| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0821237 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.074559 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0708975 |
| NAV2 | neuron navigator 2 | 0.0703526 |
| OSMR | oncostatin M receptor | 0.0625375 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0594178 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0544341 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0509651 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.048333 |
| DST | dystonin | 0.0478418 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0474245 |
| ZNF292 | zinc finger protein 292 | 0.0467823 |
| FMNL2 | formin-like 2 | 0.0458532 |
| ATP13A3 | ATPase type 13A3 | 0.0443995 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0435167 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0433181 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.04307 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0421214 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0420686 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0412888 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0410887 |
| MCL1 | myeloid cell leukemia 1 | 0.0406836 |
| PRKCA | protein kinase C, alpha | 0.0405669 |
| ENO1 | enolase 1, (alpha) | 0.0403459 |
| SMAD3 | SMAD family member 3 | 0.0402351 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0401212 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0393581 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0388832 |
| CD44 | CD44 molecule (Indian blood group) | 0.0383346 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0383101 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0383011 |
| CEP250 | centrosomal protein 250kDa | 0.0381512 |
| FLNB | filamin B, beta | 0.0376956 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0371704 |
| MSN | moesin | 0.0369143 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0360701 |
| ASPH | aspartate beta-hydroxylase | 0.0339019 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0337842 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0332497 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0328885 |
| PTK2 | protein tyrosine kinase 2 | 0.0323656 |
| SDC4 | syndecan 4 | 0.0323026 |
| PYGL | phosphorylase, glycogen, liver | 0.0322847 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0318505 |
| RNF213 | ring finger protein 213 | 0.0317851 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0315603 |
| RAD51B | RAD51 paralog B | 0.0314263 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0312784 |
| HJURP | Holliday junction recognition protein | 0.0310695 |
| SMYD3 | SET and MYND domain containing 3 | 0.0309284 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0305296 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0303734 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0303516 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0303162 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0300324 |
| SS18 | synovial sarcoma translocation, chromosome 18 | 0.0300059 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0298865 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0295556 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0294778 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0294291 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0293593 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0291954 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0289493 |
| TPX2 | TPX2, microtubule-associated | 0.0289277 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0285743 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0282736 |
| FLNA | filamin A, alpha | 0.0279639 |
| LDHA | lactate dehydrogenase A | 0.0279149 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0278509 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0277926 |
| ANGPTL4 | angiopoietin-like 4 | 0.0277479 |
| SEPTIN2 | septin 2 | 0.0276252 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0274805 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.027319 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0272698 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0272458 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | 0.027171 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0271697 |
| CDCP1 | CUB domain containing protein 1 | 0.0270871 |
| NXN | nucleoredoxin | 0.0269502 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0268268 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0267273 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0266665 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0265563 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0260504 |
| MYO9B | myosin IXB | 0.0260196 |
| KIAA1328 | KIAA1328 | 0.0259212 |
| NBAS | neuroblastoma amplified sequence | 0.0259049 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0257591 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0257102 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0256015 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0255463 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0251299 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0251239 |
| ABI2 | abl-interactor 2 | 0.0250786 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.0249559 |
| PRKCE | protein kinase C, epsilon | 0.0246479 |
| PDE8A | phosphodiesterase 8A | 0.0246311 |
| TNRC18 | trinucleotide repeat containing 18 | 0.024527 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.02451 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPLP1 | ribosomal protein, large, P1 | -0.0861252 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0807166 |
| MT2A | metallothionein 2A | -0.0683387 |
| TMSB10 | thymosin beta 10 | -0.0666642 |
| VIM | vimentin | -0.0546812 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0530992 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0495018 |
| RPL35A | ribosomal protein L35a | -0.0491233 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0473985 |
| DEK | DEK proto-oncogene | -0.0442226 |
| RPS8 | ribosomal protein S8 | -0.0441468 |
| IER3 | immediate early response 3 | -0.0436776 |
| RPS19 | ribosomal protein S19 | -0.0402529 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0367757 |
| FTL | ferritin, light polypeptide | -0.0361259 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.033955 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0333069 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0329746 |
| RPL32 | ribosomal protein L32 | -0.0326049 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0321763 |
| RPS25 | ribosomal protein S25 | -0.032055 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0314139 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0311389 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0311034 |
| RPL27A | ribosomal protein L27a | -0.0304158 |
| S100A9 | S100 calcium binding protein A9 | -0.029808 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0298019 |
| RACK1 | receptor for activated C kinase 1 | -0.029623 |
| TPI1 | triosephosphate isomerase 1 | -0.0286434 |
| HMGA2 | high mobility group AT-hook 2 | -0.0285128 |
| RPS24 | ribosomal protein S24 | -0.0284845 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.027961 |
| RPS3 | ribosomal protein S3 | -0.0277406 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0276931 |
| B2M | beta-2-microglobulin | -0.0274674 |
| PHIP | pleckstrin homology domain interacting protein | -0.0269606 |
| WBP11 | WW domain binding protein 11 | -0.0267797 |
| BMERB1 | bMERB domain containing 1 | -0.0267223 |
| RPL12 | ribosomal protein L12 | -0.0265126 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0263711 |
| RPS23 | ribosomal protein S23 | -0.0263576 |
| RPL38 | ribosomal protein L38 | -0.0257497 |
| PURA | purine-rich element binding protein A | -0.0255725 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0254821 |
| PTMA | prothymosin, alpha | -0.0254716 |
| TAOK1 | TAO kinase 1 | -0.0252455 |
| OGA | O-GlcNAcase | -0.0252067 |
| POTEF | POTE ankyrin domain family, member F | -0.0249935 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0246148 |
| CLINT1 | clathrin interactor 1 | -0.0244569 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0243715 |
| RPS11 | ribosomal protein S11 | -0.0243071 |
| RPS13 | ribosomal protein S13 | -0.0241201 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0240995 |
| AKAP10 | A kinase (PRKA) anchor protein 10 | -0.0234965 |
| RPL23 | ribosomal protein L23 | -0.0225793 |
| RSRP1 | arginine/serine-rich protein 1 | -0.0224839 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0224783 |
| RPL36AL | ribosomal protein L36a-like | -0.0222517 |
| S100A6 | S100 calcium binding protein A6 | -0.0222351 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit | -0.0221173 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.022007 |
| ATG12 | autophagy related 12 | -0.0216264 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0215177 |
| ATAD1 | ATPase family, AAA domain containing 1 | -0.021451 |
| KLF6 | Kruppel-like factor 6 | -0.021379 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0210926 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0210504 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0209678 |
| KLHL24 | kelch-like family member 24 | -0.0208304 |
| FAM3C | family with sequence similarity 3, member C | -0.0208284 |
| H3-3B | H3.3 histone B | -0.0207475 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0207136 |
| HLA-C | major histocompatibility complex, class I, C | -0.0206867 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0205928 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0205615 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0204326 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0204194 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0203552 |
| RPL6 | ribosomal protein L6 | -0.0201006 |
| RPS6 | ribosomal protein S6 | -0.020079 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0198726 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | -0.0198547 |
| MEF2A | myocyte enhancer factor 2A | -0.019835 |
| TUBA1B | tubulin, alpha 1b | -0.0197971 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0197287 |
| RPS17 | ribosomal protein S17 | -0.0196081 |
| RPL19 | ribosomal protein L19 | -0.0195972 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0195422 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0193927 |
| RPL18 | ribosomal protein L18 | -0.0193554 |
| ZC3H13 | zinc finger CCCH-type containing 13 | -0.0193152 |
| JUND | jun D proto-oncogene | -0.0192395 |
| UBC | ubiquitin C | -0.0191927 |
| RPL8 | ribosomal protein L8 | -0.0190505 |
| IFT20 | intraflagellar transport 20 | -0.0189984 |
| RPL31 | ribosomal protein L31 | -0.0189226 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0188959 |
| GOLT1B | golgi transport 1B | -0.0186726 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0186381 |