| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in RKO cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_RKO drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0875555 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0873489 |
| FRMD6 | FERM domain containing 6 | 0.0871231 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0851447 |
| NAV3 | neuron navigator 3 | 0.0793532 |
| MCL1 | myeloid cell leukemia 1 | 0.0754812 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0748042 |
| NAV2 | neuron navigator 2 | 0.0716347 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0689625 |
| ACTG1 | actin gamma 1 | 0.0688287 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0643218 |
| HDAC9 | histone deacetylase 9 | 0.0641412 |
| DGKI | diacylglycerol kinase, iota | 0.0602164 |
| JMJD1C | jumonji domain containing 1C | 0.0585745 |
| FRMD4A | FERM domain containing 4A | 0.0584805 |
| RPL3 | ribosomal protein L3 | 0.0581238 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.057001 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0569695 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0546223 |
| POTEF | POTE ankyrin domain family, member F | 0.0536985 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.052776 |
| FLNA | filamin A, alpha | 0.0522777 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.050017 |
| NABP1 | nucleic acid binding protein 1 | 0.0482679 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0473385 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.046997 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0467815 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0460963 |
| FLNB | filamin B, beta | 0.0456237 |
| HMGA2 | high mobility group AT-hook 2 | 0.0445079 |
| RPL37A | ribosomal protein L37a | 0.0426053 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0424415 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0418043 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0408491 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0406517 |
| ZNF438 | zinc finger protein 438 | 0.0397647 |
| EXOC4 | exocyst complex component 4 | 0.0394595 |
| LOC112694756 | uncharaterized LOC112694756 | 0.037806 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0374307 |
| RPS2 | ribosomal protein S2 | 0.0362168 |
| ENO1 | enolase 1, (alpha) | 0.0357273 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0349777 |
| SQSTM1 | sequestosome 1 | 0.0346487 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.034575 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0340419 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0338553 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0333023 |
| PGK1 | phosphoglycerate kinase 1 | 0.0332541 |
| GPATCH2L | G patch domain containing 2-like | 0.0328168 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0326181 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0323331 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0322745 |
| EGR1 | early growth response 1 | 0.031899 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0316381 |
| FAM91A1 | family with sequence similarity 91, member A1 | 0.0314204 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0314057 |
| BNC2 | basonuclin 2 | 0.0310348 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0308255 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0307382 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0305355 |
| RPL11 | ribosomal protein L11 | 0.0300492 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0288221 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0286611 |
| TTR | transthyretin | 0.0285668 |
| RPS12 | ribosomal protein S12 | 0.0285103 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0283832 |
| FNIP1 | folliculin interacting protein 1 | 0.0275522 |
| PTK2 | protein tyrosine kinase 2 | 0.027513 |
| ASPH | aspartate beta-hydroxylase | 0.0273565 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0273189 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.027197 |
| ACTN1 | actinin, alpha 1 | 0.0271597 |
| CAPRIN2 | caprin family member 2 | 0.0271327 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0270602 |
| SMTN | smoothelin | 0.0269683 |
| RPL27 | ribosomal protein L27 | 0.0268366 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0262603 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0257443 |
| PRKCE | protein kinase C, epsilon | 0.0254398 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0254004 |
| GLRX | glutaredoxin (thioltransferase) | 0.0252365 |
| RAD51B | RAD51 paralog B | 0.0252112 |
| RPSA | ribosomal protein SA | 0.025107 |
| CALD1 | caldesmon 1 | 0.0250442 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0247191 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0246917 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0242839 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | 0.0241724 |
| KIF1B | kinesin family member 1B | 0.0239082 |
| PCNX4 | pecanex 4 | 0.0238984 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0237955 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0235972 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0235721 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0235153 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0233292 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0232585 |
| HLA-A | major histocompatibility complex, class I, A | 0.023184 |
| PCBP2 | poly(rC) binding protein 2 | 0.0231608 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0228935 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.022479 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.170574 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.143125 |
| PTMA | prothymosin, alpha | -0.0674812 |
| RPLP1 | ribosomal protein, large, P1 | -0.0592099 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0526895 |
| RPLP0 | ribosomal protein, large, P0 | -0.0492765 |
| TMSB10 | thymosin beta 10 | -0.0474325 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0450713 |
| RPS24 | ribosomal protein S24 | -0.0438397 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0429458 |
| RPL23 | ribosomal protein L23 | -0.0412884 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0412201 |
| RPS21 | ribosomal protein S21 | -0.0396434 |
| MTDH | metadherin | -0.0390409 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0352293 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.034801 |
| RPL36 | ribosomal protein L36 | -0.0343793 |
| AHNAK | AHNAK nucleoprotein | -0.033003 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0327294 |
| RPL7 | ribosomal protein L7 | -0.0321856 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0314598 |
| RPL34 | ribosomal protein L34 | -0.0311125 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0308991 |
| TPX2 | TPX2, microtubule-associated | -0.0295702 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0293788 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0292421 |
| GNAS | GNAS complex locus | -0.0290486 |
| MT1X | metallothionein 1X | -0.0290084 |
| USP3 | ubiquitin specific peptidase 3 | -0.0288803 |
| MATR3 | matrin 3 | -0.0281186 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0276328 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0274712 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0273564 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0270955 |
| S100A9 | S100 calcium binding protein A9 | -0.0269644 |
| HMGB2 | high mobility group box 2 | -0.0264917 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0263554 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0262391 |
| RPL32 | ribosomal protein L32 | -0.0258969 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0258775 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0256091 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.025565 |
| DEK | DEK proto-oncogene | -0.0247721 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.024478 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0241513 |
| RPLP2 | ribosomal protein, large, P2 | -0.0238201 |
| RPL12 | ribosomal protein L12 | -0.0235533 |
| RBL1 | retinoblastoma-like 1 | -0.0229569 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.022651 |
| RRBP1 | ribosome binding protein 1 | -0.022531 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0225201 |
| NOP58 | NOP58 ribonucleoprotein | -0.022331 |
| RPL8 | ribosomal protein L8 | -0.0220644 |
| TPM4 | tropomyosin 4 | -0.0217806 |
| FAM162A | family with sequence similarity 162, member A | -0.0216243 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0215949 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.0213931 |
| RPS5 | ribosomal protein S5 | -0.0212471 |
| HMGB1 | high mobility group box 1 | -0.0211351 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0209135 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0207871 |
| RPL14 | ribosomal protein L14 | -0.0203204 |
| RPS19 | ribosomal protein S19 | -0.020318 |
| CBX3 | chromobox homolog 3 | -0.0202618 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0201902 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0201269 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0199371 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0197436 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0195051 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0194131 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0193367 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0192564 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0191596 |
| RPL18 | ribosomal protein L18 | -0.0191123 |
| RPL26 | ribosomal protein L26 | -0.0188618 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0188318 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.018747 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0185871 |
| CANX | calnexin | -0.0185367 |
| PABPN1 | poly(A) binding protein, nuclear 1 | -0.0184256 |
| RPL35A | ribosomal protein L35a | -0.0184184 |
| RPS6 | ribosomal protein S6 | -0.0183296 |
| S100A10 | S100 calcium binding protein A10 | -0.0182871 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0182502 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0179737 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0179342 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0178987 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0178555 |
| BST2 | bone marrow stromal cell antigen 2 | -0.0177338 |
| MAP4 | microtubule-associated protein 4 | -0.0177303 |
| NEMF | nuclear export mediator factor | -0.017707 |
| SEPTIN7 | septin 7 | -0.0176659 |
| TKT | transketolase | -0.0176039 |
| YBX1 | Y box binding protein 1 | -0.0171887 |
| NPR2 | natriuretic peptide receptor 2 | -0.0171813 |
| UPP1 | uridine phosphorylase 1 | -0.0171372 |
| FTL | ferritin, light polypeptide | -0.0169493 |
| WDR45B | WD repeat domain 45B | -0.0169489 |
| GOLM2 | golgi membrane protein 2 | -0.0169405 |
| TASP1 | taspase, threonine aspartase, 1 | -0.0168376 |
