| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/5280363 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in Dinoprost relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 2.48 |
| SBSN | suprabasin | 1.99 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 1.89 |
| SH3BP5L | SH3-binding domain protein 5-like | 0.65 |
| KLHL15 | kelch-like family member 15 | 0.63 |
| TPGS1 | tubulin polyglutamylase complex subunit 1 | 0.61 |
| FBXW2 | F-box and WD repeat domain containing 2 | 0.58 |
| AKNA | AT-hook transcription factor | 0.56 |
| SLC38A1 | solute carrier family 38, member 1 | 0.53 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.51 |
| AGTRAP | angiotensin II receptor-associated protein | 0.5 |
| TSPAN31 | tetraspanin 31 | 0.46 |
| RUFY3 | RUN and FYVE domain containing 3 | 0.46 |
| MT1L | metallothionein 1L (gene/pseudogene) | 0.45 |
| ALDH1L2 | aldehyde dehydrogenase 1 family, member L2 | 0.45 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.45 |
| SPEG | SPEG complex locus | 0.44 |
| PEX13 | peroxisomal biogenesis factor 13 | 0.44 |
| CASTOR2 | cytosolic arginine sensor for mTORC1 subunit 2 | 0.43 |
| AMPD1 | adenosine monophosphate deaminase 1 | 0.42 |
| MROH6 | maestro heat-like repeat family member 6 | 0.42 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.42 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.41 |
| PXYLP1 | 2-phosphoxylose phosphatase 1 | 0.41 |
| ZDHHC8 | zinc finger, DHHC-type containing 8 | 0.41 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 | 0.4 |
| LRFN1 | leucine rich repeat and fibronectin type III domain containing 1 | 0.4 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H | 0.4 |
| ACD | adrenocortical dysplasia homolog (mouse) | 0.39 |
| LAMA2 | laminin, alpha 2 | 0.39 |
| ZBED6 | zinc finger, BED-type containing 6 | 0.38 |
| USP31 | ubiquitin specific peptidase 31 | 0.37 |
| ZNF267 | zinc finger protein 267 | 0.37 |
| B4GALT3 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 | 0.36 |
| DCLRE1C | DNA cross-link repair 1C | 0.36 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.36 |
| PRKCQ | protein kinase C, theta | 0.36 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 | 0.36 |
| NLRC3 | NLR family, CARD domain containing 3 | 0.36 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.35 |
| LRRC28 | leucine rich repeat containing 28 | 0.35 |
| TPM1 | tropomyosin 1 (alpha) | 0.35 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.35 |
| STXBP6 | syntaxin binding protein 6 (amisyn) | 0.33 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.32 |
| PDIK1L | PDLIM1 interacting kinase 1 like | 0.32 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | 0.32 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) | 0.32 |
| PDE5A | phosphodiesterase 5A, cGMP-specific | 0.32 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.32 |
| CDCA4 | cell division cycle associated 4 | 0.31 |
| DOP1A | DOP1 leucine zipper like protein A | 0.31 |
| MEF2A | myocyte enhancer factor 2A | 0.31 |
| ZNF888 | zinc finger protein 888 | 0.3 |
| TMEM98 | transmembrane protein 98 | 0.29 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.29 |
| TMEM135 | transmembrane protein 135 | 0.29 |
| KLHL29 | kelch-like family member 29 | 0.29 |
| PIGU | phosphatidylinositol glycan anchor biosynthesis, class U | 0.29 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.29 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.29 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.28 |
| KRTCAP3 | keratinocyte associated protein 3 | 0.28 |
| ATF1 | activating transcription factor 1 | 0.28 |
| CNOT7 | CCR4-NOT transcription complex, subunit 7 | 0.28 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.28 |
| TELO2 | telomere maintenance 2 | 0.28 |
| GPRASP2 | G protein-coupled receptor associated sorting protein 2 | 0.28 |
| NRBP2 | nuclear receptor binding protein 2 | 0.28 |
| CCDC85B | coiled-coil domain containing 85B | 0.28 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.27 |
| TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) | 0.27 |
| CEP104 | centrosomal protein 104kDa | 0.27 |
| MZT2B | mitotic spindle organizing protein 2B | 0.27 |
| CCAR2 | cell cycle and apoptosis regulator 2 | 0.27 |
| ASTE1 | asteroid homolog 1 (Drosophila) | 0.27 |
| SMCR8 | Smith-Magenis syndrome chromosome region, candidate 8 | 0.27 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 | 0.27 |
| DDN | dendrin | 0.27 |
| SCG2 | secretogranin II | 0.26 |
| WDR60 | WD repeat domain 60 | 0.26 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 | 0.26 |
| ZNF628 | zinc finger protein 628 | 0.26 |
| TTC14 | tetratricopeptide repeat domain 14 | 0.26 |
| PITX1 | paired-like homeodomain 1 | 0.26 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.26 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 | 0.26 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | 0.26 |
| DES | desmin | 0.26 |
| ERICH5 | glutamate-rich 5 | 0.25 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 | 0.25 |
| ALG10B | ALG10B, alpha-1,2-glucosyltransferase | 0.25 |
| BOD1 | biorientation of chromosomes in cell division 1 | 0.25 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.25 |
| COL6A3 | collagen, type VI, alpha 3 | 0.25 |
| SIKE1 | suppressor of IKBKE 1 | 0.25 |
| KMT5C | lysine methyltransferase 5C | 0.25 |
| ATL1 | atlastin GTPase 1 | 0.24 |
| C12ORF4 | chromosome 12 open reading frame 4 | 0.24 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.87 |
| SRD5A3 | steroid 5 alpha-reductase 3 | -0.68 |
| SEPTIN7 | septin 7 | -0.61 |
| LSM10 | LSM10, U7 small nuclear RNA associated | -0.6 |
| FGB | fibrinogen beta chain | -0.58 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase | -0.52 |
| TWF1 | twinfilin actin binding protein 1 | -0.51 |
| FAM122A | family with sequence similarity 122A | -0.45 |
| ADSS1 | adenylosuccinate synthase 1 | -0.45 |
| SLC35F3 | solute carrier family 35, member F3 | -0.45 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 | -0.44 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 | -0.43 |
| RPE | ribulose-5-phosphate-3-epimerase | -0.42 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.41 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.4 |
| LGALSL | lectin, galactoside-binding-like | -0.38 |
| TM7SF3 | transmembrane 7 superfamily member 3 | -0.37 |
| HTT | huntingtin | -0.37 |
| ANGPTL4 | angiopoietin-like 4 | -0.37 |
| MIEN1 | migration and invasion enhancer 1 | -0.35 |
| ZXDC | ZXD family zinc finger C | -0.35 |
| AP1S3 | adaptor-related protein complex 1, sigma 3 subunit | -0.34 |
| HOXB7 | homeobox B7 | -0.34 |
| SYNE4 | spectrin repeat containing, nuclear envelope family member 4 | -0.34 |
| HRH1 | histamine receptor H1 | -0.33 |
| POMT1 | protein-O-mannosyltransferase 1 | -0.33 |
| EGR1 | early growth response 1 | -0.33 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.33 |
| IFI30 | interferon, gamma-inducible protein 30 | -0.32 |
| PARD6A | par-6 family cell polarity regulator alpha | -0.32 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.31 |
| ZNF780A | zinc finger protein 780A | -0.3 |
| MANEAL | mannosidase, endo-alpha-like | -0.3 |
| MERTK | MER proto-oncogene, tyrosine kinase | -0.3 |
| SLC35B1 | solute carrier family 35, member B1 | -0.29 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.29 |
| PRXL2A | peroxiredoxin like 2A | -0.29 |
| AIF1L | allograft inflammatory factor 1-like | -0.29 |
| ZBTB4 | zinc finger and BTB domain containing 4 | -0.28 |
| CST6 | cystatin E/M | -0.28 |
| CYB5R2 | cytochrome b5 reductase 2 | -0.27 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -0.27 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.27 |
| GPN2 | GPN-loop GTPase 2 | -0.26 |
| ACTBL2 | actin, beta-like 2 | -0.26 |
| METTL22 | methyltransferase like 22 | -0.26 |
| FAM110C | family with sequence similarity 110, member C | -0.26 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.25 |
| ATP5F1D | ATP synthase F1 subunit delta | -0.25 |
| MFAP3 | microfibrillar-associated protein 3 | -0.25 |
| C6ORF47 | chromosome 6 open reading frame 47 | -0.25 |
| PTRHD1 | peptidyl-tRNA hydrolase domain containing 1 | -0.25 |
| UBQLN2 | ubiquilin 2 | -0.25 |
| HM13 | histocompatibility (minor) 13 | -0.24 |
| IL10RB | interleukin 10 receptor, beta | -0.24 |
| KIAA0753 | KIAA0753 | -0.24 |
| ZNF823 | zinc finger protein 823 | -0.24 |
| FAM53C | family with sequence similarity 53, member C | -0.24 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -0.24 |
| XBP1 | X-box binding protein 1 | -0.23 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.23 |
| TMEM63A | transmembrane protein 63A | -0.23 |
| ARSB | arylsulfatase B | -0.23 |
| PALM | paralemmin | -0.23 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | -0.23 |
| POLH | polymerase (DNA directed), eta | -0.23 |
| MPHOSPH9 | M-phase phosphoprotein 9 | -0.23 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.22 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 | -0.22 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.22 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.22 |
| PDZD11 | PDZ domain containing 11 | -0.22 |
| MYOM2 | myomesin 2 | -0.22 |
| RAB19 | RAB19, member RAS oncogene family | -0.21 |
| ALKBH5 | AlkB family member 5, RNA demethylase | -0.21 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 | -0.21 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | -0.21 |
| GID4 | GID complex subunit 4 | -0.21 |
| PLEK2 | pleckstrin 2 | -0.21 |
| TET2 | tet methylcytosine dioxygenase 2 | -0.21 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.21 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | -0.21 |
| SLC39A3 | solute carrier family 39 (zinc transporter), member 3 | -0.21 |
| CHRD | chordin | -0.21 |
| PEX5 | peroxisomal biogenesis factor 5 | -0.21 |
| PSMG2 | proteasome (prosome, macropain) assembly chaperone 2 | -0.21 |
| ING4 | inhibitor of growth family, member 4 | -0.2 |
| DCDC1 | doublecortin domain containing 1 | -0.2 |
| ATXN7L3B | ataxin 7-like 3B | -0.2 |
| EXT1 | exostosin glycosyltransferase 1 | -0.2 |
| LYSMD3 | LysM, putative peptidoglycan-binding, domain containing 3 | -0.2 |
| ANKRD40 | ankyrin repeat domain 40 | -0.2 |
| ATG4D | autophagy related 4D, cysteine peptidase | -0.2 |
| CLTA | clathrin, light chain A | -0.2 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.19 |
| MLXIPL | MLX interacting protein-like | -0.19 |
| ZNF76 | zinc finger protein 76 | -0.19 |
| FSIP2 | fibrous sheath interacting protein 2 | -0.19 |
| DOLK | dolichol kinase | -0.19 |
| CCHCR1 | coiled-coil alpha-helical rod protein 1 | -0.18 |
