| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in SHP-77 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_SHP-77 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE10A | phosphodiesterase 10A | 0.306207 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0802358 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0793065 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.079194 |
| ENO1 | enolase 1, (alpha) | 0.0724409 |
| PEG10 | paternally expressed 10 | 0.0715817 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0700353 |
| VGF | VGF nerve growth factor inducible | 0.0650821 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.056225 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0546386 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0546046 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.052787 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.050942 |
| CENPF | centromere protein F, 350/400kDa | 0.0501978 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0482866 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0460161 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0450175 |
| CALCA | calcitonin-related polypeptide alpha | 0.0446614 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0443196 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0427172 |
| POTEF | POTE ankyrin domain family, member F | 0.0409095 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.039428 |
| ZNF292 | zinc finger protein 292 | 0.0383728 |
| GRAMD4 | GRAM domain containing 4 | 0.0379002 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0378416 |
| CADM1 | cell adhesion molecule 1 | 0.0375127 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0370694 |
| IRS2 | insulin receptor substrate 2 | 0.0363319 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0363014 |
| FOXN3 | forkhead box N3 | 0.0357651 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0351138 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.0345948 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0344477 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0340979 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0339603 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0335138 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0333648 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.0330376 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0325573 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.031763 |
| TPM3 | tropomyosin 3 | 0.0309058 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0306792 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0296479 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0295439 |
| PCM1 | pericentriolar material 1 | 0.0294683 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.0294223 |
| CPE | carboxypeptidase E | 0.0292625 |
| GPHN | gephyrin | 0.0291692 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0289453 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.028526 |
| SET | SET nuclear proto-oncogene | 0.0282583 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0280838 |
| UBE2QL1 | ubiquitin-conjugating enzyme E2Q family-like 1 | 0.0276297 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0276134 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.027477 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0273619 |
| CCDC88A | coiled-coil domain containing 88A | 0.0272297 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0270141 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0268753 |
| INTS1 | integrator complex subunit 1 | 0.0268382 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0266877 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0266643 |
| FKBP9 | FK506 binding protein 9, 63 kDa | 0.0262696 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0262343 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0261977 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0257303 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0256664 |
| NCKAP5 | NCK-associated protein 5 | 0.0255293 |
| GSE1 | Gse1 coiled-coil protein | 0.0254615 |
| FAT1 | FAT atypical cadherin 1 | 0.0253394 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0253116 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0252156 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0251386 |
| RPS12 | ribosomal protein S12 | 0.0250351 |
| PNN | pinin, desmosome associated protein | 0.0248002 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0245412 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0245183 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0244831 |
| AUTS2 | autism susceptibility candidate 2 | 0.0242072 |
| MTMR7 | myotubularin related protein 7 | 0.0238705 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0237431 |
| TRIM9 | tripartite motif containing 9 | 0.0233065 |
| SIK3 | SIK family kinase 3 | 0.0231601 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.023142 |
| RAD51B | RAD51 paralog B | 0.0230539 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0229109 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0228257 |
| HMGB3 | high mobility group box 3 | 0.0226611 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0226463 |
| NBAS | neuroblastoma amplified sequence | 0.0223831 |
| VEGFA | vascular endothelial growth factor A | 0.0222835 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0221418 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.022122 |
| PARD3 | par-3 family cell polarity regulator | 0.022092 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0217528 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0212097 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0211316 |
| TOX | thymocyte selection-associated high mobility group box | 0.0211159 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0210864 |
| YY1AP1 | YY1 associated protein 1 | 0.0207506 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.116399 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.113457 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0782907 |
| FTL | ferritin, light polypeptide | -0.0413242 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0359943 |
| SNTG1 | syntrophin, gamma 1 | -0.0349921 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0296762 |
| GPC5 | glypican 5 | -0.0293984 |
| RPL35A | ribosomal protein L35a | -0.0286564 |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | -0.0285334 |
| TENM1 | teneurin transmembrane protein 1 | -0.0283946 |
| CANX | calnexin | -0.0273163 |
| CHGA | chromogranin A | -0.0268832 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0260396 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0258802 |
| GNAS | GNAS complex locus | -0.0250617 |
| PTCHD4 | patched domain containing 4 | -0.024611 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0242673 |
| CA8 | carbonic anhydrase VIII | -0.0234333 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0229436 |
| SCG2 | secretogranin II | -0.0228539 |
| RPL38 | ribosomal protein L38 | -0.0224507 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0222367 |
| ZNF804A | zinc finger protein 804A | -0.0218741 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0214116 |
| TXNRD1 | thioredoxin reductase 1 | -0.0211467 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0210651 |
| RPS27A | ribosomal protein S27a | -0.0206585 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0206103 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0205917 |
| PARK7 | parkinson protein 7 | -0.0204075 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0202014 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0198376 |
| UBB | ubiquitin B | -0.0192658 |
| RPLP1 | ribosomal protein, large, P1 | -0.0192607 |
| RPS16 | ribosomal protein S16 | -0.0189692 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0187577 |
| RPS24 | ribosomal protein S24 | -0.018733 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.018463 |
| RPL31 | ribosomal protein L31 | -0.0183081 |
| NRG1 | neuregulin 1 | -0.0182674 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0181684 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0179949 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0178691 |
| RPL4 | ribosomal protein L4 | -0.0178255 |
| RPL12 | ribosomal protein L12 | -0.0176417 |
| RPL34 | ribosomal protein L34 | -0.0174098 |
| TKT | transketolase | -0.0172425 |
| GPC6 | glypican 6 | -0.0172077 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0168593 |
| IER3 | immediate early response 3 | -0.0167534 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0165352 |
| SRP72 | signal recognition particle 72kDa | -0.0160967 |
| SCAMP1 | secretory carrier membrane protein 1 | -0.0160638 |
| JUN | jun proto-oncogene | -0.0158563 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0158531 |
| NDRG1 | N-myc downstream regulated 1 | -0.0156945 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0156777 |
| AGMO | alkylglycerol monooxygenase | -0.0152303 |
| RPL6 | ribosomal protein L6 | -0.0151867 |
| ARF1 | ADP-ribosylation factor 1 | -0.0151783 |
| SLC35F4 | solute carrier family 35, member F4 | -0.0151663 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0151201 |
| TMSB4X | thymosin beta 4, X-linked | -0.0151137 |
| PCDH9 | protocadherin 9 | -0.0151082 |
| MORF4L2 | mortality factor 4 like 2 | -0.0150951 |
| RPS23 | ribosomal protein S23 | -0.0149024 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0148656 |
| DYM | dymeclin | -0.0148062 |
| LSAMP | limbic system-associated membrane protein | -0.0144806 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0144605 |
| CGGBP1 | CGG triplet repeat binding protein 1 | -0.0143774 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0143769 |
| FOXC1 | forkhead box C1 | -0.0143391 |
| TUBA1B | tubulin, alpha 1b | -0.0142145 |
| RPL32 | ribosomal protein L32 | -0.0142145 |
| VIM | vimentin | -0.0141786 |
| NPR2 | natriuretic peptide receptor 2 | -0.0139654 |
| EIF2S1 | eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa | -0.0138974 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0136122 |
| TMEM123 | transmembrane protein 123 | -0.0135793 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0134987 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0134844 |
| UCMA | upper zone of growth plate and cartilage matrix associated | -0.0134599 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0133544 |
| GDAP1 | ganglioside induced differentiation associated protein 1 | -0.0132463 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0131754 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0130717 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0130521 |
| RPL36AL | ribosomal protein L36a-like | -0.0129759 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | -0.0128649 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | -0.0127932 |
| RRBP1 | ribosome binding protein 1 | -0.0127475 |
| TMSB10 | thymosin beta 10 | -0.0126783 |
| FN1 | fibronectin 1 | -0.0126552 |
| KHSRP | KH-type splicing regulatory protein | -0.012617 |
| MEAF6 | MYST/Esa1-associated factor 6 | -0.0125948 |
| ZNF518A | zinc finger protein 518A | -0.0125166 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0125016 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0124734 |
