| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diphenhydramine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Diphenhydramine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.303665 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.15652 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.147601 |
| FBN1 | fibrillin 1 | 0.129151 |
| CD44 | CD44 molecule (Indian blood group) | 0.121692 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.114199 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.109996 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.106983 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0990324 |
| B2M | beta-2-microglobulin | 0.0947872 |
| MT2A | metallothionein 2A | 0.0897549 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0828812 |
| MYOF | myoferlin | 0.0789748 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0778453 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.075441 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.073706 |
| TMSB4X | thymosin beta 4, X-linked | 0.0710304 |
| FLNB | filamin B, beta | 0.0662621 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0656623 |
| COL3A1 | collagen, type III, alpha 1 | 0.0623724 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0622742 |
| LOXL2 | lysyl oxidase-like 2 | 0.061723 |
| THBS2 | thrombospondin 2 | 0.0607909 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.05931 |
| CTSB | cathepsin B | 0.0572203 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0569845 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0554719 |
| SFTPA2 | surfactant protein A2 | 0.0548326 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0533092 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0531941 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0526289 |
| PRELID2 | PRELI domain containing 2 | 0.0495152 |
| COL1A2 | collagen, type I, alpha 2 | 0.0489325 |
| ARRDC3 | arrestin domain containing 3 | 0.0474909 |
| ANXA2 | annexin A2 | 0.046281 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.046089 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0436545 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0436119 |
| APP | amyloid beta (A4) precursor protein | 0.0429999 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0417284 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0408588 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0407687 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0403344 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0402469 |
| STC1 | stanniocalcin 1 | 0.0402051 |
| FLNA | filamin A, alpha | 0.0399471 |
| PGK1 | phosphoglycerate kinase 1 | 0.0398753 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.038525 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0384693 |
| NAV1 | neuron navigator 1 | 0.0384232 |
| TPM3 | tropomyosin 3 | 0.0373785 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0369394 |
| CANX | calnexin | 0.0365882 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0359336 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0356924 |
| DST | dystonin | 0.0356433 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0353005 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0344774 |
| ANO6 | anoctamin 6 | 0.0344516 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0341833 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.033557 |
| CALR | calreticulin | 0.0334503 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0333797 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0322537 |
| LAMB1 | laminin, beta 1 | 0.0321556 |
| CLU | clusterin | 0.0321312 |
| PTMA | prothymosin, alpha | 0.0316915 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | 0.0313211 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0309369 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0307099 |
| TLN1 | talin 1 | 0.030494 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0304134 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0302551 |
| ADAR | adenosine deaminase, RNA-specific | 0.0301686 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0289569 |
| ENO1 | enolase 1, (alpha) | 0.0281533 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.027938 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0274928 |
| TDRD7 | tudor domain containing 7 | 0.0273216 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0269141 |
| RAI1 | retinoic acid induced 1 | 0.0268914 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0263553 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0259704 |
| SBF2 | SET binding factor 2 | 0.0259549 |
| COL5A2 | collagen, type V, alpha 2 | 0.0259334 |
| RPS2 | ribosomal protein S2 | 0.0258381 |
| SP3 | Sp3 transcription factor | 0.0255516 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0254525 |
| LDHA | lactate dehydrogenase A | 0.0253509 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0252945 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0249476 |
| C1D | C1D nuclear receptor corepressor | 0.0249359 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0248266 |
| OPTN | optineurin | 0.0247414 |
| RNF213 | ring finger protein 213 | 0.0245497 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0245225 |
| XPO1 | exportin 1 | 0.0244306 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0244236 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0243003 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0238633 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.248399 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.108933 |
| NDRG1 | N-myc downstream regulated 1 | -0.0817649 |
| CDH13 | cadherin 13 | -0.0796015 |
| LOX | lysyl oxidase | -0.0768009 |
| TMSB10 | thymosin beta 10 | -0.0614358 |
| PODXL | podocalyxin-like | -0.0581613 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0568039 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0551116 |
| PLAT | plasminogen activator, tissue | -0.051807 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0503561 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0500788 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0476413 |
| CD99 | CD99 molecule | -0.0463323 |
| TAOK1 | TAO kinase 1 | -0.0456485 |
| VIM | vimentin | -0.0442093 |
| TAGLN2 | transgelin 2 | -0.0434358 |
| FN1 | fibronectin 1 | -0.0421589 |
| COPA | coatomer protein complex, subunit alpha | -0.0416326 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0409207 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0406484 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0384334 |
| TAPBP | TAP binding protein (tapasin) | -0.0379698 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0371942 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0371421 |
| S100A6 | S100 calcium binding protein A6 | -0.0364057 |
| BSG | basigin (Ok blood group) | -0.0363934 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0353547 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0344818 |
| INSIG1 | insulin induced gene 1 | -0.033818 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0335953 |
| S100A10 | S100 calcium binding protein A10 | -0.0335864 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0330364 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0325015 |
| POTEF | POTE ankyrin domain family, member F | -0.0299296 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0295033 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0288673 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0283183 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0279931 |
| CDK13 | cyclin-dependent kinase 13 | -0.0279233 |
| EGFR | epidermal growth factor receptor | -0.027825 |
| ACTG1 | actin gamma 1 | -0.0277828 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0277591 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0277536 |
| SRPK2 | SRSF protein kinase 2 | -0.0272793 |
| CCND1 | cyclin D1 | -0.0272517 |
| SUCNR1 | succinate receptor 1 | -0.0270733 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0264236 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.025973 |
| CYTH3 | cytohesin 3 | -0.0259301 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0259114 |
| FBXO11 | F-box protein 11 | -0.0258243 |
| PFN1 | profilin 1 | -0.025743 |
| INTS6 | integrator complex subunit 6 | -0.0257284 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.025603 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0254802 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0251786 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.025051 |
| BPTF | bromodomain PHD finger transcription factor | -0.0249103 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0245809 |
| HLA-B | major histocompatibility complex, class I, B | -0.0245299 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0244988 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0244035 |
| RASAL2 | RAS protein activator like 2 | -0.0233898 |
| MAP1B | microtubule-associated protein 1B | -0.0233791 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | -0.0233772 |
| MSI2 | musashi RNA-binding protein 2 | -0.0232785 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.023 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0228159 |
| MAP4 | microtubule-associated protein 4 | -0.0225082 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0224205 |
| PARD3 | par-3 family cell polarity regulator | -0.02212 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.022104 |
| JAZF1 | JAZF zinc finger 1 | -0.0217664 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0217007 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0216389 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | -0.0215742 |
| ZNF207 | zinc finger protein 207 | -0.0214192 |
| TMEM263 | transmembrane protein 263 | -0.0213638 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0213638 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0209183 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0207954 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.020676 |
| USP34 | ubiquitin specific peptidase 34 | -0.0204843 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0204213 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0203411 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0202888 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.020074 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0199821 |
| GLG1 | golgi glycoprotein 1 | -0.0199436 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0197984 |
| FADS2 | fatty acid desaturase 2 | -0.019624 |
| TUBB | tubulin, beta class I | -0.0194314 |
| SYT1 | synaptotagmin I | -0.019278 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0192564 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.019138 |
| GNAS | GNAS complex locus | -0.0191362 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0190737 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0190587 |
| EXOC6B | exocyst complex component 6B | -0.0190193 |
