| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dimethyl fumarate_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.453042 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.117335 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0889346 |
| CD44 | CD44 molecule (Indian blood group) | 0.0801258 |
| MSN | moesin | 0.0761268 |
| CENPF | centromere protein F, 350/400kDa | 0.0750472 |
| NAV2 | neuron navigator 2 | 0.0680644 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0678526 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0669369 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0656644 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0656374 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0627173 |
| TGM2 | transglutaminase 2 | 0.0610272 |
| NRP1 | neuropilin 1 | 0.0600739 |
| PGK1 | phosphoglycerate kinase 1 | 0.0597009 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0576705 |
| VIM | vimentin | 0.0567836 |
| ZNF292 | zinc finger protein 292 | 0.0554218 |
| AFAP1 | actin filament associated protein 1 | 0.0547142 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.054466 |
| MKI67 | marker of proliferation Ki-67 | 0.0537257 |
| POTEF | POTE ankyrin domain family, member F | 0.053225 |
| FRMD4A | FERM domain containing 4A | 0.0523674 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0516712 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0515741 |
| FLNB | filamin B, beta | 0.0509427 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0494633 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0478682 |
| RUNX1 | runt-related transcription factor 1 | 0.0476149 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0473494 |
| TPX2 | TPX2, microtubule-associated | 0.0461716 |
| RTN4 | reticulon 4 | 0.04549 |
| YEATS2 | YEATS domain containing 2 | 0.0447839 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0442425 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0435559 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0417555 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.040606 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0394367 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0390271 |
| SETD5 | SET domain containing 5 | 0.038857 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0388166 |
| ANLN | anillin, actin binding protein | 0.038122 |
| MEF2A | myocyte enhancer factor 2A | 0.0379821 |
| RAD51B | RAD51 paralog B | 0.0378267 |
| ZNF148 | zinc finger protein 148 | 0.0376999 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0376702 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0374299 |
| CDK19 | cyclin-dependent kinase 19 | 0.0370988 |
| RBM39 | RNA binding motif protein 39 | 0.0369072 |
| DIAPH3 | diaphanous-related formin 3 | 0.0366371 |
| ATXN1 | ataxin 1 | 0.0364414 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0361191 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0360672 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0353675 |
| SBF2 | SET binding factor 2 | 0.0351037 |
| ENO1 | enolase 1, (alpha) | 0.0348752 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0347871 |
| CENPE | centromere protein E, 312kDa | 0.0347669 |
| NF1 | neurofibromin 1 | 0.034745 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0346705 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0345597 |
| GOLGA4 | golgin A4 | 0.0343148 |
| AFDN | afadin, adherens junction formation factor | 0.0342247 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0340599 |
| JMJD1C | jumonji domain containing 1C | 0.0338866 |
| ACTN4 | actinin, alpha 4 | 0.0337387 |
| ANO6 | anoctamin 6 | 0.0335849 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.033523 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0331221 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.03305 |
| H1-0 | H1.0 linker histone | 0.0330373 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0329831 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0329694 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0328359 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0324745 |
| LDHA | lactate dehydrogenase A | 0.0323747 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0319325 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0319085 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0317764 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0310617 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.03103 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0306274 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0305861 |
| TMEM178B | transmembrane protein 178B | 0.030278 |
| ANXA2 | annexin A2 | 0.0302332 |
| COL5A1 | collagen, type V, alpha 1 | 0.0301891 |
| HDLBP | high density lipoprotein binding protein | 0.0295803 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0295347 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0294276 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0292202 |
| NDRG1 | N-myc downstream regulated 1 | 0.0291899 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0291311 |
| APP | amyloid beta (A4) precursor protein | 0.0290447 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0288944 |
| KIF4A | kinesin family member 4A | 0.0286839 |
| MYO1B | myosin IB | 0.0286572 |
| NBAS | neuroblastoma amplified sequence | 0.0286367 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0284266 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.028306 |
| ACTN1 | actinin, alpha 1 | 0.0282939 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HLA-B | major histocompatibility complex, class I, B | -0.120004 |
| B2M | beta-2-microglobulin | -0.107183 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.104769 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0870452 |
| FTL | ferritin, light polypeptide | -0.0868111 |
| CDH13 | cadherin 13 | -0.0696572 |
| TMSB10 | thymosin beta 10 | -0.0669389 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.059021 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0588635 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.055598 |
| MT2A | metallothionein 2A | -0.0530133 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.052822 |
| IER3 | immediate early response 3 | -0.0470711 |
| HLA-A | major histocompatibility complex, class I, A | -0.0461331 |
| PTMA | prothymosin, alpha | -0.0456632 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0448009 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0433571 |
| STC1 | stanniocalcin 1 | -0.0394243 |
| INHBA | inhibin, beta A | -0.0379963 |
| HLA-C | major histocompatibility complex, class I, C | -0.0376801 |
| RPL35A | ribosomal protein L35a | -0.0374615 |
| IL1B | interleukin 1, beta | -0.0371027 |
| RPLP1 | ribosomal protein, large, P1 | -0.0370919 |
| SP100 | SP100 nuclear antigen | -0.0368243 |
| HLA-E | major histocompatibility complex, class I, E | -0.035625 |
| COL1A1 | collagen, type I, alpha 1 | -0.0345926 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0345226 |
| CADM1 | cell adhesion molecule 1 | -0.0345003 |
| RPL34 | ribosomal protein L34 | -0.0323606 |
| CALR | calreticulin | -0.032351 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0306811 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.027744 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0260547 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0257608 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0253706 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0252064 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0246948 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0246698 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0246442 |
| RPL31 | ribosomal protein L31 | -0.0246222 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0241064 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0238541 |
| RPS19 | ribosomal protein S19 | -0.0238185 |
| S100A9 | S100 calcium binding protein A9 | -0.0237952 |
| RPS27A | ribosomal protein S27a | -0.0237464 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0235072 |
| RPS24 | ribosomal protein S24 | -0.0229002 |
| RIGI | RNA sensor RIG-I | -0.022374 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0220547 |
| RND3 | Rho family GTPase 3 | -0.0218753 |
| RPL12 | ribosomal protein L12 | -0.0216011 |
| HDAC9 | histone deacetylase 9 | -0.0215125 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0214161 |
| ITGA1 | integrin, alpha 1 | -0.0214143 |
| GNAS | GNAS complex locus | -0.0211241 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0209767 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0209133 |
| CD63 | CD63 molecule | -0.0206086 |
| AGBL1 | ATP/GTP binding protein-like 1 | -0.0203735 |
| RYBP | RING1 and YY1 binding protein | -0.0202785 |
| KYNU | kynureninase | -0.0201982 |
| ADM | adrenomedullin | -0.0199758 |
| CCDC138 | coiled-coil domain containing 138 | -0.0199482 |
| OXR1 | oxidation resistance 1 | -0.0199306 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0196993 |
| XAF1 | XIAP associated factor 1 | -0.019691 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0196424 |
| RPS25 | ribosomal protein S25 | -0.0195541 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0194629 |
| RPS17 | ribosomal protein S17 | -0.0193206 |
| SYNDIG1 | synapse differentiation inducing 1 | -0.0191124 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0188681 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0182419 |
| RPS21 | ribosomal protein S21 | -0.018094 |
| COL5A3 | collagen, type V, alpha 3 | -0.0179718 |
| RPS6 | ribosomal protein S6 | -0.0179376 |
| SEC61G | Sec61 gamma subunit | -0.0178776 |
| RPL36 | ribosomal protein L36 | -0.0177166 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0176127 |
| CST3 | cystatin C | -0.0176119 |
| S100A11 | S100 calcium binding protein A11 | -0.0175917 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0175623 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.01742 |
| RPS8 | ribosomal protein S8 | -0.0174165 |
| RPL23 | ribosomal protein L23 | -0.0173681 |
| RPL30 | ribosomal protein L30 | -0.0170681 |
| RPLP2 | ribosomal protein, large, P2 | -0.0168808 |
| RPL37A | ribosomal protein L37a | -0.0167112 |
| RPL32 | ribosomal protein L32 | -0.0165083 |
| FAM162A | family with sequence similarity 162, member A | -0.0164181 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0164053 |
| S100A10 | S100 calcium binding protein A10 | -0.0158278 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0158124 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0158005 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0157456 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0155845 |
| RAI14 | retinoic acid induced 14 | -0.0155619 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0154867 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0153351 |
| CCND1 | cyclin D1 | -0.0153124 |
