| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.264661 |
| COL1A1 | collagen, type I, alpha 1 | 0.133783 |
| FN1 | fibronectin 1 | 0.128488 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.111305 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.1104 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0949631 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0721643 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0696815 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0691911 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0684597 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0677617 |
| CDH13 | cadherin 13 | 0.0603674 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0582484 |
| ARRDC3 | arrestin domain containing 3 | 0.0577544 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0545114 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0535237 |
| EGFR | epidermal growth factor receptor | 0.0524288 |
| LOXL2 | lysyl oxidase-like 2 | 0.0506757 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0491217 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0490126 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0484089 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0474945 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0452117 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.04451 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0426577 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0425753 |
| MAP1B | microtubule-associated protein 1B | 0.0418853 |
| CALR | calreticulin | 0.0411483 |
| GSE1 | Gse1 coiled-coil protein | 0.040425 |
| ANXA2 | annexin A2 | 0.0390638 |
| NDRG1 | N-myc downstream regulated 1 | 0.0379128 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0378682 |
| SETD5 | SET domain containing 5 | 0.0377436 |
| MSN | moesin | 0.0368822 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0360984 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0346874 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0346531 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.034344 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0341349 |
| FAM13A | family with sequence similarity 13, member A | 0.0339913 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0330823 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0328986 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0328086 |
| FLNA | filamin A, alpha | 0.0324141 |
| SMYD3 | SET and MYND domain containing 3 | 0.0318263 |
| VEGFC | vascular endothelial growth factor C | 0.0317608 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0313904 |
| RLF | rearranged L-myc fusion | 0.0311725 |
| CD44 | CD44 molecule (Indian blood group) | 0.0302208 |
| CAVIN1 | caveolae associated protein 1 | 0.0296265 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0291176 |
| TXNIP | thioredoxin interacting protein | 0.0281023 |
| RNF216 | ring finger protein 216 | 0.0280547 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0280242 |
| EXT1 | exostosin glycosyltransferase 1 | 0.027966 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0279544 |
| FRMD4A | FERM domain containing 4A | 0.0278402 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0276306 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.027411 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0269502 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0268411 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0267066 |
| TPM3 | tropomyosin 3 | 0.0265378 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0261188 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0259048 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0254445 |
| CADM1 | cell adhesion molecule 1 | 0.0253819 |
| OGA | O-GlcNAcase | 0.0253559 |
| RTN4 | reticulon 4 | 0.025075 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0249404 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0248878 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0248757 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.024862 |
| LOC112694756 | uncharaterized LOC112694756 | 0.024676 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0246703 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0245826 |
| MYOF | myoferlin | 0.0243988 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0243198 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0241801 |
| ANO6 | anoctamin 6 | 0.0241189 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0240869 |
| THBS1 | thrombospondin 1 | 0.02397 |
| ANXA5 | annexin A5 | 0.0239501 |
| RBM25 | RNA binding motif protein 25 | 0.0239376 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0237642 |
| LDHA | lactate dehydrogenase A | 0.023654 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.0236471 |
| MYADM | myeloid-associated differentiation marker | 0.0236448 |
| GOLGA4 | golgin A4 | 0.0236243 |
| MEF2A | myocyte enhancer factor 2A | 0.0233919 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0233456 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0232594 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0232054 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0231734 |
| RNF24 | ring finger protein 24 | 0.0231352 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0231131 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0230628 |
| AUTS2 | autism susceptibility candidate 2 | 0.0225305 |
| TPM2 | tropomyosin 2 (beta) | 0.0225091 |
| CTSB | cathepsin B | 0.0224912 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0491239 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0451647 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0443878 |
| TMSB10 | thymosin beta 10 | -0.0422877 |
| AHNAK | AHNAK nucleoprotein | -0.0411897 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0385527 |
| RAI14 | retinoic acid induced 14 | -0.037932 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0377408 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0358752 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0327193 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0327121 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0326605 |
| LOX | lysyl oxidase | -0.0323047 |
| ZNF395 | zinc finger protein 395 | -0.0301125 |
| QKI | QKI, KH domain containing, RNA binding | -0.0295813 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0292527 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0292192 |
| MT2A | metallothionein 2A | -0.0290213 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0286553 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0284554 |
| INHBA | inhibin, beta A | -0.0248522 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0246835 |
| INSIG2 | insulin induced gene 2 | -0.0246481 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0238046 |
| COG6 | component of oligomeric golgi complex 6 | -0.0237452 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0236676 |
| FUS | FUS RNA binding protein | -0.022759 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0225816 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0219096 |
| FAM3C | family with sequence similarity 3, member C | -0.0216278 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0214363 |
| RPL36 | ribosomal protein L36 | -0.0213889 |
| CBX3 | chromobox homolog 3 | -0.0212016 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0209588 |
| INTS6 | integrator complex subunit 6 | -0.0207653 |
| FTL | ferritin, light polypeptide | -0.0207437 |
| COLEC11 | collectin sub-family member 11 | -0.0199827 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0199302 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0199054 |
| UBXN4 | UBX domain protein 4 | -0.0198866 |
| RNF11 | ring finger protein 11 | -0.0198394 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.019808 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0196658 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 | -0.0192573 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0190755 |
| VEGFA | vascular endothelial growth factor A | -0.0190145 |
| TMSB4X | thymosin beta 4, X-linked | -0.0189387 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0188714 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0188707 |
| JAK1 | Janus kinase 1 | -0.0187321 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0186275 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0186132 |
| RPL31 | ribosomal protein L31 | -0.0185315 |
| PI3 | peptidase inhibitor 3, skin-derived | -0.0185211 |
| ETFA | electron-transfer-flavoprotein, alpha polypeptide | -0.0183652 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0182126 |
| TGFB1 | transforming growth factor, beta 1 | -0.0178419 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0177408 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0176582 |
| RIGI | RNA sensor RIG-I | -0.0174962 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0173217 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0173049 |
| RPL34 | ribosomal protein L34 | -0.0172646 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.017026 |
| ZNF800 | zinc finger protein 800 | -0.0169526 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0168156 |
| XBP1 | X-box binding protein 1 | -0.0166712 |
| DMXL1 | Dmx-like 1 | -0.0166513 |
| RYBP | RING1 and YY1 binding protein | -0.0166061 |
| HPCAL1 | hippocalcin-like 1 | -0.0165265 |
| GOLGA3 | golgin A3 | -0.016413 |
| PCED1B | PC-esterase domain containing 1B | -0.0163557 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0162628 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0162546 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0161185 |
| TLE4 | transducin-like enhancer of split 4 | -0.0160957 |
| TBCA | tubulin folding cofactor A | -0.0160829 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0160561 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0160395 |
| ASPH | aspartate beta-hydroxylase | -0.016001 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0158895 |
| RTN3 | reticulon 3 | -0.0158675 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 | -0.015839 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0158065 |
| TPM1 | tropomyosin 1 (alpha) | -0.0157578 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | -0.0157366 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0156897 |
| RPS11 | ribosomal protein S11 | -0.0156644 |
| STC2 | stanniocalcin 2 | -0.0156196 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0155582 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0154066 |
| SRP54 | signal recognition particle 54kDa | -0.0152422 |
| RORA | RAR-related orphan receptor A | -0.0151219 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0150921 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein | -0.0150687 |
| TCF12 | transcription factor 12 | -0.0150158 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0149327 |
| SLC25A51 | solute carrier family 25, member 51 | -0.0148851 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0148841 |
| SMIM14 | small integral membrane protein 14 | -0.0148744 |
