| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dinaciclib perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dinaciclib_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.146493 |
| FN1 | fibronectin 1 | 0.105892 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0911591 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0833845 |
| COL5A2 | collagen, type V, alpha 2 | 0.0727375 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0718391 |
| PTMA | prothymosin, alpha | 0.069083 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0661509 |
| IER2 | immediate early response 2 | 0.0633014 |
| IER3 | immediate early response 3 | 0.0632191 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0554832 |
| YBX1 | Y box binding protein 1 | 0.055361 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0520097 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0501744 |
| RPL19 | ribosomal protein L19 | 0.0501617 |
| TEX14 | testis expressed 14 | 0.0493682 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0475416 |
| FTL | ferritin, light polypeptide | 0.0464562 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.045918 |
| RPS6 | ribosomal protein S6 | 0.0456542 |
| JUN | jun proto-oncogene | 0.0446158 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0434648 |
| RPS12 | ribosomal protein S12 | 0.0425966 |
| TMSB10 | thymosin beta 10 | 0.0413855 |
| EGR1 | early growth response 1 | 0.0409283 |
| RPS4X | ribosomal protein S4, X-linked | 0.0405941 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0394372 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0353287 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0350974 |
| RPLP2 | ribosomal protein, large, P2 | 0.0350648 |
| RPL11 | ribosomal protein L11 | 0.0348371 |
| TXNRD1 | thioredoxin reductase 1 | 0.0346269 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0341897 |
| RPL37A | ribosomal protein L37a | 0.0336053 |
| SET | SET nuclear proto-oncogene | 0.0330374 |
| HEATR1 | HEAT repeat containing 1 | 0.0329254 |
| ZC3H3 | zinc finger CCCH-type containing 3 | 0.0325284 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0322868 |
| ASPH | aspartate beta-hydroxylase | 0.0321106 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0315726 |
| POTEF | POTE ankyrin domain family, member F | 0.0315003 |
| KLF6 | Kruppel-like factor 6 | 0.0309999 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.030908 |
| LAMB1 | laminin, beta 1 | 0.0306944 |
| TPM3 | tropomyosin 3 | 0.0301511 |
| RPLP1 | ribosomal protein, large, P1 | 0.0298753 |
| B2M | beta-2-microglobulin | 0.0295224 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.0294479 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0287695 |
| TMSB4X | thymosin beta 4, X-linked | 0.0280444 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0279289 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.0267929 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0264209 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0261316 |
| PRDX1 | peroxiredoxin 1 | 0.0257614 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0255011 |
| RPL35 | ribosomal protein L35 | 0.0250561 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0249801 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0249454 |
| KIAA0825 | KIAA0825 | 0.0248381 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0242179 |
| GDA | guanine deaminase | 0.024063 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0236439 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0235971 |
| TBXT | T-box transcription factor T | 0.023285 |
| RPS2 | ribosomal protein S2 | 0.0228524 |
| RPS19 | ribosomal protein S19 | 0.0226809 |
| CTSL | cathepsin L | 0.0219865 |
| LDHB | lactate dehydrogenase B | 0.0219367 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0218583 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0217998 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0217715 |
| PNN | pinin, desmosome associated protein | 0.0216408 |
| ENO1 | enolase 1, (alpha) | 0.0213896 |
| HDGF | hepatoma-derived growth factor | 0.0212713 |
| RASAL2 | RAS protein activator like 2 | 0.0212325 |
| RPS27A | ribosomal protein S27a | 0.0210055 |
| KRT18 | keratin 18, type I | 0.0208717 |
| CDK6 | cyclin-dependent kinase 6 | 0.02084 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0205544 |
| CLU | clusterin | 0.0202386 |
| RPS17 | ribosomal protein S17 | 0.0201154 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0201127 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0200679 |
| RANBP1 | RAN binding protein 1 | 0.0200629 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0199778 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0198056 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.0197102 |
| SFTPA2 | surfactant protein A2 | 0.0196673 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0194594 |
| RPS3 | ribosomal protein S3 | 0.0194442 |
| RPS21 | ribosomal protein S21 | 0.0194 |
| ETV3 | ets variant 3 | 0.0190378 |
| UBC | ubiquitin C | 0.0183536 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0182428 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0180725 |
| PFN1 | profilin 1 | 0.0179486 |
| S100A6 | S100 calcium binding protein A6 | 0.0179103 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0179002 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0177812 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EFNA5 | ephrin-A5 | -0.134146 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104712 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0763368 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0739753 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0665411 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0605297 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0590341 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0539489 |
| VCL | vinculin | -0.0509326 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0506334 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0501617 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0496152 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0471778 |
| AUTS2 | autism susceptibility candidate 2 | -0.0455471 |
| KYNU | kynureninase | -0.045214 |
| NDRG1 | N-myc downstream regulated 1 | -0.0438779 |
| PCBP3 | poly(rC) binding protein 3 | -0.0425818 |
| PDE10A | phosphodiesterase 10A | -0.040644 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0403943 |
| INTS6 | integrator complex subunit 6 | -0.0390639 |
| DST | dystonin | -0.0384387 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0375514 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0358267 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0354312 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0344915 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0332094 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0316709 |
| CDH13 | cadherin 13 | -0.0310984 |
| PYGL | phosphorylase, glycogen, liver | -0.0310739 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0308887 |
| NBEAL1 | neurobeachin-like 1 | -0.0308771 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0307949 |
| DENND1A | DENN/MADD domain containing 1A | -0.0307577 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0305921 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0305908 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0301315 |
| PRELID2 | PRELI domain containing 2 | -0.0300163 |
| RAD51B | RAD51 paralog B | -0.0299731 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0295474 |
| SMAD2 | SMAD family member 2 | -0.029517 |
| USP34 | ubiquitin specific peptidase 34 | -0.0292904 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0292204 |
| FNIP1 | folliculin interacting protein 1 | -0.0285592 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0281385 |
| MT2A | metallothionein 2A | -0.0269442 |
| FLNB | filamin B, beta | -0.0261892 |
| MORF4L2 | mortality factor 4 like 2 | -0.0261075 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0254069 |
| LDHA | lactate dehydrogenase A | -0.0249121 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0244852 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0242151 |
| HDAC4 | histone deacetylase 4 | -0.024154 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0239023 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0237857 |
| FMNL2 | formin-like 2 | -0.023715 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0236731 |
| GLRX | glutaredoxin (thioltransferase) | -0.0231832 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.022992 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0229371 |
| GPC6 | glypican 6 | -0.0228899 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0228505 |
| CTBP2 | C-terminal binding protein 2 | -0.0224098 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0223341 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0222134 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0220749 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0217968 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0216535 |
| MYOF | myoferlin | -0.0215452 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0212409 |
| COPA | coatomer protein complex, subunit alpha | -0.0212364 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0207584 |
| CEP350 | centrosomal protein 350kDa | -0.0205919 |
| ATXN1 | ataxin 1 | -0.020566 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.020516 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0204575 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0202764 |
| CCDC88A | coiled-coil domain containing 88A | -0.0200896 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0200103 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0197204 |
| FBXO11 | F-box protein 11 | -0.0196914 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0196352 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0196183 |
| JMJD1C | jumonji domain containing 1C | -0.0195015 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.019216 |
| CDK13 | cyclin-dependent kinase 13 | -0.0190695 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0189852 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0188736 |
| USP53 | ubiquitin specific peptidase 53 | -0.0188075 |
| OGA | O-GlcNAcase | -0.0186178 |
| BMERB1 | bMERB domain containing 1 | -0.0184081 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0183897 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0183798 |
| STC1 | stanniocalcin 1 | -0.0183541 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.018319 |
| ZNF638 | zinc finger protein 638 | -0.018297 |
| DNER | delta/notch-like EGF repeat containing | -0.0182885 |
| OXSR1 | oxidative stress responsive 1 | -0.0181901 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0178462 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -0.0175444 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0174734 |
