| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diphenhydramine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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103 genes differentially expressed following the Diphenhydramine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.224404 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.171251 |
| LAMA4 | laminin, alpha 4 | 0.161093 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.15407 |
| USP34 | ubiquitin specific peptidase 34 | 0.126906 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.119389 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.118029 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.109671 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.107694 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.103802 |
| GRB10 | growth factor receptor-bound protein 10 | 0.103058 |
| PGK1 | phosphoglycerate kinase 1 | 0.0948853 |
| SFTPA2 | surfactant protein A2 | 0.0937783 |
| ZNF638 | zinc finger protein 638 | 0.090796 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0853284 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0834741 |
| SLTM | SAFB-like, transcription modulator | 0.0780194 |
| APP | amyloid beta (A4) precursor protein | 0.0755861 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0670008 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0666226 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0644822 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0629349 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0628144 |
| CLTC | clathrin, heavy chain (Hc) | 0.0614833 |
| LSAMP | limbic system-associated membrane protein | 0.0609614 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0598121 |
| EGFR | epidermal growth factor receptor | 0.0590648 |
| CTBP2 | C-terminal binding protein 2 | 0.0588939 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0567172 |
| MYO1E | myosin IE | 0.0559971 |
| MATR3 | matrin 3 | 0.0544429 |
| GPC6 | glypican 6 | 0.0543084 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0532239 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0524946 |
| RYBP | RING1 and YY1 binding protein | 0.0486608 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0477405 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.045235 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0424088 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0416905 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0397884 |
| RPS25 | ribosomal protein S25 | 0.0335652 |
| TNPO1 | transportin 1 | 0.0306889 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.027478 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.027069 |
| PDE10A | phosphodiesterase 10A | 0.0218796 |
| HDLBP | high density lipoprotein binding protein | 0.0197595 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0178122 |
| RPL23 | ribosomal protein L23 | 0.0177786 |
| PTK2 | protein tyrosine kinase 2 | 0.011988 |
| LDHA | lactate dehydrogenase A | 0.0117431 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.00750251 |
| PCBP3 | poly(rC) binding protein 3 | 0.00557036 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00524902 |
| PTMA | prothymosin, alpha | 0.00415104 |
| NAMPT | nicotinamide phosphoribosyltransferase | 3.79282E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.320144 |
| VIM | vimentin | -0.269883 |
| FN1 | fibronectin 1 | -0.229016 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.209263 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.191799 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.12202 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.111599 |
| VMP1 | vacuole membrane protein 1 | -0.101173 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0951181 |
| MT2A | metallothionein 2A | -0.0775863 |
| ASPH | aspartate beta-hydroxylase | -0.0681621 |
| NAV2 | neuron navigator 2 | -0.0671258 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0663435 |
| TMSB10 | thymosin beta 10 | -0.0616584 |
| CDH13 | cadherin 13 | -0.0615005 |
| RPS12 | ribosomal protein S12 | -0.0602326 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0596441 |
| NDRG1 | N-myc downstream regulated 1 | -0.0543717 |
| B2M | beta-2-microglobulin | -0.0522296 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0508897 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0500766 |
| IGF2 | insulin-like growth factor 2 | -0.0480373 |
| GOLGA4 | golgin A4 | -0.0473639 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0473449 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0470591 |
| VCL | vinculin | -0.0422623 |
| RPS8 | ribosomal protein S8 | -0.0419983 |
| MCL1 | myeloid cell leukemia 1 | -0.0389044 |
| STC1 | stanniocalcin 1 | -0.038325 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0374169 |
| RPS19 | ribosomal protein S19 | -0.0373559 |
| SMYD3 | SET and MYND domain containing 3 | -0.0344728 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0343253 |
| FLNB | filamin B, beta | -0.0327018 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0230913 |
| ZNF292 | zinc finger protein 292 | -0.0225573 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0219652 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0175605 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0150881 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0136757 |
| EFNA5 | ephrin-A5 | -0.0130604 |
| PARD3 | par-3 family cell polarity regulator | -0.0110613 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0108394 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.00936961 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.00899878 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.00459295 |
| MED13L | mediator complex subunit 13-like | -0.00152378 |
| HMGA2 | high mobility group AT-hook 2 | -1.9663E-4 |
