| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dinaciclib perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dinaciclib_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KLF6 | Kruppel-like factor 6 | 0.0601051 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0434786 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0423039 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0400756 |
| TGM2 | transglutaminase 2 | 0.0368994 |
| SET | SET nuclear proto-oncogene | 0.0323327 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0293211 |
| TPM3 | tropomyosin 3 | 0.0275895 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0262732 |
| HDGF | hepatoma-derived growth factor | 0.0254001 |
| FLII | flightless I homolog (Drosophila) | 0.0226856 |
| CALR | calreticulin | 0.0214301 |
| CANX | calnexin | 0.0202085 |
| FLNA | filamin A, alpha | 0.0193322 |
| POTEF | POTE ankyrin domain family, member F | 0.0175365 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0175121 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0173897 |
| TEX14 | testis expressed 14 | 0.0173282 |
| RPS23 | ribosomal protein S23 | 0.016342 |
| DEK | DEK proto-oncogene | 0.0161509 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0160712 |
| ANXA1 | annexin A1 | 0.016061 |
| PTMA | prothymosin, alpha | 0.0157764 |
| GSTP1 | glutathione S-transferase pi 1 | 0.0154778 |
| YBX1 | Y box binding protein 1 | 0.0154534 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0149088 |
| DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.0148477 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.0147781 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0145962 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0144116 |
| TPM2 | tropomyosin 2 (beta) | 0.0143518 |
| RPS4X | ribosomal protein S4, X-linked | 0.0142587 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0142021 |
| CCND1 | cyclin D1 | 0.0141246 |
| RPL11 | ribosomal protein L11 | 0.0137298 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0137262 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0136708 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.0136577 |
| TMEM167A | transmembrane protein 167A | 0.0135071 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0134732 |
| HYOU1 | hypoxia up-regulated 1 | 0.0132633 |
| CDC37 | cell division cycle 37 | 0.0132081 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.013111 |
| HELLS | helicase, lymphoid-specific | 0.0129819 |
| RPL37 | ribosomal protein L37 | 0.0128695 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0128379 |
| RPL3 | ribosomal protein L3 | 0.0126834 |
| TFDP1 | transcription factor Dp-1 | 0.0125898 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0124569 |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | 0.0123184 |
| GHITM | growth hormone inducible transmembrane protein | 0.0122278 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0120402 |
| RPS6 | ribosomal protein S6 | 0.0118963 |
| RANBP1 | RAN binding protein 1 | 0.0118921 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.011821 |
| SBDS | Shwachman-Bodian-Diamond syndrome | 0.0117511 |
| RPL8 | ribosomal protein L8 | 0.0117043 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0116683 |
| NUCB2 | nucleobindin 2 | 0.011636 |
| RPL19 | ribosomal protein L19 | 0.0116014 |
| HLA-A | major histocompatibility complex, class I, A | 0.011598 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0113443 |
| MYOF | myoferlin | 0.0112979 |
| DSG2 | desmoglein 2 | 0.0111854 |
| RPS3 | ribosomal protein S3 | 0.0110895 |
| IER3 | immediate early response 3 | 0.0110512 |
| EBNA1BP2 | EBNA1 binding protein 2 | 0.0110168 |
| ACLY | ATP citrate lyase | 0.0110096 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0109892 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0109852 |
| STIP1 | stress-induced phosphoprotein 1 | 0.010969 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.0108518 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0107472 |
| CALD1 | caldesmon 1 | 0.0106933 |
| DSTN | destrin (actin depolymerizing factor) | 0.0106875 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0106388 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | 0.0106183 |
| SKA2 | spindle and kinetochore associated complex subunit 2 | 0.0106048 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0105486 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0104697 |
| KARS1 | lysyl-tRNA synthetase 1 | 0.0104433 |
| SEPTIN11 | septin 11 | 0.0103747 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0103721 |
| PABPC4 | poly(A) binding protein, cytoplasmic 4 (inducible form) | 0.0103403 |
| MOB1A | MOB kinase activator 1A | 0.0103207 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.010296 |
| RNF103-CHMP3 | RNF103-CHMP3 readthrough | 0.0102394 |
| PLEC | plectin | 0.0102387 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0101781 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 0.0101546 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0100374 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0100005 |
| NHP2 | NHP2 ribonucleoprotein | 0.00985047 |
| JUN | jun proto-oncogene | 0.00977988 |
| WDR74 | WD repeat domain 74 | 0.00973538 |
| RBM17 | RNA binding motif protein 17 | 0.0096257 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.00960715 |
| SNF8 | SNF8, ESCRT-II complex subunit | 0.00959834 |
| SEC11C | SEC11 homolog C (S. cerevisiae) | 0.0095633 |
| GOLGA2 | golgin A2 | 0.0095523 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.168265 |
| AREG | amphiregulin | -0.155016 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.140864 |
| NLGN1 | neuroligin 1 | -0.11604 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0929609 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0822035 |
| ANKRD12 | ankyrin repeat domain 12 | -0.079046 |
| TMSB10 | thymosin beta 10 | -0.0731936 |
| DST | dystonin | -0.0607436 |
| USP34 | ubiquitin specific peptidase 34 | -0.0576047 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0572562 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0523324 |
| JMJD1C | jumonji domain containing 1C | -0.0521713 |
| VMP1 | vacuole membrane protein 1 | -0.048343 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0459372 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0450025 |
| TENM3 | teneurin transmembrane protein 3 | -0.0405905 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0399944 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0390359 |
| PCDH7 | protocadherin 7 | -0.0388962 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0382681 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.037135 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0368514 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.036455 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0357377 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0353698 |
| EHBP1 | EH domain binding protein 1 | -0.0349563 |
| NHSL1 | NHS-like 1 | -0.0348658 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0344417 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0336557 |
| FBXO11 | F-box protein 11 | -0.0332915 |
| MMP12 | matrix metallopeptidase 12 | -0.033064 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0326073 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0325904 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0324933 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0322993 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0321216 |
| ACTG1 | actin gamma 1 | -0.0321031 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0314191 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0312952 |
| TMEM41B | transmembrane protein 41B | -0.0310552 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0303683 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0302957 |
| NEBL | nebulette | -0.0300827 |
| TXNRD1 | thioredoxin reductase 1 | -0.0300172 |
| MGAT4C | MGAT4 family, member C | -0.0296826 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0292602 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0286579 |
| RBM39 | RNA binding motif protein 39 | -0.0282778 |
| ZNF638 | zinc finger protein 638 | -0.0280753 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0280238 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0279934 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0278335 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0276693 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0274521 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0273158 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0265775 |
| EXOC6B | exocyst complex component 6B | -0.0264558 |
| MED13L | mediator complex subunit 13-like | -0.0260987 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0260957 |
| CEP192 | centrosomal protein 192kDa | -0.0258327 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0253812 |
| PDGFC | platelet derived growth factor C | -0.0252666 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0251764 |
| LMO7 | LIM domain 7 | -0.0246709 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0246401 |
| DTNA | dystrobrevin, alpha | -0.0245753 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0244894 |
| RSF1 | remodeling and spacing factor 1 | -0.0241219 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0240813 |
| RBM25 | RNA binding motif protein 25 | -0.0240329 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0238349 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0233514 |
| NF1 | neurofibromin 1 | -0.0232289 |
| SMYD3 | SET and MYND domain containing 3 | -0.0228979 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0228111 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0227172 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0227108 |
| ERBIN | erbb2 interacting protein | -0.0226198 |
| PTK2 | protein tyrosine kinase 2 | -0.022365 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.0221766 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0221375 |
| BCHE | butyrylcholinesterase | -0.0220038 |
| IPO7 | importin 7 | -0.0219609 |
| TPI1 | triosephosphate isomerase 1 | -0.0218476 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0217541 |
| HDAC9 | histone deacetylase 9 | -0.0217519 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.021644 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0214908 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0214683 |
| EPHA6 | EPH receptor A6 | -0.0213696 |
| EDARADD | EDAR-associated death domain | -0.0213078 |
| MTAP | methylthioadenosine phosphorylase | -0.0212642 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0212333 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0212317 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0211948 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0210666 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0210639 |
| RAB10 | RAB10, member RAS oncogene family | -0.0207958 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0207348 |
