| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.180325 |
| HMGA2 | high mobility group AT-hook 2 | 0.123808 |
| NRG1 | neuregulin 1 | 0.112608 |
| GLIS3 | GLIS family zinc finger 3 | 0.104938 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0847383 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0837764 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0608615 |
| ITGA1 | integrin, alpha 1 | 0.0592237 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0518812 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0499671 |
| ASPH | aspartate beta-hydroxylase | 0.0493077 |
| EFNA5 | ephrin-A5 | 0.0487618 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0479867 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.045655 |
| GPC6 | glypican 6 | 0.0434658 |
| STC2 | stanniocalcin 2 | 0.0429845 |
| PRELID2 | PRELI domain containing 2 | 0.0419239 |
| RUNX2 | runt-related transcription factor 2 | 0.0407353 |
| CENPF | centromere protein F, 350/400kDa | 0.0406556 |
| ETV6 | ets variant 6 | 0.0402566 |
| RAI14 | retinoic acid induced 14 | 0.0389405 |
| NRP1 | neuropilin 1 | 0.0387266 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0386536 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0386448 |
| VCL | vinculin | 0.0385831 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0384106 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0379648 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0370469 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.036215 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0343701 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0326193 |
| SMOX | spermine oxidase | 0.0318127 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0318026 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0317244 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0316567 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0313073 |
| AHR | aryl hydrocarbon receptor | 0.030711 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0303133 |
| SQSTM1 | sequestosome 1 | 0.0297074 |
| SYT1 | synaptotagmin I | 0.0296413 |
| VEGFC | vascular endothelial growth factor C | 0.029547 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0292649 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0286364 |
| RAD51B | RAD51 paralog B | 0.0281535 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0280218 |
| OSMR | oncostatin M receptor | 0.0277882 |
| MAP1B | microtubule-associated protein 1B | 0.0275667 |
| DST | dystonin | 0.0269277 |
| TXNIP | thioredoxin interacting protein | 0.0263541 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0262613 |
| MKI67 | marker of proliferation Ki-67 | 0.0262186 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0260121 |
| NAV1 | neuron navigator 1 | 0.0255767 |
| TNS3 | tensin 3 | 0.0249348 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0247148 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0241589 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0239741 |
| PRKCA | protein kinase C, alpha | 0.02382 |
| TNNC1 | troponin C type 1 (slow) | 0.0235661 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0231546 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0231497 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0228849 |
| VEGFA | vascular endothelial growth factor A | 0.0224889 |
| SMAD3 | SMAD family member 3 | 0.0224662 |
| TPR | translocated promoter region, nuclear basket protein | 0.0222858 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0219334 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0219266 |
| ATXN1 | ataxin 1 | 0.0219195 |
| TMEM165 | transmembrane protein 165 | 0.0217297 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0214542 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0212886 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0212402 |
| AFDN | afadin, adherens junction formation factor | 0.0210486 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0209487 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0207242 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.020685 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0205921 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0205105 |
| RNF213 | ring finger protein 213 | 0.0204513 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0204145 |
| ITGB5 | integrin, beta 5 | 0.0199252 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0195659 |
| LOXL2 | lysyl oxidase-like 2 | 0.019288 |
| RASAL2 | RAS protein activator like 2 | 0.0191444 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0190723 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0188986 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0187817 |
| USP34 | ubiquitin specific peptidase 34 | 0.0186658 |
| PLIN2 | perilipin 2 | 0.018627 |
| CALU | calumenin | 0.0186252 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0184716 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0184547 |
| BICC1 | BicC family RNA binding protein 1 | 0.0183012 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0182632 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0182606 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0182407 |
| PCBP3 | poly(rC) binding protein 3 | 0.0181793 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0179709 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0177153 |
| FNIP1 | folliculin interacting protein 1 | 0.0174839 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.137852 |
| MT2A | metallothionein 2A | -0.112995 |
| PTMA | prothymosin, alpha | -0.098521 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0908337 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.068226 |
| TMSB10 | thymosin beta 10 | -0.0634506 |
| RPS27A | ribosomal protein S27a | -0.0549023 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0546953 |
| FTL | ferritin, light polypeptide | -0.0538798 |
| UBC | ubiquitin C | -0.0537784 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0490727 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0444636 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0422282 |
| VIM | vimentin | -0.0412336 |
| IER3 | immediate early response 3 | -0.0393961 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0377615 |
| RPL23 | ribosomal protein L23 | -0.0376655 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0371098 |
| RPS19 | ribosomal protein S19 | -0.0360736 |
| CANX | calnexin | -0.0359585 |
| CALR | calreticulin | -0.0350462 |
| RPL12 | ribosomal protein L12 | -0.0348565 |
| RPL35A | ribosomal protein L35a | -0.0346043 |
| RPS6 | ribosomal protein S6 | -0.0333519 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0333082 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0332699 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.03312 |
| RPS12 | ribosomal protein S12 | -0.0330481 |
| RPL26 | ribosomal protein L26 | -0.0326128 |
| RPS3 | ribosomal protein S3 | -0.0312597 |
| RACK1 | receptor for activated C kinase 1 | -0.0311252 |
| RPL31 | ribosomal protein L31 | -0.0310546 |
| S100A6 | S100 calcium binding protein A6 | -0.0309521 |
| RPL9 | ribosomal protein L9 | -0.0308252 |
| RPL37A | ribosomal protein L37a | -0.0295756 |
| RPS24 | ribosomal protein S24 | -0.0290925 |
| B2M | beta-2-microglobulin | -0.0287117 |
| RPLP1 | ribosomal protein, large, P1 | -0.0286061 |
| RPS23 | ribosomal protein S23 | -0.0284111 |
| RHEB | Ras homolog enriched in brain | -0.0280759 |
| RPS29 | ribosomal protein S29 | -0.0276067 |
| RPS8 | ribosomal protein S8 | -0.0275482 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0263744 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0261762 |
| NDRG1 | N-myc downstream regulated 1 | -0.0258095 |
| S100A10 | S100 calcium binding protein A10 | -0.0257282 |
| RYBP | RING1 and YY1 binding protein | -0.0256516 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.025591 |
| WDR45B | WD repeat domain 45B | -0.0253212 |
| RPS21 | ribosomal protein S21 | -0.0251733 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0248629 |
| RPL34 | ribosomal protein L34 | -0.0243883 |
| RPS27 | ribosomal protein S27 | -0.0237872 |
| RPL19 | ribosomal protein L19 | -0.0237185 |
| RPS25 | ribosomal protein S25 | -0.0237155 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0233608 |
| NOP58 | NOP58 ribonucleoprotein | -0.0230792 |
| RPL36 | ribosomal protein L36 | -0.0230475 |
| OGA | O-GlcNAcase | -0.022507 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0224118 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0223401 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0212611 |
| PKM | pyruvate kinase, muscle | -0.0211424 |
| RPL38 | ribosomal protein L38 | -0.0209319 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0209087 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0206543 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0205846 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0205156 |
| RPLP2 | ribosomal protein, large, P2 | -0.0204952 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0204866 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0204787 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0203081 |
| WTAP | Wilms tumor 1 associated protein | -0.0202409 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.020169 |
| RPS11 | ribosomal protein S11 | -0.0201081 |
| RPL7 | ribosomal protein L7 | -0.0199546 |
| RNF145 | ring finger protein 145 | -0.0199039 |
| MT1X | metallothionein 1X | -0.0194064 |
| FAM13A | family with sequence similarity 13, member A | -0.01937 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0190236 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.018936 |
| RPS5 | ribosomal protein S5 | -0.0189159 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0188088 |
| MATR3 | matrin 3 | -0.0187615 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0186618 |
| SEPTIN7 | septin 7 | -0.0184993 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0183775 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0183742 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0183657 |
| RPL28 | ribosomal protein L28 | -0.01828 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.018205 |
| S100A9 | S100 calcium binding protein A9 | -0.0181946 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0181015 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0180504 |
| HLA-B | major histocompatibility complex, class I, B | -0.0179593 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0178468 |
| RPS20 | ribosomal protein S20 | -0.017741 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0174258 |
| RPL32 | ribosomal protein L32 | -0.0172435 |
| NUP58 | nucleoporin 58 | -0.0172272 |
