | ribosomal protein L3 | 0.0291618 |
| LSAMP | limbic system-associated membrane protein | 0.0289981 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0289331 |
| LAMA5 | laminin, alpha 5 | 0.0286503 |
| ENO1 | enolase 1, (alpha) | 0.0286163 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0282826 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | 0.0280018 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0278682 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.02781 |
| STC1 | stanniocalcin 1 | 0.0271302 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0265185 |
| GPC6 | glypican 6 | 0.0262495 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0256952 |
| ATXN1 | ataxin 1 | 0.0254379 |
| TENM3 | teneurin transmembrane protein 3 | 0.0253819 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0252156 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0245984 |
| MAP7 | microtubule-associated protein 7 | 0.0243565 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0242813 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0242513 |
| KIAA0825 | KIAA0825 | 0.0235958 |
| FLNA | filamin A, alpha | 0.0234787 |
| HLA-B | major histocompatibility complex, class I, B | 0.0233365 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.023333 |
| RPS12 | ribosomal protein S12 | 0.0233231 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.0232665 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0230221 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0229783 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0229431 |
| RPL37A | ribosomal protein L37a | 0.0228158 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0224747 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.022419 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.162576 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0800767 |
| TXNRD1 | thioredoxin reductase 1 | -0.058332 |
| TMSB10 | thymosin beta 10 | -0.056508 |
| FTL | ferritin, light polypeptide | -0.0527114 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.049936 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0479642 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0403144 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0398059 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0391253 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0377755 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0351841 |
| RPS24 | ribosomal protein S24 | -0.0311246 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0310747 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0291821 |
| CANX | calnexin | -0.0280924 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0262368 |
| TKT | transketolase | -0.0238515 |
| SPAG9 | sperm associated antigen 9 | -0.0237314 |
| PTMA | prothymosin, alpha | -0.02295 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0226624 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0224859 |
| GOLGA4 | golgin A4 | -0.0224334 |
| RPL12 | ribosomal protein L12 | -0.0222781 |
| RTN4 | reticulon 4 | -0.0219237 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0215904 |
| RGS2 | regulator of G-protein signaling 2 | -0.0210328 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.02085 |
| MATR3 | matrin 3 | -0.0207557 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0207362 |
| RPLP1 | ribosomal protein, large, P1 | -0.0206943 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0203709 |
| S100A10 | S100 calcium binding protein A10 | -0.0199414 |
| WDR43 | WD repeat domain 43 | -0.0197296 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0194513 |
| RPLP0 | ribosomal protein, large, P0 | -0.0192584 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.019151 |
| RPL23 | ribosomal protein L23 | -0.0191235 |
| MORF4L2 | mortality factor 4 like 2 | -0.0182827 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0180064 |
| NOP58 | NOP58 ribonucleoprotein | -0.0179546 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0175393 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.017417 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0173837 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0173734 |
| YBX1 | Y box binding protein 1 | -0.0166874 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0165704 |
| S100A6 | S100 calcium binding protein A6 | -0.0165566 |
| USP3 | ubiquitin specific peptidase 3 | -0.0161122 |
| RBM39 | RNA binding motif protein 39 | -0.0157262 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0156008 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0154653 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0153992 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0152866 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0152802 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0151006 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0149742 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0147697 |
| SRGN | serglycin | -0.0146852 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.0145288 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0143634 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0141788 |
| KIF21A | kinesin family member 21A | -0.0139057 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0136459 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0135671 |
| ZNF207 | zinc finger protein 207 | -0.0135335 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0133003 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0131004 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0130519 |
| RBM25 | RNA binding motif protein 25 | -0.0130171 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0130019 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0129551 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0127055 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0126412 |
| RIOK3 | RIO kinase 3 | -0.01252 |
| NPR2 | natriuretic peptide receptor 2 | -0.0125198 |
| TNPO1 | transportin 1 | -0.0124574 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0124529 |
| OGA | O-GlcNAcase | -0.0124058 |
| RPL32 | ribosomal protein L32 | -0.0120922 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0120902 |
| PHIP | pleckstrin homology domain interacting protein | -0.0120317 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0119999 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | -0.011998 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0119276 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0118913 |
| PLCB4 | phospholipase C, beta 4 | -0.0116573 |
| ARF1 | ADP-ribosylation factor 1 | -0.011645 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0116406 |
| RNF145 | ring finger protein 145 | -0.0113251 |
| RPL6 | ribosomal protein L6 | -0.0113213 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0112223 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0110468 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0110355 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0108961 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.010893 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0108897 |
| ANXA1 | annexin A1 | -0.0106369 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0105916 |
| ENAH | enabled homolog (Drosophila) | -0.0105151 |
