| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | 0.197913 |
| FN1 | fibronectin 1 | 0.189387 |
| COL6A3 | collagen, type VI, alpha 3 | 0.120202 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.119937 |
| PDE10A | phosphodiesterase 10A | 0.118401 |
| DST | dystonin | 0.116313 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.114817 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.104713 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.104087 |
| GLIS3 | GLIS family zinc finger 3 | 0.0983965 |
| VCL | vinculin | 0.0964905 |
| MSN | moesin | 0.0925279 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0913794 |
| SMAD3 | SMAD family member 3 | 0.0907957 |
| ATXN1 | ataxin 1 | 0.0898591 |
| TNS3 | tensin 3 | 0.0890528 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0882392 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0875849 |
| BICC1 | BicC family RNA binding protein 1 | 0.0854318 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0832927 |
| VCAN | versican | 0.0807047 |
| HDAC9 | histone deacetylase 9 | 0.0795204 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0780293 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0766963 |
| C3 | complement component 3 | 0.0734461 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0729201 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0718338 |
| JMJD1C | jumonji domain containing 1C | 0.0711133 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0690332 |
| VMP1 | vacuole membrane protein 1 | 0.0676785 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0661799 |
| NAV2 | neuron navigator 2 | 0.0653101 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0642704 |
| MYOF | myoferlin | 0.0630388 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.062363 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.061976 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0596919 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0596282 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0577508 |
| VEGFA | vascular endothelial growth factor A | 0.057264 |
| CD44 | CD44 molecule (Indian blood group) | 0.0572333 |
| NAV1 | neuron navigator 1 | 0.0568971 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0568733 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0567482 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0554439 |
| SEPTIN9 | septin 9 | 0.0548955 |
| EGR1 | early growth response 1 | 0.054833 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0543641 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0519397 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0519277 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0510664 |
| SMYD3 | SET and MYND domain containing 3 | 0.0505534 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0502445 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0497218 |
| FNIP1 | folliculin interacting protein 1 | 0.0495769 |
| RNF213 | ring finger protein 213 | 0.0495119 |
| FLNB | filamin B, beta | 0.0492928 |
| NABP1 | nucleic acid binding protein 1 | 0.0461714 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0451163 |
| CALD1 | caldesmon 1 | 0.0449533 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0447115 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0443762 |
| CADM1 | cell adhesion molecule 1 | 0.0440892 |
| SFTPA2 | surfactant protein A2 | 0.0436212 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0434146 |
| GPC6 | glypican 6 | 0.0432786 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0430099 |
| CDK19 | cyclin-dependent kinase 19 | 0.0427912 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0425856 |
| RAD51B | RAD51 paralog B | 0.042553 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0416615 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0416335 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0408563 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0408189 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.040546 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0402198 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0398739 |
| EGFR | epidermal growth factor receptor | 0.0398535 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0381977 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0374921 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0368641 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0345067 |
| CCNL1 | cyclin L1 | 0.0341206 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0340266 |
| GOLGB1 | golgin B1 | 0.0339729 |
| NDRG1 | N-myc downstream regulated 1 | 0.0339014 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0336916 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0334611 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0332946 |
| CLIC4 | chloride intracellular channel 4 | 0.033121 |
| SDC4 | syndecan 4 | 0.0327947 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0325616 |
| COL5A1 | collagen, type V, alpha 1 | 0.0324989 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0322869 |
| RND3 | Rho family GTPase 3 | 0.0322465 |
| FRMD5 | FERM domain containing 5 | 0.0322115 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.031814 |
| RAI14 | retinoic acid induced 14 | 0.0318065 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0317908 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0316934 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IER3 | immediate early response 3 | -0.0967832 |
| TMSB10 | thymosin beta 10 | -0.09149 |
| VIM | vimentin | -0.0790781 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0701341 |
| RPS24 | ribosomal protein S24 | -0.0583445 |
| FTL | ferritin, light polypeptide | -0.0582886 |
| PTMA | prothymosin, alpha | -0.0512455 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0480706 |
| RPL35A | ribosomal protein L35a | -0.044762 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0428866 |
| RPS27A | ribosomal protein S27a | -0.0400383 |
| RPLP1 | ribosomal protein, large, P1 | -0.0382104 |
| RPL23 | ribosomal protein L23 | -0.0374917 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0373751 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0365429 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.035937 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0347484 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0337847 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0337735 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.033221 |
| WTAP | Wilms tumor 1 associated protein | -0.0313998 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0312531 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0303717 |
| MT2A | metallothionein 2A | -0.0301629 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0292296 |
| RPLP2 | ribosomal protein, large, P2 | -0.0290601 |
| MATR3 | matrin 3 | -0.0273809 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0273095 |
| SRGN | serglycin | -0.0271219 |
| RPL36A | ribosomal protein L36a | -0.0267168 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0265167 |
| ANLN | anillin, actin binding protein | -0.0263878 |
| CENPF | centromere protein F, 350/400kDa | -0.0250277 |
| RPS8 | ribosomal protein S8 | -0.0243118 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0242101 |
| CALR | calreticulin | -0.0239881 |
| UBC | ubiquitin C | -0.0234491 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0233765 |
| RPS23 | ribosomal protein S23 | -0.0227951 |
| RPL34 | ribosomal protein L34 | -0.0222716 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0218713 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0215179 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0210792 |
| RPL32 | ribosomal protein L32 | -0.0208242 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0205895 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0201272 |
| RYBP | RING1 and YY1 binding protein | -0.0200725 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0199569 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0196582 |
| CD63 | CD63 molecule | -0.0194527 |
| RPL31 | ribosomal protein L31 | -0.0192017 |
| RRBP1 | ribosome binding protein 1 | -0.0191553 |
| RPL26 | ribosomal protein L26 | -0.0191235 |
| TKT | transketolase | -0.0191028 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0189613 |
| WDR45B | WD repeat domain 45B | -0.018948 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0187565 |
| AHNAK | AHNAK nucleoprotein | -0.0187159 |
| TPX2 | TPX2, microtubule-associated | -0.0181197 |
| TXNRD1 | thioredoxin reductase 1 | -0.0181191 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.017863 |
| RPS25 | ribosomal protein S25 | -0.017748 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0176619 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0174704 |
| FAM162A | family with sequence similarity 162, member A | -0.0168718 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0167805 |
| PGK1 | phosphoglycerate kinase 1 | -0.01672 |
| PRR11 | proline rich 11 | -0.0166795 |
| HLA-B | major histocompatibility complex, class I, B | -0.0163606 |
| RPL19 | ribosomal protein L19 | -0.0163582 |
| RPL5 | ribosomal protein L5 | -0.0160458 |
| DEK | DEK proto-oncogene | -0.0158779 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0156974 |
| RPL38 | ribosomal protein L38 | -0.0155409 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0155315 |
| NPR2 | natriuretic peptide receptor 2 | -0.0152171 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0151813 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0149081 |
| NUP58 | nucleoporin 58 | -0.0147222 |
| QKI | QKI, KH domain containing, RNA binding | -0.0146984 |
| RPL12 | ribosomal protein L12 | -0.0146825 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0145537 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0144617 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0143859 |
| SPAG9 | sperm associated antigen 9 | -0.0143487 |
| INSIG1 | insulin induced gene 1 | -0.0140569 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0138541 |
| RPL7 | ribosomal protein L7 | -0.013827 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0137453 |
| RPS21 | ribosomal protein S21 | -0.0137016 |
| KIF4A | kinesin family member 4A | -0.0135577 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0135192 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0134618 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0134282 |
| MKI67 | marker of proliferation Ki-67 | -0.013224 |
| CD70 | CD70 molecule | -0.0130821 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0129801 |
| USP3 | ubiquitin specific peptidase 3 | -0.0129328 |
| TTK | TTK protein kinase | -0.0128797 |
| RPS5 | ribosomal protein S5 | -0.0127525 |
