| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dinaciclib perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dinaciclib_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| APOB | apolipoprotein B | 0.265505 |
| C3 | complement component 3 | 0.117114 |
| TF | transferrin | 0.0896012 |
| CDC7 | cell division cycle 7 | 0.0850634 |
| PEG10 | paternally expressed 10 | 0.0822915 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0805916 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0774331 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0647287 |
| FN1 | fibronectin 1 | 0.0643736 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0601856 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0588555 |
| IGF2 | insulin-like growth factor 2 | 0.0490165 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.0467286 |
| LYZ | lysozyme | 0.0418818 |
| TRIM26 | tripartite motif containing 26 | 0.0413866 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.0383907 |
| SELENOP | selenoprotein P | 0.0365229 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.0341523 |
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.0338104 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0334191 |
| POTEF | POTE ankyrin domain family, member F | 0.0326765 |
| MATN3 | matrilin 3 | 0.0325464 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0322718 |
| PCBP2 | poly(rC) binding protein 2 | 0.0319203 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0316775 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0306145 |
| RPL3 | ribosomal protein L3 | 0.0302792 |
| KRT18 | keratin 18, type I | 0.029214 |
| CPE | carboxypeptidase E | 0.0289323 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0283887 |
| RPL11 | ribosomal protein L11 | 0.0283084 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0283044 |
| SET | SET nuclear proto-oncogene | 0.0264267 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.0263007 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0261694 |
| APOA1 | apolipoprotein A-I | 0.025895 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0249072 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0229624 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.0229301 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | 0.0228308 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0225732 |
| TPM3 | tropomyosin 3 | 0.022146 |
| LAMB1 | laminin, beta 1 | 0.0215729 |
| DHFR | dihydrofolate reductase | 0.021359 |
| APOE | apolipoprotein E | 0.0206949 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0202615 |
| FABP1 | fatty acid binding protein 1, liver | 0.020225 |
| CALR | calreticulin | 0.0194198 |
| KRT8 | keratin 8, type II | 0.0191915 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0189689 |
| FGA | fibrinogen alpha chain | 0.0189608 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0189073 |
| RPS4X | ribosomal protein S4, X-linked | 0.0188956 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0182132 |
| CBX3 | chromobox homolog 3 | 0.0180889 |
| SEPTIN9 | septin 9 | 0.0178028 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0177829 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0174096 |
| EPCAM | epithelial cell adhesion molecule | 0.0169967 |
| GHITM | growth hormone inducible transmembrane protein | 0.0169391 |
| DEK | DEK proto-oncogene | 0.0165955 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0165547 |
| CCND1 | cyclin D1 | 0.016275 |
| DCDC2 | doublecortin domain containing 2 | 0.0161837 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.015918 |
| KIF1C | kinesin family member 1C | 0.0157847 |
| CDK6 | cyclin-dependent kinase 6 | 0.0154586 |
| GSN | gelsolin | 0.0153958 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0152896 |
| QPRT | quinolinate phosphoribosyltransferase | 0.0150086 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0150028 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0148345 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0147365 |
| CLU | clusterin | 0.0146791 |
| FRMD5 | FERM domain containing 5 | 0.014551 |
| PTMS | parathymosin | 0.0143024 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0142037 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0141741 |
| APOA2 | apolipoprotein A-II | 0.0140352 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0139742 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0139724 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0139226 |
| BPIFB2 | BPI fold containing family B, member 2 | 0.0138877 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0137157 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0133762 |
| KIF5B | kinesin family member 5B | 0.013298 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0132506 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0131973 |
| CCT3 | chaperonin containing TCP1, subunit 3 (gamma) | 0.0131802 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0131745 |
| FGG | fibrinogen gamma chain | 0.0130901 |
| AHSG | alpha-2-HS-glycoprotein | 0.013068 |
| SLC16A13 | solute carrier family 16, member 13 | 0.0128805 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | 0.012874 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0128281 |
| ZC3H3 | zinc finger CCCH-type containing 3 | 0.0127474 |
| STMN1 | stathmin 1 | 0.01269 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0126809 |
| PCM1 | pericentriolar material 1 | 0.0126661 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.0126468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.24615 |
| FNDC3B | fibronectin type III domain containing 3B | -0.157248 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.135191 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.112477 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.109791 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.10274 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.100717 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0964801 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0835764 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0824654 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0750632 |
| SLC38A2 | solute carrier family 38, member 2 | -0.074629 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0742695 |
| ATXN1 | ataxin 1 | -0.0735975 |
| EXT1 | exostosin glycosyltransferase 1 | -0.073122 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0703282 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0656731 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0627134 |
| SDC4 | syndecan 4 | -0.0622697 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0619773 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0618359 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0600905 |
| ENO1 | enolase 1, (alpha) | -0.0586336 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0577612 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0572827 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0558673 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0545804 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0539642 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0533964 |
| ASPH | aspartate beta-hydroxylase | -0.0530821 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.052986 |
| PHF3 | PHD finger protein 3 | -0.0522352 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0519752 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0514779 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0509721 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0478966 |
| SVIL | supervillin | -0.0478674 |
| JMJD1C | jumonji domain containing 1C | -0.0468825 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.046756 |
| AFDN | afadin, adherens junction formation factor | -0.0467474 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0460805 |
| PLIN2 | perilipin 2 | -0.0454119 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0451088 |
| FAM107B | family with sequence similarity 107, member B | -0.0449765 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0447559 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0447329 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0447163 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0446052 |
| MT2A | metallothionein 2A | -0.0435409 |
| PEG3 | paternally expressed 3 | -0.0427165 |
| DTNA | dystrobrevin, alpha | -0.0419781 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0407392 |
| STK17A | serine/threonine kinase 17a | -0.0396703 |
| MCL1 | myeloid cell leukemia 1 | -0.0394296 |
| RPL37A | ribosomal protein L37a | -0.0386572 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0385575 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0384824 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0383679 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0380939 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0377275 |
| GPC6 | glypican 6 | -0.03769 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0375544 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0373437 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0373115 |
| KLF6 | Kruppel-like factor 6 | -0.0372932 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0369469 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0368787 |
| KIF21A | kinesin family member 21A | -0.0368564 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0368435 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.036601 |
| INTS6 | integrator complex subunit 6 | -0.0364114 |
| ZNF292 | zinc finger protein 292 | -0.0357594 |
| SPAG9 | sperm associated antigen 9 | -0.0356966 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0355502 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0355267 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0349647 |
| IER3 | immediate early response 3 | -0.0348908 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0348019 |
| ARFGEF3 | ARFGEF family member 3 | -0.0347479 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0345682 |
| LDHA | lactate dehydrogenase A | -0.0345525 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0340769 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0336261 |
| EPAS1 | endothelial PAS domain protein 1 | -0.033508 |
| DENND4A | DENN/MADD domain containing 4A | -0.0333779 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0330123 |
| RYBP | RING1 and YY1 binding protein | -0.0326265 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0322772 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0320624 |
| H1-0 | H1.0 linker histone | -0.0318442 |
| SESTD1 | SEC14 and spectrin domains 1 | -0.0315729 |
| UBC | ubiquitin C | -0.0315712 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0313951 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0310921 |
| KIAA1217 | KIAA1217 | -0.0303234 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0300532 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0299883 |
| SMAD3 | SMAD family member 3 | -0.0299827 |
| JAK1 | Janus kinase 1 | -0.0298999 |
| DOCK4 | dedicator of cytokinesis 4 | -0.029796 |
