| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diphenhydramine perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Diphenhydramine_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.217102 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.180471 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.165548 |
| NRG1 | neuregulin 1 | 0.158047 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.126592 |
| MEIS2 | Meis homeobox 2 | 0.124692 |
| LSAMP | limbic system-associated membrane protein | 0.120313 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.10381 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0979269 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0882603 |
| TRIB2 | tribbles pseudokinase 2 | 0.0793994 |
| FAM13A | family with sequence similarity 13, member A | 0.0786016 |
| RNF213 | ring finger protein 213 | 0.0780256 |
| DST | dystonin | 0.0738898 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0736812 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0713895 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0688918 |
| FMN1 | formin 1 | 0.0675101 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0669038 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0636784 |
| MAP1B | microtubule-associated protein 1B | 0.061403 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0596599 |
| PCDH9 | protocadherin 9 | 0.0568836 |
| DPH6 | diphthamine biosynthesis 6 | 0.0564975 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0556587 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0554563 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.054561 |
| NREP | neuronal regeneration related protein | 0.0540116 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0524559 |
| CENPF | centromere protein F, 350/400kDa | 0.0508687 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0491521 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0489816 |
| ASPH | aspartate beta-hydroxylase | 0.0485646 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0476355 |
| MEF2A | myocyte enhancer factor 2A | 0.0459486 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0448344 |
| SYT1 | synaptotagmin I | 0.0447349 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0441187 |
| RAD51B | RAD51 paralog B | 0.0434658 |
| ZNF292 | zinc finger protein 292 | 0.0434365 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0433216 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0418144 |
| RGS4 | regulator of G-protein signaling 4 | 0.0414789 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0399586 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | 0.0397793 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0389412 |
| COL3A1 | collagen, type III, alpha 1 | 0.0384794 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0383102 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0381674 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0378349 |
| PCBP2 | poly(rC) binding protein 2 | 0.0377177 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0375509 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0371789 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0366014 |
| LPIN1 | lipin 1 | 0.0364225 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0364066 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0361283 |
| CTSB | cathepsin B | 0.0355404 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0352214 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0347969 |
| KLHL13 | kelch-like family member 13 | 0.0337816 |
| ANGPT1 | angiopoietin 1 | 0.033635 |
| EXOC4 | exocyst complex component 4 | 0.0331842 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0329871 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0327571 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0326356 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0321006 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0316792 |
| DNM3 | dynamin 3 | 0.0313498 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0309729 |
| ADAR | adenosine deaminase, RNA-specific | 0.0305664 |
| ENO1 | enolase 1, (alpha) | 0.0305594 |
| PRKCA | protein kinase C, alpha | 0.0304512 |
| VEGFA | vascular endothelial growth factor A | 0.0302932 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0300695 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.029836 |
| AHR | aryl hydrocarbon receptor | 0.0295772 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0293182 |
| GLI3 | GLI family zinc finger 3 | 0.0292898 |
| SET | SET nuclear proto-oncogene | 0.0289887 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0289 |
| FRMD6 | FERM domain containing 6 | 0.0288237 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0286029 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0285289 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0285221 |
| PRKCE | protein kinase C, epsilon | 0.0283027 |
| DNMBP | dynamin binding protein | 0.0282472 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0281638 |
| MSI2 | musashi RNA-binding protein 2 | 0.028108 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0280545 |
| MYO6 | myosin VI | 0.0280139 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0277762 |
| RALYL | RALY RNA binding protein-like | 0.0275509 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0274761 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0270842 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0270249 |
| SLFN5 | schlafen family member 5 | 0.0265842 |
| AUTS2 | autism susceptibility candidate 2 | 0.0263993 |
| SP100 | SP100 nuclear antigen | 0.0260707 |
| SCG2 | secretogranin II | 0.0259401 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.273949 |
| IGF2 | insulin-like growth factor 2 | -0.151228 |
| ACTG1 | actin gamma 1 | -0.0826246 |
| VCL | vinculin | -0.0534696 |
| RPL38 | ribosomal protein L38 | -0.0534608 |
| RPL34 | ribosomal protein L34 | -0.0517313 |
| RPL35A | ribosomal protein L35a | -0.0502955 |
| RPL19 | ribosomal protein L19 | -0.0493188 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0488253 |
| RPLP1 | ribosomal protein, large, P1 | -0.047478 |
| RPL23 | ribosomal protein L23 | -0.0444317 |
| PTMA | prothymosin, alpha | -0.0417775 |
| RPS24 | ribosomal protein S24 | -0.0408536 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.039511 |
| MED13 | mediator complex subunit 13 | -0.0380556 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0374871 |
| TMSB10 | thymosin beta 10 | -0.0343306 |
| GLCCI1 | glucocorticoid induced 1 | -0.0336912 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0331826 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0330477 |
| RPS6 | ribosomal protein S6 | -0.032172 |
| POTEF | POTE ankyrin domain family, member F | -0.0315771 |
| RPS11 | ribosomal protein S11 | -0.0304058 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0299399 |
| EGR1 | early growth response 1 | -0.0287938 |
| GLG1 | golgi glycoprotein 1 | -0.0287448 |
| RPS23 | ribosomal protein S23 | -0.0278559 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0274005 |
| RPS25 | ribosomal protein S25 | -0.0258362 |
| RPS19 | ribosomal protein S19 | -0.0258163 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0257693 |
| FTL | ferritin, light polypeptide | -0.0256148 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0252795 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0249405 |
| RPL28 | ribosomal protein L28 | -0.0247617 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.024738 |
| RPL36 | ribosomal protein L36 | -0.0243503 |
| RPL32 | ribosomal protein L32 | -0.0243446 |
| SIK2 | salt-inducible kinase 2 | -0.0241098 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0239837 |
| PHIP | pleckstrin homology domain interacting protein | -0.0239407 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0236183 |
| ZNF207 | zinc finger protein 207 | -0.0233612 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0231137 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | -0.0227047 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0225584 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0223889 |
| GNAS | GNAS complex locus | -0.0222476 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0222251 |
| S100A9 | S100 calcium binding protein A9 | -0.0220815 |
| RPL31 | ribosomal protein L31 | -0.0220506 |
| USP36 | ubiquitin specific peptidase 36 | -0.0220225 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | -0.0220002 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0217487 |
| GPATCH8 | G patch domain containing 8 | -0.0214477 |
| SRP54 | signal recognition particle 54kDa | -0.0214056 |
| USP3 | ubiquitin specific peptidase 3 | -0.0208625 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0207509 |
| FOXK2 | forkhead box K2 | -0.0206835 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0206732 |
| UBAP2 | ubiquitin associated protein 2 | -0.0203742 |
| RPS13 | ribosomal protein S13 | -0.0202928 |
| RPS21 | ribosomal protein S21 | -0.0201205 |
| RPS15 | ribosomal protein S15 | -0.020058 |
| TAOK1 | TAO kinase 1 | -0.0200532 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0199971 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0199425 |
| RPS29 | ribosomal protein S29 | -0.0198267 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.019807 |
| OLA1 | Obg-like ATPase 1 | -0.0197399 |
| NOP58 | NOP58 ribonucleoprotein | -0.0197154 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0195276 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0192977 |
| RPLP0 | ribosomal protein, large, P0 | -0.0192589 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0192178 |
| RPS10 | ribosomal protein S10 | -0.0191117 |
| CDK13 | cyclin-dependent kinase 13 | -0.0190894 |
| RPS16 | ribosomal protein S16 | -0.0190344 |
| GPC5 | glypican 5 | -0.0189283 |
| CLTC | clathrin, heavy chain (Hc) | -0.0188899 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0186883 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0186831 |
| LMNA | lamin A/C | -0.0186115 |
| TBCA | tubulin folding cofactor A | -0.0186083 |
| RPL7 | ribosomal protein L7 | -0.0181468 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0181079 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0177443 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0175218 |
| PLAT | plasminogen activator, tissue | -0.0174569 |
| ANKRD10 | ankyrin repeat domain 10 | -0.017301 |
| RBM25 | RNA binding motif protein 25 | -0.0172922 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0172455 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0171897 |
| INTS6 | integrator complex subunit 6 | -0.0170272 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0169995 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0168082 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0168054 |
| IER3 | immediate early response 3 | -0.0168039 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0167749 |
| GOLGA4 | golgin A4 | -0.0167237 |
