| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diphenhydramine perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diphenhydramine_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.108363 |
| MEF2A | myocyte enhancer factor 2A | 0.107145 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.104783 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.094737 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0941703 |
| ENO1 | enolase 1, (alpha) | 0.0931865 |
| MSN | moesin | 0.0828853 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0809394 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0677889 |
| ANXA1 | annexin A1 | 0.0662744 |
| CLU | clusterin | 0.0659623 |
| KRT17 | keratin 17, type I | 0.0657163 |
| TMSB4X | thymosin beta 4, X-linked | 0.0627972 |
| ITGA6 | integrin, alpha 6 | 0.0615856 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0604276 |
| ARRDC3 | arrestin domain containing 3 | 0.0572091 |
| RPS2 | ribosomal protein S2 | 0.0569468 |
| CANX | calnexin | 0.056638 |
| TPM3 | tropomyosin 3 | 0.055432 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0544907 |
| MTSS1 | metastasis suppressor 1 | 0.0542018 |
| GOLGA4 | golgin A4 | 0.053965 |
| PGK1 | phosphoglycerate kinase 1 | 0.0539415 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0530602 |
| EZR | ezrin | 0.052062 |
| MYOF | myoferlin | 0.0512316 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0506717 |
| KRT6A | keratin 6A, type II | 0.0499393 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0481365 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0474948 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.04714 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0466818 |
| PTMA | prothymosin, alpha | 0.045518 |
| ANLN | anillin, actin binding protein | 0.045324 |
| PCDH1 | protocadherin 1 | 0.0431111 |
| SLK | STE20-like kinase | 0.0407155 |
| PCBP2 | poly(rC) binding protein 2 | 0.0389651 |
| EMP1 | epithelial membrane protein 1 | 0.0386912 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0380804 |
| DSTN | destrin (actin depolymerizing factor) | 0.0378058 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0376005 |
| TMF1 | TATA element modulatory factor 1 | 0.037588 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0371585 |
| MYO10 | myosin X | 0.0359655 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.035537 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.035234 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0352257 |
| FLNA | filamin A, alpha | 0.0347559 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0344705 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0339728 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0337789 |
| SET | SET nuclear proto-oncogene | 0.0330384 |
| RAI14 | retinoic acid induced 14 | 0.0327678 |
| ADM | adrenomedullin | 0.0327262 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0327245 |
| OGA | O-GlcNAcase | 0.0321334 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0308525 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.030823 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0305254 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0301361 |
| CENPF | centromere protein F, 350/400kDa | 0.029946 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0294721 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0294254 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.029307 |
| TLN1 | talin 1 | 0.0277402 |
| RAI1 | retinoic acid induced 1 | 0.0277052 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0276421 |
| CEP250 | centrosomal protein 250kDa | 0.0275339 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0271767 |
| STC1 | stanniocalcin 1 | 0.0269431 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0269233 |
| KIAA1217 | KIAA1217 | 0.0268971 |
| YBX1 | Y box binding protein 1 | 0.026828 |
| ZNF292 | zinc finger protein 292 | 0.0268239 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0268071 |
| FNIP1 | folliculin interacting protein 1 | 0.0267582 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0266996 |
| RPL3 | ribosomal protein L3 | 0.0266268 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.026353 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0263323 |
| INSIG2 | insulin induced gene 2 | 0.0261976 |
| HDGF | hepatoma-derived growth factor | 0.0261854 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0261772 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0261738 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0259813 |
| CUL4B | cullin 4B | 0.0255166 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.025344 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0253174 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0251938 |
| FAM13A | family with sequence similarity 13, member A | 0.0249537 |
| ANGPTL4 | angiopoietin-like 4 | 0.0245172 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0244874 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0239961 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0239671 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0238126 |
| MKI67 | marker of proliferation Ki-67 | 0.0237097 |
| KIF16B | kinesin family member 16B | 0.0236233 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0235968 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0235664 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.0233267 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.252232 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.218403 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0703745 |
| PALLD | palladin, cytoskeletal associated protein | -0.0689705 |
| FOXO1 | forkhead box O1 | -0.0657781 |
| AOPEP | aminopeptidase O (putative) | -0.0629661 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0620497 |
| S100A10 | S100 calcium binding protein A10 | -0.0613108 |
| OSMR | oncostatin M receptor | -0.060836 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0589777 |
| HLA-B | major histocompatibility complex, class I, B | -0.0581223 |
| FOXP1 | forkhead box P1 | -0.0537283 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0534304 |
| TMSB10 | thymosin beta 10 | -0.0526502 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0523328 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0516653 |
| ACTN4 | actinin, alpha 4 | -0.0505666 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.049704 |
| SULF2 | sulfatase 2 | -0.0482464 |
| RPS21 | ribosomal protein S21 | -0.0477794 |
| INTS6 | integrator complex subunit 6 | -0.0466524 |
| LMO7 | LIM domain 7 | -0.0462239 |
| MT2A | metallothionein 2A | -0.0453009 |
| NEK7 | NIMA-related kinase 7 | -0.0442771 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0432707 |
| RIGI | RNA sensor RIG-I | -0.0432378 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0410689 |
| MECOM | MDS1 and EVI1 complex locus | -0.0401245 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0398596 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0393467 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0392717 |
| VCL | vinculin | -0.0389649 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0381055 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0370998 |
| GNAS | GNAS complex locus | -0.0369083 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0357484 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0356095 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0354338 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0350424 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.034962 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0344465 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0329928 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0324887 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0323445 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0322491 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0316047 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0315779 |
| RASAL2 | RAS protein activator like 2 | -0.031319 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0311154 |
| BCL2L1 | BCL2-like 1 | -0.0307676 |
| SMYD3 | SET and MYND domain containing 3 | -0.0307117 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0303108 |
| PITPNB | phosphatidylinositol transfer protein, beta | -0.0298324 |
| SMAD3 | SMAD family member 3 | -0.029644 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0294452 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0294126 |
| RPL34 | ribosomal protein L34 | -0.0291459 |
| SEPTIN9 | septin 9 | -0.0285428 |
| TXNRD1 | thioredoxin reductase 1 | -0.028475 |
| HM13 | histocompatibility (minor) 13 | -0.0284586 |
| FBXO11 | F-box protein 11 | -0.0283508 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.027731 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0276817 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0276673 |
| CLIC4 | chloride intracellular channel 4 | -0.0273399 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0273389 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0272519 |
| RPL8 | ribosomal protein L8 | -0.0270241 |
| RPS23 | ribosomal protein S23 | -0.0268919 |
| RPL32 | ribosomal protein L32 | -0.0263886 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0262637 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0262073 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0262048 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0258749 |
| EGR1 | early growth response 1 | -0.0257447 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0256398 |
| SETX | senataxin | -0.0255132 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0251946 |
| DGKH | diacylglycerol kinase, eta | -0.025192 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0250842 |
| RPS24 | ribosomal protein S24 | -0.0249867 |
| ASTN2 | astrotactin 2 | -0.0248993 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0247699 |
| EFNA5 | ephrin-A5 | -0.0247574 |
| BSG | basigin (Ok blood group) | -0.024461 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0243169 |
| IGF2 | insulin-like growth factor 2 | -0.0242562 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0242353 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0240947 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0237348 |
| IER3 | immediate early response 3 | -0.0236866 |
| EXOC6B | exocyst complex component 6B | -0.0234542 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0232141 |
| LDLR | low density lipoprotein receptor | -0.0231712 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0231534 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0230774 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0230184 |
| KIAA1671 | KIAA1671 | -0.0229273 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.022835 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0226969 |
