| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diphenhydramine perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diphenhydramine_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.246799 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.243008 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.153241 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.150001 |
| PCBP2 | poly(rC) binding protein 2 | 0.119686 |
| TPM3 | tropomyosin 3 | 0.0852113 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0841052 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0809114 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0703059 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.069195 |
| CCNL1 | cyclin L1 | 0.064395 |
| TPI1 | triosephosphate isomerase 1 | 0.06365 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0594907 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0592132 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0550624 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0496348 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0490675 |
| SET | SET nuclear proto-oncogene | 0.0473652 |
| TLN1 | talin 1 | 0.0448933 |
| BRD2 | bromodomain containing 2 | 0.0447368 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0426455 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0421471 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0421082 |
| PNN | pinin, desmosome associated protein | 0.0413026 |
| RPS3 | ribosomal protein S3 | 0.0409799 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0407703 |
| RAD51B | RAD51 paralog B | 0.0400422 |
| RPL3 | ribosomal protein L3 | 0.0393 |
| YBX1 | Y box binding protein 1 | 0.0389729 |
| RPS2 | ribosomal protein S2 | 0.0382294 |
| POTEF | POTE ankyrin domain family, member F | 0.0382151 |
| HDGF | hepatoma-derived growth factor | 0.0378995 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0376143 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0361713 |
| MKI67 | marker of proliferation Ki-67 | 0.0355421 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.035049 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0347698 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.034079 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0338896 |
| WDR43 | WD repeat domain 43 | 0.0337089 |
| MSN | moesin | 0.0333159 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0330785 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0329433 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0320965 |
| ADAR | adenosine deaminase, RNA-specific | 0.031829 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0312863 |
| CEP192 | centrosomal protein 192kDa | 0.0309638 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0308317 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0305877 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0303857 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0296895 |
| CCDC200 | coiled-coil domain containing 200 | 0.0292576 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0292248 |
| ENO1 | enolase 1, (alpha) | 0.0284427 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0281248 |
| RPS12 | ribosomal protein S12 | 0.0278145 |
| SFTPA2 | surfactant protein A2 | 0.0276473 |
| SSRP1 | structure specific recognition protein 1 | 0.0271445 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 0.0269747 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0264399 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0258695 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0252661 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0252526 |
| COPA | coatomer protein complex, subunit alpha | 0.0249962 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0248597 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0247917 |
| RBM25 | RNA binding motif protein 25 | 0.024758 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0243529 |
| GOLGA4 | golgin A4 | 0.0241654 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0241567 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0241253 |
| NUP58 | nucleoporin 58 | 0.023754 |
| PTMS | parathymosin | 0.0235782 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0234421 |
| SPAG5 | sperm associated antigen 5 | 0.0229621 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0229496 |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.0227352 |
| KRT18 | keratin 18, type I | 0.0226204 |
| RPL37A | ribosomal protein L37a | 0.0224763 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0223394 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0218698 |
| FLNA | filamin A, alpha | 0.0218522 |
| ACTN1 | actinin, alpha 1 | 0.0216662 |
| FMNL2 | formin-like 2 | 0.0216548 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0214191 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0213895 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0211724 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0211549 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0210162 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0210149 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0210144 |
| RPS18 | ribosomal protein S18 | 0.0209717 |
| PRELID2 | PRELI domain containing 2 | 0.0207898 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0207563 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0206387 |
| DCAF8 | DDB1 and CUL4 associated factor 8 | 0.0205346 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0204673 |
| MSH6 | mutS homolog 6 | 0.0204553 |
| INTS13 | integrator complex subunit 13 | 0.0203543 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0203251 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.381107 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.145839 |
| TXNRD1 | thioredoxin reductase 1 | -0.0840707 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0697137 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0631306 |
| ACTG1 | actin gamma 1 | -0.0489633 |
| RPS21 | ribosomal protein S21 | -0.0474045 |
| OSMR | oncostatin M receptor | -0.0471782 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0470467 |
| GNAS | GNAS complex locus | -0.0464389 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0459339 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0453933 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0406386 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0400729 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0394398 |
| NF1 | neurofibromin 1 | -0.0392383 |
| RPLP0 | ribosomal protein, large, P0 | -0.0377981 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0364911 |
| YBX3 | Y box binding protein 3 | -0.0364706 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.036407 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0360422 |
| AHNAK | AHNAK nucleoprotein | -0.0350432 |
| RPL38 | ribosomal protein L38 | -0.0348436 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0347296 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0334399 |
| FBXO11 | F-box protein 11 | -0.0332843 |
| CCND2 | cyclin D2 | -0.033276 |
| RPS15 | ribosomal protein S15 | -0.0331099 |
| ATP11A | ATPase, class VI, type 11A | -0.0329097 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0324244 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0321467 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0319821 |
| RPL34 | ribosomal protein L34 | -0.0315007 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0314073 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0313724 |
| NABP1 | nucleic acid binding protein 1 | -0.0311888 |
| RPS24 | ribosomal protein S24 | -0.0310156 |
| FUS | FUS RNA binding protein | -0.0302181 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0301149 |
| TUBB | tubulin, beta class I | -0.029859 |
| TMSB10 | thymosin beta 10 | -0.0295344 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0294524 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0288842 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0288338 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0284112 |
| BSG | basigin (Ok blood group) | -0.0275923 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0271222 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0269328 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0265646 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0262914 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0259974 |
| ZNF217 | zinc finger protein 217 | -0.0255209 |
| CCND1 | cyclin D1 | -0.0254465 |
| ATF6 | activating transcription factor 6 | -0.0254225 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0252162 |
| TAOK1 | TAO kinase 1 | -0.0249633 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0249569 |
| RPS29 | ribosomal protein S29 | -0.0249484 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0248555 |
| CAVIN1 | caveolae associated protein 1 | -0.0247456 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0247351 |
| CDK13 | cyclin-dependent kinase 13 | -0.0243847 |
| PLSCR1 | phospholipid scramblase 1 | -0.0238043 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0236425 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.023394 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0233116 |
| RPL6 | ribosomal protein L6 | -0.023256 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0230269 |
| CDK12 | cyclin-dependent kinase 12 | -0.0229805 |
| DST | dystonin | -0.022974 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0229017 |
| TMEM263 | transmembrane protein 263 | -0.0228858 |
| IER3 | immediate early response 3 | -0.0225825 |
| ATG7 | autophagy related 7 | -0.0225182 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0225133 |
| HDLBP | high density lipoprotein binding protein | -0.022381 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0222109 |
| RPL8 | ribosomal protein L8 | -0.0222091 |
| GPHN | gephyrin | -0.0219635 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0219057 |
| RPLP1 | ribosomal protein, large, P1 | -0.0218486 |
| MYL12B | myosin, light chain 12B, regulatory | -0.021554 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0214922 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0213208 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0211389 |
| TRIM56 | tripartite motif containing 56 | -0.0211168 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0210825 |
| E2F3 | E2F transcription factor 3 | -0.0210142 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.020883 |
| TLK1 | tousled-like kinase 1 | -0.0206859 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0205374 |
| MAP4 | microtubule-associated protein 4 | -0.0202709 |
| RPL32 | ribosomal protein L32 | -0.0202312 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0201863 |
| GLO1 | glyoxalase I | -0.020069 |
| SMYD3 | SET and MYND domain containing 3 | -0.0200413 |
| ZFR | zinc finger RNA binding protein | -0.0198775 |
| PLEKHB2 | pleckstrin homology domain containing, family B (evectins) member 2 | -0.0198138 |
| ENOSF1 | enolase superfamily member 1 | -0.0198051 |
| ZXDC | ZXD family zinc finger C | -0.0197609 |
