| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | 0.145853 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.132491 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.124586 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.122061 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.108449 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0744451 |
| POTEF | POTE ankyrin domain family, member F | 0.0742175 |
| GPC3 | glypican 3 | 0.0727056 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0692786 |
| ACTG1 | actin gamma 1 | 0.0678705 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0659713 |
| H1-0 | H1.0 linker histone | 0.0623835 |
| TENM3 | teneurin transmembrane protein 3 | 0.0591797 |
| CENPF | centromere protein F, 350/400kDa | 0.0567512 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0567017 |
| ITGAV | integrin, alpha V | 0.0540055 |
| PDGFC | platelet derived growth factor C | 0.0536327 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0484793 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0477312 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0472165 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0463001 |
| CCN2 | cellular communication network factor 2 | 0.0462964 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.043822 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0436939 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0434937 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0430554 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0429827 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0418157 |
| GNAS | GNAS complex locus | 0.041372 |
| MPG | N-methylpurine-DNA glycosylase | 0.0395075 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.0391905 |
| TMSB4X | thymosin beta 4, X-linked | 0.0375622 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0375199 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0374768 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0373796 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0370636 |
| ANXA1 | annexin A1 | 0.0365727 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0361332 |
| CS | citrate synthase | 0.0356987 |
| MEIS2 | Meis homeobox 2 | 0.035496 |
| METAP2 | methionyl aminopeptidase 2 | 0.0353131 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0351715 |
| ZNF608 | zinc finger protein 608 | 0.0349774 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0342872 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0340133 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0338083 |
| LYST | lysosomal trafficking regulator | 0.0336018 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0327826 |
| PCM1 | pericentriolar material 1 | 0.0325433 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0325145 |
| CBX3 | chromobox homolog 3 | 0.0324173 |
| ARHGAP15 | Rho GTPase activating protein 15 | 0.0322229 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.0321526 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0320966 |
| FAM171B | family with sequence similarity 171, member B | 0.0320654 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0317646 |
| GLO1 | glyoxalase I | 0.0317006 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0316265 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0314463 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0309579 |
| RFPL4B | ret finger protein-like 4B | 0.0308206 |
| TMEM64 | transmembrane protein 64 | 0.0307905 |
| FOXP2 | forkhead box P2 | 0.0305483 |
| WDR43 | WD repeat domain 43 | 0.0304841 |
| RPS2 | ribosomal protein S2 | 0.0304779 |
| TUBB | tubulin, beta class I | 0.0301039 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0298919 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0294177 |
| FIGN | fidgetin | 0.0286727 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 0.0285544 |
| TNPO1 | transportin 1 | 0.0284983 |
| ANXA5 | annexin A5 | 0.0283948 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0281011 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0274923 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0270015 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0268626 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0267456 |
| MORF4L2 | mortality factor 4 like 2 | 0.0265595 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0264718 |
| COL1A2 | collagen, type I, alpha 2 | 0.0264071 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0262946 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0262367 |
| H1-5 | H1.5 linker histone, cluster member | 0.026191 |
| SP3 | Sp3 transcription factor | 0.0260425 |
| RBM25 | RNA binding motif protein 25 | 0.026026 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0259348 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.025775 |
| PROS1 | protein S (alpha) | 0.0254593 |
| CCNA2 | cyclin A2 | 0.0251695 |
| TMEM123 | transmembrane protein 123 | 0.0250906 |
| RAI1 | retinoic acid induced 1 | 0.0250538 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0247515 |
| DLX2 | distal-less homeobox 2 | 0.024623 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.024622 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0243792 |
| DSTN | destrin (actin depolymerizing factor) | 0.0242465 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0241189 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0239425 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0238736 |
| SNX6 | sorting nexin 6 | 0.0238675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.103871 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.065098 |
| AHNAK | AHNAK nucleoprotein | -0.0634334 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0613337 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0573019 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0512202 |
| HDAC9 | histone deacetylase 9 | -0.0505353 |
| NTM | neurotrimin | -0.0493341 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0471024 |
| FNDC3B | fibronectin type III domain containing 3B | -0.047015 |
| UBC | ubiquitin C | -0.0453895 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0452486 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0441858 |
| ATXN2 | ataxin 2 | -0.0437254 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0436005 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0399451 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0397515 |
| MED13L | mediator complex subunit 13-like | -0.0396836 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.039305 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0389716 |
| RPS27A | ribosomal protein S27a | -0.0388705 |
| RPL23 | ribosomal protein L23 | -0.0380056 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0377583 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0375935 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0369851 |
| YAP1 | Yes-associated protein 1 | -0.0363416 |
| RPLP2 | ribosomal protein, large, P2 | -0.0355215 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.034762 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0333061 |
| PGK1 | phosphoglycerate kinase 1 | -0.0329718 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0328922 |
| NUP58 | nucleoporin 58 | -0.0327497 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0326521 |
| HMCN1 | hemicentin 1 | -0.0321748 |
| NDRG1 | N-myc downstream regulated 1 | -0.032029 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0320196 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0317214 |
| RPLP1 | ribosomal protein, large, P1 | -0.0316941 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0310737 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0308195 |
| OGA | O-GlcNAcase | -0.0304041 |
| FN1 | fibronectin 1 | -0.0302876 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0297715 |
| RFX7 | regulatory factor X, 7 | -0.0294601 |
| SMYD3 | SET and MYND domain containing 3 | -0.0293678 |
| RAD51B | RAD51 paralog B | -0.0290145 |
| MYO6 | myosin VI | -0.0289654 |
| PHIP | pleckstrin homology domain interacting protein | -0.028961 |
| OPHN1 | oligophrenin 1 | -0.0284565 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0282934 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0281799 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.028175 |
| PTMA | prothymosin, alpha | -0.0276673 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0275194 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0272006 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0271725 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0271663 |
| PRELID2 | PRELI domain containing 2 | -0.0269904 |
| CCNY | cyclin Y | -0.0268858 |
| RPL35A | ribosomal protein L35a | -0.0268208 |
| FMNL2 | formin-like 2 | -0.0267535 |
| RYBP | RING1 and YY1 binding protein | -0.0265735 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0263705 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0253995 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0253363 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0253339 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0252355 |
| MRTFA | myocardin related transcription factor A | -0.0250954 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0249235 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0247646 |
| RPS8 | ribosomal protein S8 | -0.0245811 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0245803 |
| QKI | QKI, KH domain containing, RNA binding | -0.0244417 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0243645 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0243167 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0242871 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0242498 |
| ERBIN | erbb2 interacting protein | -0.0242416 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0242231 |
| MYO10 | myosin X | -0.0237342 |
| CTBP2 | C-terminal binding protein 2 | -0.0234735 |
| TBL1X | transducin (beta)-like 1X-linked | -0.02345 |
| UBN2 | ubinuclein 2 | -0.0233265 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0231358 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0230433 |
| FTL | ferritin, light polypeptide | -0.0229941 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0229758 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0229596 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0228469 |
| FLNB | filamin B, beta | -0.0226712 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0225684 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0225567 |
| SQSTM1 | sequestosome 1 | -0.0224477 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0223895 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0223455 |
| AGTPBP1 | ATP/GTP binding protein 1 | -0.0223175 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0222509 |
| NEBL | nebulette | -0.0222483 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0221763 |
| RPL31 | ribosomal protein L31 | -0.022127 |
