| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dinaciclib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dinaciclib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.163164 |
| VIM | vimentin | 0.136479 |
| COL11A1 | collagen, type XI, alpha 1 | 0.133492 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0987026 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0928459 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.092533 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0890182 |
| PTMA | prothymosin, alpha | 0.0806641 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0688594 |
| COL1A2 | collagen, type I, alpha 2 | 0.060669 |
| SNX6 | sorting nexin 6 | 0.0600779 |
| ITGAV | integrin, alpha V | 0.059966 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0568755 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0530111 |
| TMSB4X | thymosin beta 4, X-linked | 0.0519196 |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.0501245 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0496315 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.049351 |
| CADM2 | cell adhesion molecule 2 | 0.0481255 |
| RPS4X | ribosomal protein S4, X-linked | 0.0458247 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0449133 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0435751 |
| ANXA1 | annexin A1 | 0.0433429 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0432273 |
| CYB5D2 | cytochrome b5 domain containing 2 | 0.0426418 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0423618 |
| THBS1 | thrombospondin 1 | 0.041106 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0403428 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0402768 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0397235 |
| POTEF | POTE ankyrin domain family, member F | 0.0392143 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0390314 |
| SFRP4 | secreted frizzled-related protein 4 | 0.0388621 |
| RPS2 | ribosomal protein S2 | 0.0379265 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0378339 |
| RAI1 | retinoic acid induced 1 | 0.0373906 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0371309 |
| LARP1 | La ribonucleoprotein domain family, member 1 | 0.0365295 |
| XIAP | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | 0.0363288 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0354113 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0353347 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0352347 |
| SET | SET nuclear proto-oncogene | 0.0347185 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0343524 |
| RPS6 | ribosomal protein S6 | 0.034246 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0341355 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.033891 |
| NTM | neurotrimin | 0.0338374 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0331452 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0330163 |
| RPL23 | ribosomal protein L23 | 0.0328648 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0324486 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0320856 |
| TUBA1B | tubulin, alpha 1b | 0.0307576 |
| RPL11 | ribosomal protein L11 | 0.0305119 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0302763 |
| TPM3 | tropomyosin 3 | 0.0302723 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0302229 |
| WASF2 | WAS protein family, member 2 | 0.0297884 |
| RPS8 | ribosomal protein S8 | 0.02958 |
| TEX14 | testis expressed 14 | 0.029574 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.029356 |
| HLA-C | major histocompatibility complex, class I, C | 0.0291322 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0289148 |
| FBL | fibrillarin | 0.0289013 |
| KIF5B | kinesin family member 5B | 0.0285698 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0283448 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0282421 |
| PKM | pyruvate kinase, muscle | 0.0281472 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0280573 |
| CBX3 | chromobox homolog 3 | 0.0280536 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 | 0.0278933 |
| RPS27A | ribosomal protein S27a | 0.0278126 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.027549 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0274072 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0273372 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0272968 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0272315 |
| EZR | ezrin | 0.0266798 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0265321 |
| RPL37A | ribosomal protein L37a | 0.0265012 |
| HMCN1 | hemicentin 1 | 0.0263212 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | 0.0260761 |
| CAVIN1 | caveolae associated protein 1 | 0.0257078 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0255398 |
| RPL31 | ribosomal protein L31 | 0.0252402 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.025147 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0250718 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0250639 |
| PEG10 | paternally expressed 10 | 0.0248526 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0246726 |
| CACYBP | calcyclin binding protein | 0.0246341 |
| SSRP1 | structure specific recognition protein 1 | 0.0243187 |
| UBTF | upstream binding transcription factor, RNA polymerase I | 0.024208 |
| LDHB | lactate dehydrogenase B | 0.0240876 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.0238169 |
| RPS11 | ribosomal protein S11 | 0.0238049 |
| ACTG1 | actin gamma 1 | 0.0237349 |
| FUS | FUS RNA binding protein | 0.0236059 |
| RPL26 | ribosomal protein L26 | 0.0235662 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | -0.10553 |
| ZNF292 | zinc finger protein 292 | -0.0900331 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0584183 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0567616 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0557534 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0515701 |
| PDGFC | platelet derived growth factor C | -0.0500817 |
| COL5A2 | collagen, type V, alpha 2 | -0.0498386 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0451626 |
| FBXO11 | F-box protein 11 | -0.0450557 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0449244 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0436906 |
| FOXP2 | forkhead box P2 | -0.0411151 |
| PTK2 | protein tyrosine kinase 2 | -0.0405978 |
| USP3 | ubiquitin specific peptidase 3 | -0.0405279 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0404511 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0404444 |
| RASAL2 | RAS protein activator like 2 | -0.0399378 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0384382 |
| HDAC9 | histone deacetylase 9 | -0.038134 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0381224 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0379405 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0378716 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | -0.0376497 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0365035 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0362398 |
| MTF2 | metal response element binding transcription factor 2 | -0.0358049 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0355292 |
| RHEB | Ras homolog enriched in brain | -0.0340863 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0330194 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0322584 |
| RLF | rearranged L-myc fusion | -0.0320695 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0317185 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0313947 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.031271 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0311992 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0308648 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0307137 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.030349 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0300309 |
| WDR43 | WD repeat domain 43 | -0.0291685 |
| UTRN | utrophin | -0.0289362 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0284757 |
| H1-0 | H1.0 linker histone | -0.0284737 |
| PHF3 | PHD finger protein 3 | -0.0281282 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0280316 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0277497 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0271286 |
| CRY1 | cryptochrome circadian clock 1 | -0.0270492 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0269303 |
| ZNF217 | zinc finger protein 217 | -0.0267638 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0263791 |
| MED13L | mediator complex subunit 13-like | -0.0263245 |
| RBM33 | RNA binding motif protein 33 | -0.0263067 |
| PHIP | pleckstrin homology domain interacting protein | -0.0262994 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0261728 |
| SCFD1 | sec1 family domain containing 1 | -0.0261637 |
| PRKD1 | protein kinase D1 | -0.0257327 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0255804 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0255673 |
| GOLGA4 | golgin A4 | -0.0255533 |
| FOXJ3 | forkhead box J3 | -0.0255335 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0254955 |
| SIK3 | SIK family kinase 3 | -0.0252767 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.0252572 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0249649 |
| RBM39 | RNA binding motif protein 39 | -0.024709 |
| IGF1R | insulin-like growth factor 1 receptor | -0.024684 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0245448 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0245124 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0245053 |
| FAM171B | family with sequence similarity 171, member B | -0.0244806 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.024416 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0244153 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0243681 |
| MYOF | myoferlin | -0.0243356 |
| CDC73 | cell division cycle 73 | -0.0238549 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0238437 |
| USP53 | ubiquitin specific peptidase 53 | -0.0238056 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0237696 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0237633 |
| EVI5 | ecotropic viral integration site 5 | -0.0234068 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0232838 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0228625 |
| MEMO1 | mediator of cell motility 1 | -0.0226416 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0226131 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0224579 |
| HDAC2 | histone deacetylase 2 | -0.0221538 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0221402 |
| NUP58 | nucleoporin 58 | -0.0221253 |
| SLMAP | sarcolemma associated protein | -0.0219044 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0218886 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0216888 |
| NPR2 | natriuretic peptide receptor 2 | -0.0216803 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0216492 |
| ENO1 | enolase 1, (alpha) | -0.0216388 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0215189 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0214157 |
| RYBP | RING1 and YY1 binding protein | -0.0213971 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0213801 |
