| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Dinaciclib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Dinaciclib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.217085 |
| THBS1 | thrombospondin 1 | 0.153575 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.124147 |
| POTEF | POTE ankyrin domain family, member F | 0.0880617 |
| FLNA | filamin A, alpha | 0.0878559 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0807565 |
| TPM4 | tropomyosin 4 | 0.0640666 |
| RPS4X | ribosomal protein S4, X-linked | 0.0631363 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0598005 |
| DEK | DEK proto-oncogene | 0.054513 |
| VIM | vimentin | 0.0531071 |
| RPS6 | ribosomal protein S6 | 0.0522434 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0516481 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0482764 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0476787 |
| CALR | calreticulin | 0.0460947 |
| TMSB4X | thymosin beta 4, X-linked | 0.0460826 |
| PTMA | prothymosin, alpha | 0.0455271 |
| HLA-B | major histocompatibility complex, class I, B | 0.0402363 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.040172 |
| ACTG1 | actin gamma 1 | 0.0397847 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0388186 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0375512 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0372814 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.036941 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0364254 |
| TPM1 | tropomyosin 1 (alpha) | 0.0358989 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0355053 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0353341 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0343427 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0337764 |
| RPL11 | ribosomal protein L11 | 0.033697 |
| MSN | moesin | 0.0336542 |
| KRT18 | keratin 18, type I | 0.0333626 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0328175 |
| FN1 | fibronectin 1 | 0.0326178 |
| CANX | calnexin | 0.0314318 |
| ANXA2 | annexin A2 | 0.0314311 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0308993 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0303489 |
| RPS8 | ribosomal protein S8 | 0.0302767 |
| RPL19 | ribosomal protein L19 | 0.0293631 |
| ENO1 | enolase 1, (alpha) | 0.0290111 |
| SET | SET nuclear proto-oncogene | 0.0289165 |
| RPS24 | ribosomal protein S24 | 0.0278617 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.026954 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0257114 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0253591 |
| RPS12 | ribosomal protein S12 | 0.0249655 |
| YBX1 | Y box binding protein 1 | 0.0249069 |
| TEX14 | testis expressed 14 | 0.024721 |
| DSTN | destrin (actin depolymerizing factor) | 0.0246143 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0242518 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0235798 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0235029 |
| CALD1 | caldesmon 1 | 0.0229574 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0227888 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0227328 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0226796 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0225487 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0225332 |
| KRT8 | keratin 8, type II | 0.0225087 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0224527 |
| TPM3 | tropomyosin 3 | 0.0222202 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0220828 |
| COL1A2 | collagen, type I, alpha 2 | 0.0216735 |
| SFTPA2 | surfactant protein A2 | 0.0215462 |
| RPLP0 | ribosomal protein, large, P0 | 0.0212134 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.02097 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0209025 |
| AHNAK | AHNAK nucleoprotein | 0.0204586 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0204193 |
| RPS2 | ribosomal protein S2 | 0.0202761 |
| PLEC | plectin | 0.0200488 |
| DST | dystonin | 0.0199699 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0198608 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0198032 |
| RPL26 | ribosomal protein L26 | 0.0197715 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0197415 |
| CALU | calumenin | 0.019707 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0195134 |
| FSTL1 | follistatin-like 1 | 0.0193534 |
| CAVIN1 | caveolae associated protein 1 | 0.0193263 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.0185916 |
| TUBA1B | tubulin, alpha 1b | 0.0185441 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0185173 |
| VCAN | versican | 0.0185097 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0183542 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0183216 |
| HMGA2 | high mobility group AT-hook 2 | 0.0178086 |
| CNN3 | calponin 3, acidic | 0.0178079 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0177804 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0172091 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0171074 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.01692 |
| RPL5 | ribosomal protein L5 | 0.0168551 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0166766 |
| CTSB | cathepsin B | 0.0166531 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0166459 |
| ASPH | aspartate beta-hydroxylase | 0.0163109 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0752521 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0729377 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0721817 |
| PDE10A | phosphodiesterase 10A | -0.0518071 |
| ZNF292 | zinc finger protein 292 | -0.0513606 |
| CADM1 | cell adhesion molecule 1 | -0.0479738 |
| NDRG1 | N-myc downstream regulated 1 | -0.0448815 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.043384 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0405748 |
| NAV2 | neuron navigator 2 | -0.0362046 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0346173 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0340928 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0337583 |
| VEGFA | vascular endothelial growth factor A | -0.033667 |
| FRMD4A | FERM domain containing 4A | -0.0325463 |
| SPAG9 | sperm associated antigen 9 | -0.0320078 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0319541 |
| JMJD1C | jumonji domain containing 1C | -0.031559 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0307353 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0290318 |
| ADM | adrenomedullin | -0.0280069 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0276942 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.027678 |
| HELZ | helicase with zinc finger | -0.0274053 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0268926 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0266438 |
| QKI | QKI, KH domain containing, RNA binding | -0.0261077 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0256943 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0250898 |
| WTAP | Wilms tumor 1 associated protein | -0.0249102 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0248189 |
| ATXN1 | ataxin 1 | -0.0247974 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0241692 |
| SETD5 | SET domain containing 5 | -0.024086 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.023938 |
| TNS3 | tensin 3 | -0.0238745 |
| ATP13A3 | ATPase type 13A3 | -0.0237735 |
| RBM39 | RNA binding motif protein 39 | -0.0236255 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0231622 |
| SMAD3 | SMAD family member 3 | -0.0229713 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0228756 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0227628 |
| OGA | O-GlcNAcase | -0.0224884 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0221224 |
| CCNL1 | cyclin L1 | -0.0221181 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0215574 |
| GOLGA4 | golgin A4 | -0.0213192 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0212643 |
| HDAC9 | histone deacetylase 9 | -0.0212489 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0212101 |
| FNIP1 | folliculin interacting protein 1 | -0.0210315 |
| FOXO3 | forkhead box O3 | -0.0209664 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0207922 |
| IER3 | immediate early response 3 | -0.0199198 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0198731 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0197717 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0189108 |
| AFF4 | AF4/FMR2 family, member 4 | -0.018759 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0187034 |
| SBF2 | SET binding factor 2 | -0.0185948 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.018579 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0184094 |
| PHF21A | PHD finger protein 21A | -0.0182596 |
| KIF13A | kinesin family member 13A | -0.0181676 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0180925 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0178805 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0176828 |
| FMNL2 | formin-like 2 | -0.0176779 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0176132 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0174632 |
| TXNIP | thioredoxin interacting protein | -0.0174156 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0170047 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0169884 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0168787 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.01661 |
| RLF | rearranged L-myc fusion | -0.0165907 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0165088 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0161968 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0160919 |
| PHIP | pleckstrin homology domain interacting protein | -0.0160833 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0160719 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0160296 |
| KLF6 | Kruppel-like factor 6 | -0.0160151 |
| ARRDC3 | arrestin domain containing 3 | -0.0160104 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0159952 |
| TNIP1 | TNFAIP3 interacting protein 1 | -0.0159905 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0159826 |
| ZNF207 | zinc finger protein 207 | -0.0159781 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.01587 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.015648 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0156231 |
| ERBIN | erbb2 interacting protein | -0.0155861 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0152307 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0150008 |
| MYOF | myoferlin | -0.014946 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0148345 |
| UBC | ubiquitin C | -0.0148249 |
| TAPBP | TAP binding protein (tapasin) | -0.0147904 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0146977 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0145076 |
