| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.348089 |
| FMN1 | formin 1 | 0.159629 |
| FNDC3B | fibronectin type III domain containing 3B | 0.144983 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0972607 |
| NAV2 | neuron navigator 2 | 0.0885863 |
| LDHA | lactate dehydrogenase A | 0.0760246 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0706463 |
| MSN | moesin | 0.0690611 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0633512 |
| PGK1 | phosphoglycerate kinase 1 | 0.0613138 |
| FLNA | filamin A, alpha | 0.0601788 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.060112 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0566514 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0561279 |
| CENPF | centromere protein F, 350/400kDa | 0.0547137 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0537375 |
| ENO1 | enolase 1, (alpha) | 0.0532575 |
| CANX | calnexin | 0.0504008 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0492546 |
| FMNL2 | formin-like 2 | 0.0481481 |
| GOLGA4 | golgin A4 | 0.0481372 |
| SPAG9 | sperm associated antigen 9 | 0.0480684 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0478688 |
| NOTCH2 | notch 2 | 0.0476211 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0468429 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0465196 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0462956 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0446445 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0445824 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0444456 |
| RPL3 | ribosomal protein L3 | 0.04307 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0428773 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0427438 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0426647 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0426626 |
| ICAM1 | intercellular adhesion molecule 1 | 0.042539 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0412225 |
| SETD5 | SET domain containing 5 | 0.0412007 |
| SFTPA2 | surfactant protein A2 | 0.0408625 |
| RTN4 | reticulon 4 | 0.0406509 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0406366 |
| KAZN | kazrin, periplakin interacting protein | 0.040542 |
| TPM3 | tropomyosin 3 | 0.0399723 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.039743 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.038383 |
| ITGB5 | integrin, beta 5 | 0.0381097 |
| ANLN | anillin, actin binding protein | 0.0381029 |
| PMEL | premelanosome protein | 0.03675 |
| ANXA2 | annexin A2 | 0.0362674 |
| PRELID2 | PRELI domain containing 2 | 0.0360849 |
| FRMD5 | FERM domain containing 5 | 0.0358634 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0356234 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0356095 |
| ZNF292 | zinc finger protein 292 | 0.0349857 |
| CLINT1 | clathrin interactor 1 | 0.0349804 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0348177 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0347684 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0344697 |
| HELZ | helicase with zinc finger | 0.0336614 |
| POTEF | POTE ankyrin domain family, member F | 0.0334621 |
| MAP4 | microtubule-associated protein 4 | 0.0331966 |
| EP300 | E1A binding protein p300 | 0.0331916 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0331417 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0331277 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0329619 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0326279 |
| TXNRD1 | thioredoxin reductase 1 | 0.0325307 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0323511 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0323411 |
| MKI67 | marker of proliferation Ki-67 | 0.0319443 |
| MSI2 | musashi RNA-binding protein 2 | 0.031479 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0309662 |
| OGA | O-GlcNAcase | 0.0308282 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0308087 |
| CORO1C | coronin, actin binding protein, 1C | 0.0305485 |
| AFDN | afadin, adherens junction formation factor | 0.0300932 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0300867 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0297038 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0295937 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0293622 |
| RNF145 | ring finger protein 145 | 0.0293107 |
| ANXA5 | annexin A5 | 0.0290838 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0290527 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0287887 |
| CALD1 | caldesmon 1 | 0.0286342 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0285696 |
| ACTN1 | actinin, alpha 1 | 0.0285668 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.028462 |
| PKM | pyruvate kinase, muscle | 0.0283255 |
| YEATS2 | YEATS domain containing 2 | 0.0274521 |
| RHOA | ras homolog family member A | 0.0273148 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0272828 |
| OXSR1 | oxidative stress responsive 1 | 0.0269065 |
| CLIC4 | chloride intracellular channel 4 | 0.0267973 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0267964 |
| MMP12 | matrix metallopeptidase 12 | 0.026702 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0264583 |
| PLEC | plectin | 0.0264223 |
| CCNL1 | cyclin L1 | 0.0264063 |
| RLF | rearranged L-myc fusion | 0.0263899 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.153684 |
| NLGN1 | neuroligin 1 | -0.0957621 |
| TMSB10 | thymosin beta 10 | -0.0866701 |
| RPLP1 | ribosomal protein, large, P1 | -0.0816378 |
| RPL35A | ribosomal protein L35a | -0.0756616 |
| RPS3 | ribosomal protein S3 | -0.0703033 |
| RPL34 | ribosomal protein L34 | -0.051783 |
| FTL | ferritin, light polypeptide | -0.0485758 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0472159 |
| RPS6 | ribosomal protein S6 | -0.0463231 |
| RPL23 | ribosomal protein L23 | -0.0460099 |
| MT1X | metallothionein 1X | -0.0434059 |
| RPL37A | ribosomal protein L37a | -0.0431574 |
| RPS13 | ribosomal protein S13 | -0.0426434 |
| RPLP2 | ribosomal protein, large, P2 | -0.0419134 |
| RPS12 | ribosomal protein S12 | -0.0418279 |
| PTMA | prothymosin, alpha | -0.0412354 |
| RPL31 | ribosomal protein L31 | -0.0400333 |
| RPS21 | ribosomal protein S21 | -0.0393895 |
| RPS23 | ribosomal protein S23 | -0.0387888 |
| RPS29 | ribosomal protein S29 | -0.0373779 |
| VIM | vimentin | -0.0367375 |
| RPL12 | ribosomal protein L12 | -0.0364129 |
| RPL32 | ribosomal protein L32 | -0.0357964 |
| RPL38 | ribosomal protein L38 | -0.0353131 |
| RPS8 | ribosomal protein S8 | -0.0348015 |
| RPS19 | ribosomal protein S19 | -0.0344089 |
| RPS24 | ribosomal protein S24 | -0.0339675 |
| RPS27A | ribosomal protein S27a | -0.0316729 |
| RPL9 | ribosomal protein L9 | -0.0314565 |
| S100A9 | S100 calcium binding protein A9 | -0.0301131 |
| RPL36A | ribosomal protein L36a | -0.0297035 |
| RPL36 | ribosomal protein L36 | -0.029468 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.029339 |
| RPS16 | ribosomal protein S16 | -0.0291353 |
| RPL37 | ribosomal protein L37 | -0.0278616 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0275464 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0273468 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0267935 |
| INTS6 | integrator complex subunit 6 | -0.0256978 |
| RPS14 | ribosomal protein S14 | -0.0250115 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0236623 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0233837 |
| RPL26 | ribosomal protein L26 | -0.0232932 |
| FOXP1 | forkhead box P1 | -0.0231074 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0230292 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.022953 |
| RPS27 | ribosomal protein S27 | -0.0224829 |
| PDE10A | phosphodiesterase 10A | -0.0224031 |
| SEC61G | Sec61 gamma subunit | -0.0222225 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0214101 |
| RPL35 | ribosomal protein L35 | -0.021185 |
| AUTS2 | autism susceptibility candidate 2 | -0.0209157 |
| RPL11 | ribosomal protein L11 | -0.0206239 |
| SP100 | SP100 nuclear antigen | -0.0206209 |
| IFI44L | interferon-induced protein 44-like | -0.0200067 |
| IER3 | immediate early response 3 | -0.0199808 |
| HDAC4 | histone deacetylase 4 | -0.0195809 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0193852 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0193652 |
| LAMTOR5 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 | -0.0192622 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0192265 |
| RPL28 | ribosomal protein L28 | -0.0192043 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0191468 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0189929 |
| RPS15 | ribosomal protein S15 | -0.0187524 |
| RPL27A | ribosomal protein L27a | -0.0187384 |
| PRAME | preferentially expressed antigen in melanoma | -0.0186231 |
| TBCA | tubulin folding cofactor A | -0.018299 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0182053 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0180522 |
| RACK1 | receptor for activated C kinase 1 | -0.0180422 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0178912 |
| EHBP1 | EH domain binding protein 1 | -0.0178451 |
| RPS11 | ribosomal protein S11 | -0.0178111 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0177593 |
| RPS25 | ribosomal protein S25 | -0.0173186 |
| CADM1 | cell adhesion molecule 1 | -0.0171168 |
| ENTHD1 | ENTH domain containing 1 | -0.0170742 |
| RPL5 | ribosomal protein L5 | -0.0170188 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0169519 |
| RPL8 | ribosomal protein L8 | -0.016831 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0166807 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0166622 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0164694 |
| HLA-B | major histocompatibility complex, class I, B | -0.0163216 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0162361 |
| RPS20 | ribosomal protein S20 | -0.0161319 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0159672 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0159434 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0158005 |
| GPATCH2L | G patch domain containing 2-like | -0.0157865 |
| RPL30 | ribosomal protein L30 | -0.0156638 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.015659 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0156058 |
| RIGI | RNA sensor RIG-I | -0.0154716 |
| RPL19 | ribosomal protein L19 | -0.0154072 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.015388 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.0152795 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.015251 |
