| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diphenhydramine perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diphenhydramine_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.145008 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.113933 |
| POTEF | POTE ankyrin domain family, member F | 0.102298 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0981171 |
| H1-0 | H1.0 linker histone | 0.0902235 |
| DSPP | dentin sialophosphoprotein | 0.0879184 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0877017 |
| MYOF | myoferlin | 0.0873505 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.081044 |
| ANLN | anillin, actin binding protein | 0.0784111 |
| EZR | ezrin | 0.0776204 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.076182 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0744838 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0728862 |
| PCBP2 | poly(rC) binding protein 2 | 0.0724563 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0720266 |
| HYOU1 | hypoxia up-regulated 1 | 0.0674858 |
| KRT8 | keratin 8, type II | 0.063384 |
| EMP1 | epithelial membrane protein 1 | 0.062372 |
| CALR | calreticulin | 0.0605547 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.060167 |
| CLDN4 | claudin 4 | 0.0567037 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.056325 |
| KRT18 | keratin 18, type I | 0.0529833 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0525278 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0509865 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0507976 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0487263 |
| FAT1 | FAT atypical cadherin 1 | 0.0478603 |
| TJP1 | tight junction protein 1 | 0.0475646 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0458993 |
| FLNB | filamin B, beta | 0.0457882 |
| ANXA11 | annexin A11 | 0.0451977 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0449425 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0440735 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0436778 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0427398 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0423612 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0422428 |
| ANXA2 | annexin A2 | 0.0422268 |
| ECT2 | epithelial cell transforming 2 | 0.0419869 |
| CAPN8 | calpain 8 | 0.041579 |
| STK24 | serine/threonine kinase 24 | 0.04078 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0402322 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0400019 |
| PLS1 | plastin 1 | 0.0395616 |
| KRT19 | keratin 19, type I | 0.0393744 |
| ITGA6 | integrin, alpha 6 | 0.0393403 |
| AHR | aryl hydrocarbon receptor | 0.0391903 |
| LIMA1 | LIM domain and actin binding 1 | 0.0389957 |
| TRIM2 | tripartite motif containing 2 | 0.0389704 |
| MKI67 | marker of proliferation Ki-67 | 0.0389185 |
| PLEC | plectin | 0.0385929 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.038282 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0381629 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0379974 |
| TMSB4X | thymosin beta 4, X-linked | 0.0378304 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0377847 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0373806 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0373499 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0368716 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0368599 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0361052 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0357476 |
| CCNL1 | cyclin L1 | 0.0346941 |
| SHROOM3 | shroom family member 3 | 0.0344307 |
| ACTN4 | actinin, alpha 4 | 0.0335257 |
| BRD2 | bromodomain containing 2 | 0.0333549 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0333473 |
| TMF1 | TATA element modulatory factor 1 | 0.0326192 |
| KRT17 | keratin 17, type I | 0.0324574 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0324564 |
| JUP | junction plakoglobin | 0.0324389 |
| PRELID2 | PRELI domain containing 2 | 0.0323919 |
| RBM39 | RNA binding motif protein 39 | 0.0323789 |
| LIPH | lipase, member H | 0.0320699 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0320376 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0317785 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.031422 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.031347 |
| XPO1 | exportin 1 | 0.031168 |
| LYZ | lysozyme | 0.0307736 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0305885 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.030467 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0299389 |
| TES | testin LIM domain protein | 0.0298885 |
| TRIM31 | tripartite motif containing 31 | 0.0293937 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0293038 |
| DSTN | destrin (actin depolymerizing factor) | 0.0292954 |
| SNX9 | sorting nexin 9 | 0.0292499 |
| FAM13A | family with sequence similarity 13, member A | 0.0290876 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0289613 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0288129 |
| SMAD3 | SMAD family member 3 | 0.0287092 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0286327 |
| CLIC1 | chloride intracellular channel 1 | 0.0286053 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0285222 |
| AREG | amphiregulin | 0.0284521 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0283558 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0282688 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.162565 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.140746 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.133652 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0861163 |
| CDK6 | cyclin-dependent kinase 6 | -0.0855952 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0745678 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0728883 |
| TMSB10 | thymosin beta 10 | -0.0680996 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0657999 |
| RPS6 | ribosomal protein S6 | -0.0638436 |
| TMEM123 | transmembrane protein 123 | -0.0608073 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0575031 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0563851 |
| TMC5 | transmembrane channel-like 5 | -0.055429 |
| FTL | ferritin, light polypeptide | -0.0517518 |
| ATF5 | activating transcription factor 5 | -0.0510393 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0502896 |
| PTMA | prothymosin, alpha | -0.0500439 |
| AGR2 | anterior gradient 2 | -0.0473264 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0467814 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0464281 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0453366 |
| LCN2 | lipocalin 2 | -0.0450921 |
| HLA-A | major histocompatibility complex, class I, A | -0.0448902 |
| HLA-B | major histocompatibility complex, class I, B | -0.0427869 |
| AOPEP | aminopeptidase O (putative) | -0.0418656 |
| WDR45B | WD repeat domain 45B | -0.041103 |
| RUNX1 | runt-related transcription factor 1 | -0.0401283 |
| EHBP1 | EH domain binding protein 1 | -0.0398416 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.039563 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0392503 |
| RPL34 | ribosomal protein L34 | -0.0384268 |
| RPS25 | ribosomal protein S25 | -0.0352202 |
| FUS | FUS RNA binding protein | -0.0347109 |
| RPL36A | ribosomal protein L36a | -0.0345665 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0345466 |
| RPL38 | ribosomal protein L38 | -0.0344962 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0341096 |
| HLA-C | major histocompatibility complex, class I, C | -0.0341032 |
| TRIM56 | tripartite motif containing 56 | -0.0338894 |
| CUX1 | cut-like homeobox 1 | -0.0338789 |
| RPL35A | ribosomal protein L35a | -0.0336406 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.0331435 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0320561 |
| TNIK | TRAF2 and NCK interacting kinase | -0.0315345 |
| AUTS2 | autism susceptibility candidate 2 | -0.0312125 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0309768 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0307058 |
| NFIA | nuclear factor I/A | -0.0304118 |
| CCND1 | cyclin D1 | -0.0302831 |
| HLA-E | major histocompatibility complex, class I, E | -0.0300304 |
| NDRG1 | N-myc downstream regulated 1 | -0.0295674 |
| SULF2 | sulfatase 2 | -0.0294316 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0293976 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0292794 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0289611 |
| TFRC | transferrin receptor | -0.028516 |
| PGK1 | phosphoglycerate kinase 1 | -0.0284221 |
| PLCB4 | phospholipase C, beta 4 | -0.028099 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0277758 |
| RPS16 | ribosomal protein S16 | -0.0273411 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0272856 |
| DENND1A | DENN/MADD domain containing 1A | -0.0272062 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0271439 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0269449 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0267654 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0264149 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0259053 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0259039 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0258509 |
| ZFHX3 | zinc finger homeobox 3 | -0.0254972 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0254286 |
| ITGB4 | integrin, beta 4 | -0.0251422 |
| IER3 | immediate early response 3 | -0.0246637 |
| CMIP | c-Maf inducing protein | -0.0240735 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0239788 |
| KLHL29 | kelch-like family member 29 | -0.0239591 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0232811 |
| GNAS | GNAS complex locus | -0.0232 |
| PCDH7 | protocadherin 7 | -0.0230393 |
| RPS24 | ribosomal protein S24 | -0.0230259 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0229703 |
| COBL | cordon-bleu WH2 repeat protein | -0.0229459 |
| RPS29 | ribosomal protein S29 | -0.0226315 |
| RPLP1 | ribosomal protein, large, P1 | -0.0225788 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0225295 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0224296 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0223942 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0222997 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0222228 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0221792 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0220882 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 | -0.0219773 |
| FMNL2 | formin-like 2 | -0.0218192 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0218163 |
| TMEM181 | transmembrane protein 181 | -0.0215905 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0214653 |
| GPATCH8 | G patch domain containing 8 | -0.021385 |
| RTN3 | reticulon 3 | -0.0213644 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0213234 |
