| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diphenhydramine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diphenhydramine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.218164 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.16983 |
| CD44 | CD44 molecule (Indian blood group) | 0.169489 |
| FNDC3B | fibronectin type III domain containing 3B | 0.152143 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.107335 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.099058 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0914234 |
| SMAD3 | SMAD family member 3 | 0.0906198 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0858141 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0850906 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0842416 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0776217 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0755693 |
| EFNA5 | ephrin-A5 | 0.0739056 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0737484 |
| RAD51B | RAD51 paralog B | 0.0708459 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0615473 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0578653 |
| NAV2 | neuron navigator 2 | 0.0572898 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0567773 |
| PCBP2 | poly(rC) binding protein 2 | 0.0559082 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0555706 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0546748 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0521977 |
| PRELID2 | PRELI domain containing 2 | 0.05129 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0495396 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0489596 |
| FAM13A | family with sequence similarity 13, member A | 0.0483068 |
| STK38L | serine/threonine kinase 38 like | 0.0479052 |
| HAS2 | hyaluronan synthase 2 | 0.045397 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0452562 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0441648 |
| ADD3 | adducin 3 (gamma) | 0.0439423 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0433677 |
| OSMR | oncostatin M receptor | 0.0432555 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0415435 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0405658 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0401868 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0401008 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0392614 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0390856 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.038738 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0383635 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0380937 |
| ASPH | aspartate beta-hydroxylase | 0.0378474 |
| SIK3 | SIK family kinase 3 | 0.0367756 |
| AHNAK | AHNAK nucleoprotein | 0.0359061 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0357396 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0356774 |
| FLNB | filamin B, beta | 0.0355779 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0353844 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0353054 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0349818 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0349184 |
| AHR | aryl hydrocarbon receptor | 0.0347454 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0342752 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.033276 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0327942 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0323923 |
| TGM2 | transglutaminase 2 | 0.0322429 |
| H1-0 | H1.0 linker histone | 0.0320311 |
| MYO10 | myosin X | 0.0314495 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0309072 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0308833 |
| CDCP1 | CUB domain containing protein 1 | 0.0308715 |
| ANGPTL4 | angiopoietin-like 4 | 0.0308531 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0304975 |
| MX1 | MX dynamin-like GTPase 1 | 0.0303762 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0303155 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0301688 |
| ATP13A3 | ATPase type 13A3 | 0.0301007 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.03009 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0298922 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0296123 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0293884 |
| RUNX1 | runt-related transcription factor 1 | 0.0290416 |
| GPC6 | glypican 6 | 0.0288564 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0286518 |
| ETV6 | ets variant 6 | 0.0282729 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.028148 |
| SLTM | SAFB-like, transcription modulator | 0.0281117 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0280482 |
| MSN | moesin | 0.0280405 |
| DST | dystonin | 0.0277865 |
| ZNF292 | zinc finger protein 292 | 0.0275401 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0275376 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0274121 |
| SFTPA2 | surfactant protein A2 | 0.0272682 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.027243 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0272148 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0270933 |
| RARB | retinoic acid receptor, beta | 0.0270776 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0270186 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0269567 |
| CEP250 | centrosomal protein 250kDa | 0.0269476 |
| TMSB4X | thymosin beta 4, X-linked | 0.0268611 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0267676 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0265315 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0263965 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.026301 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.146586 |
| TMSB10 | thymosin beta 10 | -0.122339 |
| VIM | vimentin | -0.11297 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0944644 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0748707 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0692493 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0653367 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0632043 |
| GOLGA4 | golgin A4 | -0.0629994 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0628779 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0567855 |
| LOX | lysyl oxidase | -0.056084 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0552125 |
| CDH13 | cadherin 13 | -0.0542805 |
| FTL | ferritin, light polypeptide | -0.0519641 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0509881 |
| DPYD | dihydropyrimidine dehydrogenase | -0.049316 |
| SYT1 | synaptotagmin I | -0.0482344 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0480777 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0474588 |
| STC1 | stanniocalcin 1 | -0.0434521 |
| PTMA | prothymosin, alpha | -0.0432301 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0411851 |
| IER3 | immediate early response 3 | -0.0408086 |
| USP34 | ubiquitin specific peptidase 34 | -0.0402142 |
| EGR1 | early growth response 1 | -0.0401099 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0400435 |
| RPL35A | ribosomal protein L35a | -0.0391623 |
| SRP54 | signal recognition particle 54kDa | -0.0387029 |
| HM13 | histocompatibility (minor) 13 | -0.038511 |
| DENND4A | DENN/MADD domain containing 4A | -0.0383548 |
| RAB7A | RAB7A, member RAS oncogene family | -0.037398 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0366429 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0365323 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0364422 |
| AADAC | arylacetamide deacetylase | -0.0361031 |
| ATF7 | activating transcription factor 7 | -0.0357214 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0356406 |
| COPA | coatomer protein complex, subunit alpha | -0.035498 |
| SEC24A | SEC24 family member A | -0.0354392 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0353226 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0349692 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0332863 |
| RPLP1 | ribosomal protein, large, P1 | -0.033109 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0327559 |
| FNIP1 | folliculin interacting protein 1 | -0.032608 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0322769 |
| TMEM263 | transmembrane protein 263 | -0.0321772 |
| FBN1 | fibrillin 1 | -0.0321423 |
| NDRG1 | N-myc downstream regulated 1 | -0.0320767 |
| RPS6 | ribosomal protein S6 | -0.0320052 |
| WASF2 | WAS protein family, member 2 | -0.0318401 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0317169 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0314266 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0312598 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0311024 |
| S100A6 | S100 calcium binding protein A6 | -0.0307718 |
| RPL34 | ribosomal protein L34 | -0.0304405 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0304153 |
| TMEM165 | transmembrane protein 165 | -0.0299571 |
| ARF4 | ADP-ribosylation factor 4 | -0.0299257 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0297354 |
| VRK2 | vaccinia related kinase 2 | -0.0294634 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.02941 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0292839 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0287418 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0286491 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0285816 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0284724 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0284093 |
| BPTF | bromodomain PHD finger transcription factor | -0.0283247 |
| RPL31 | ribosomal protein L31 | -0.0278506 |
| CDK13 | cyclin-dependent kinase 13 | -0.0272197 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0271884 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0270661 |
| RAB5A | RAB5A, member RAS oncogene family | -0.0270015 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0269563 |
| RPS29 | ribosomal protein S29 | -0.0269157 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0268592 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0267545 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0267097 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0264801 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0263995 |
| ZNF804A | zinc finger protein 804A | -0.0259037 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0257785 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0254724 |
| RPS24 | ribosomal protein S24 | -0.0254694 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0252956 |
| RPS19 | ribosomal protein S19 | -0.0250487 |
| NLK | nemo-like kinase | -0.0249649 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0248332 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0248268 |
| ZNF609 | zinc finger protein 609 | -0.0244981 |
| MORF4L2 | mortality factor 4 like 2 | -0.0239652 |
| DNER | delta/notch-like EGF repeat containing | -0.0238883 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0238719 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0238291 |
| HMGA1 | high mobility group AT-hook 1 | -0.0237528 |
| CUX1 | cut-like homeobox 1 | -0.0237233 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0236557 |
