| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dimethyl fumarate perturbation in SW480 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Dimethyl fumarate_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.194766 |
| EZR | ezrin | 0.15802 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.125019 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.119008 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.115696 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.109526 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.102085 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0995262 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0904571 |
| ATXN1 | ataxin 1 | 0.0874236 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0869456 |
| RUNX1 | runt-related transcription factor 1 | 0.0836592 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0786657 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0779217 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0778613 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0747075 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0744129 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0715263 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0709101 |
| NAV2 | neuron navigator 2 | 0.0697134 |
| TNS3 | tensin 3 | 0.0682663 |
| KRT8 | keratin 8, type II | 0.0680475 |
| KIZ | kizuna centrosomal protein | 0.0650334 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0639948 |
| DSPP | dentin sialophosphoprotein | 0.0635458 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.062628 |
| ENO1 | enolase 1, (alpha) | 0.0567253 |
| EGR1 | early growth response 1 | 0.0555244 |
| PCBP2 | poly(rC) binding protein 2 | 0.0546911 |
| BCL2L1 | BCL2-like 1 | 0.0539548 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0535916 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0533269 |
| TXNIP | thioredoxin interacting protein | 0.0509894 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0502472 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0501561 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0494982 |
| CENPF | centromere protein F, 350/400kDa | 0.04862 |
| DST | dystonin | 0.0485928 |
| EFNB2 | ephrin-B2 | 0.0463726 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0458323 |
| ANXA2 | annexin A2 | 0.0453039 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0446688 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0442081 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0434935 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0431519 |
| ARF4 | ADP-ribosylation factor 4 | 0.0430015 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0428276 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0424998 |
| ETNK1 | ethanolamine kinase 1 | 0.0415491 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0405326 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0403888 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0402409 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0397221 |
| HDAC8 | histone deacetylase 8 | 0.0390937 |
| SBF2 | SET binding factor 2 | 0.0390527 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0389783 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0389434 |
| HDAC4 | histone deacetylase 4 | 0.0389353 |
| MSN | moesin | 0.0381723 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0378675 |
| RPL3 | ribosomal protein L3 | 0.0377675 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0376421 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0369572 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.036791 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0366313 |
| MCL1 | myeloid cell leukemia 1 | 0.0361247 |
| RAD51B | RAD51 paralog B | 0.0360842 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0360357 |
| PGK1 | phosphoglycerate kinase 1 | 0.0359403 |
| CDK19 | cyclin-dependent kinase 19 | 0.0359096 |
| CMIP | c-Maf inducing protein | 0.0358189 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0358176 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0357682 |
| NONO | non-POU domain containing, octamer-binding | 0.0357486 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0355492 |
| OXR1 | oxidation resistance 1 | 0.0353323 |
| ITGA6 | integrin, alpha 6 | 0.0352728 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0351748 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0351641 |
| SVIL | supervillin | 0.035137 |
| TNS4 | tensin 4 | 0.0350547 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0348497 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0345071 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0339915 |
| VMP1 | vacuole membrane protein 1 | 0.0339597 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0338444 |
| SYT1 | synaptotagmin I | 0.0338333 |
| POTEF | POTE ankyrin domain family, member F | 0.0338028 |
| ANO6 | anoctamin 6 | 0.0337433 |
| ABHD2 | abhydrolase domain containing 2 | 0.0336882 |
| PRELID2 | PRELI domain containing 2 | 0.0334765 |
| WWOX | WW domain containing oxidoreductase | 0.033266 |
| ACTN1 | actinin, alpha 1 | 0.0331784 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0330251 |
| PROX1 | prospero homeobox 1 | 0.0329902 |
| ZNF638 | zinc finger protein 638 | 0.0328723 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0325054 |
| ZNRF3 | zinc and ring finger 3 | 0.0322635 |
| EMP1 | epithelial membrane protein 1 | 0.0322203 |
| VGLL4 | vestigial-like family member 4 | 0.0320649 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.105926 |
| TMSB10 | thymosin beta 10 | -0.0742614 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0615417 |
| CCND1 | cyclin D1 | -0.060708 |
| RPS24 | ribosomal protein S24 | -0.056933 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0539011 |
| RPL35A | ribosomal protein L35a | -0.0492116 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0428911 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0394106 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0383341 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0367152 |
| MT2A | metallothionein 2A | -0.0352759 |
| RPL36A | ribosomal protein L36a | -0.0335604 |
| AHNAK | AHNAK nucleoprotein | -0.033288 |
| IER3 | immediate early response 3 | -0.0323126 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0320117 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.029538 |
| RPLP1 | ribosomal protein, large, P1 | -0.0294279 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0290264 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0287638 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0282146 |
| NOP56 | NOP56 ribonucleoprotein | -0.0274071 |
| TFRC | transferrin receptor | -0.026297 |
| RPS23 | ribosomal protein S23 | -0.0261902 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0261082 |
| RPL38 | ribosomal protein L38 | -0.0253207 |
| HMGB1 | high mobility group box 1 | -0.0244779 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0237117 |
| RPS27A | ribosomal protein S27a | -0.0236602 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0229368 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0226412 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0220727 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0212828 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0212073 |
| EPCAM | epithelial cell adhesion molecule | -0.020957 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0209305 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0204725 |
| FTL | ferritin, light polypeptide | -0.0203408 |
| NPR2 | natriuretic peptide receptor 2 | -0.0200183 |
| RPS21 | ribosomal protein S21 | -0.0194103 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0194001 |
| CBFB | core-binding factor, beta subunit | -0.0192412 |
| RPLP2 | ribosomal protein, large, P2 | -0.0187052 |
| RPL31 | ribosomal protein L31 | -0.0184387 |
| RPL34 | ribosomal protein L34 | -0.0184297 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0183468 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.018296 |
| TMSB4X | thymosin beta 4, X-linked | -0.0182691 |
| RPL32 | ribosomal protein L32 | -0.0181971 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.017945 |
| RPL6 | ribosomal protein L6 | -0.017645 |
| RPS13 | ribosomal protein S13 | -0.0174201 |
| KHSRP | KH-type splicing regulatory protein | -0.017363 |
| MTAP | methylthioadenosine phosphorylase | -0.017304 |
| ABI2 | abl-interactor 2 | -0.0166876 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0166669 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0165773 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0164664 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0164259 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0163232 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.016268 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0161578 |
| MT1X | metallothionein 1X | -0.0158102 |
| UBE2I | ubiquitin-conjugating enzyme E2I | -0.0157646 |
| RBP1 | retinol binding protein 1, cellular | -0.0156781 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0154671 |
| CALR | calreticulin | -0.0153959 |
| HPCAL1 | hippocalcin-like 1 | -0.0153103 |
| RPS19 | ribosomal protein S19 | -0.015284 |
| RPS25 | ribosomal protein S25 | -0.0152529 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0152135 |
| ABLIM1 | actin binding LIM protein 1 | -0.0150116 |
| SLC38A1 | solute carrier family 38, member 1 | -0.014988 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | -0.0148778 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0148408 |
| VKORC1L1 | vitamin K epoxide reductase complex, subunit 1-like 1 | -0.0147032 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0143401 |
| RPS29 | ribosomal protein S29 | -0.014276 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0141111 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0139852 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0138355 |
| TRIM56 | tripartite motif containing 56 | -0.0138131 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0137476 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 | -0.0136833 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0136585 |
| IPO7 | importin 7 | -0.0136551 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | -0.0135618 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0135276 |
| NOP58 | NOP58 ribonucleoprotein | -0.013516 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | -0.0135087 |
| RPL19 | ribosomal protein L19 | -0.0134748 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0134501 |
| PARK7 | parkinson protein 7 | -0.0134422 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0134146 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | -0.0134093 |
| AK1 | adenylate kinase 1 | -0.0133718 |
| CUL1 | cullin 1 | -0.0133177 |
| TUBA1B | tubulin, alpha 1b | -0.0131792 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0131697 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | -0.0131413 |