| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diphenhydramine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diphenhydramine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.155166 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.124732 |
| TMSB4X | thymosin beta 4, X-linked | 0.0919075 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0890034 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0732836 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0703447 |
| ZNF292 | zinc finger protein 292 | 0.0677583 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0589418 |
| DST | dystonin | 0.0588195 |
| MKI67 | marker of proliferation Ki-67 | 0.0575871 |
| PEG10 | paternally expressed 10 | 0.0556518 |
| GPC3 | glypican 3 | 0.0550817 |
| ANXA1 | annexin A1 | 0.0530532 |
| TPM3 | tropomyosin 3 | 0.0506599 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0494567 |
| ENAH | enabled homolog (Drosophila) | 0.0494081 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0478111 |
| CENPF | centromere protein F, 350/400kDa | 0.0476395 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0460499 |
| HMGB2 | high mobility group box 2 | 0.0458483 |
| COL5A2 | collagen, type V, alpha 2 | 0.0452564 |
| USP3 | ubiquitin specific peptidase 3 | 0.0446367 |
| RAI1 | retinoic acid induced 1 | 0.0432163 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0425279 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0419241 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0416538 |
| RPL7 | ribosomal protein L7 | 0.041292 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0412607 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0405476 |
| ENO1 | enolase 1, (alpha) | 0.0404616 |
| YBX1 | Y box binding protein 1 | 0.0402682 |
| VIM | vimentin | 0.0391581 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.038862 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.037764 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0376626 |
| MED13L | mediator complex subunit 13-like | 0.0376277 |
| SET | SET nuclear proto-oncogene | 0.0375532 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0360708 |
| MTF2 | metal response element binding transcription factor 2 | 0.0360032 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0352412 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0351976 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0351003 |
| H1-4 | H1.4 linker histone, cluster member | 0.0350752 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0349057 |
| RPS2 | ribosomal protein S2 | 0.0349056 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.034752 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.03456 |
| STAG2 | stromal antigen 2 | 0.0342967 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0342533 |
| TPX2 | TPX2, microtubule-associated | 0.0342333 |
| FLNA | filamin A, alpha | 0.0342109 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0341611 |
| RPL3 | ribosomal protein L3 | 0.0338004 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.033564 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0332672 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.032758 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0325801 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0322063 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0321415 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0320117 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0306625 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0303742 |
| KIF4A | kinesin family member 4A | 0.029672 |
| PGK1 | phosphoglycerate kinase 1 | 0.0296356 |
| CDC73 | cell division cycle 73 | 0.0295674 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | 0.0293944 |
| CALU | calumenin | 0.029257 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0290112 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0285161 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0284243 |
| CAVIN1 | caveolae associated protein 1 | 0.028359 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0282882 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0280453 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0279169 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0273749 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0271713 |
| PDS5B | PDS5 cohesin associated factor B | 0.0267823 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0267644 |
| CCN2 | cellular communication network factor 2 | 0.0265485 |
| POTEF | POTE ankyrin domain family, member F | 0.0265308 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0264201 |
| CCNL1 | cyclin L1 | 0.0263396 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0261941 |
| RPS7 | ribosomal protein S7 | 0.0257812 |
| H2AZ2 | H2A.Z variant histone 2 | 0.0257667 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0256611 |
| ATP5F1A | ATP synthase F1 subunit alpha | 0.0255643 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0255359 |
| CFL2 | cofilin 2 (muscle) | 0.0252875 |
| ECT2 | epithelial cell transforming 2 | 0.0249153 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.0246349 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0245208 |
| ANXA5 | annexin A5 | 0.0244859 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0240685 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0240523 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0240172 |
| RPL5 | ribosomal protein L5 | 0.0240141 |
| CANX | calnexin | 0.0239423 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0238608 |
| PDGFC | platelet derived growth factor C | 0.0236569 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.18238 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.163011 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.144578 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0985799 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0913845 |
| CADM2 | cell adhesion molecule 2 | -0.0830837 |
| RAD51B | RAD51 paralog B | -0.0614509 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0601882 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0598938 |
| AHNAK | AHNAK nucleoprotein | -0.0584775 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0536122 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0526356 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0525862 |
| JMJD1C | jumonji domain containing 1C | -0.0523613 |
| ITGAV | integrin, alpha V | -0.0497996 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0468631 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0458223 |
| SPAG9 | sperm associated antigen 9 | -0.045646 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0454704 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.045409 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0435099 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0431562 |
| SMYD3 | SET and MYND domain containing 3 | -0.0431032 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0430226 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0426814 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0402291 |
| USP34 | ubiquitin specific peptidase 34 | -0.0399097 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0397434 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.038981 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0389666 |
| LRRC4C | leucine rich repeat containing 4C | -0.0378915 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0378705 |
| PCDH9 | protocadherin 9 | -0.0376704 |
| BBX | bobby sox homolog (Drosophila) | -0.0375086 |
| NHSL1 | NHS-like 1 | -0.0367213 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0360895 |
| DENND1A | DENN/MADD domain containing 1A | -0.0357844 |
| TOX | thymocyte selection-associated high mobility group box | -0.0357366 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0341089 |
| COL3A1 | collagen, type III, alpha 1 | -0.0340192 |
| NXN | nucleoredoxin | -0.0339146 |
| NDRG1 | N-myc downstream regulated 1 | -0.0337154 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0332347 |
| NRG1 | neuregulin 1 | -0.033124 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0330429 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0329765 |
| RPL19 | ribosomal protein L19 | -0.0325471 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.031762 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0315986 |
| COG5 | component of oligomeric golgi complex 5 | -0.0313087 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0311917 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0310016 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0309637 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0305284 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0302793 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0302582 |
| RPS21 | ribosomal protein S21 | -0.0298946 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.029186 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0289358 |
| MORF4L2 | mortality factor 4 like 2 | -0.0287748 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0286453 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0285527 |
| GPHN | gephyrin | -0.0282254 |
| ZNF385D | zinc finger protein 385D | -0.0280562 |
| RTN4 | reticulon 4 | -0.0277805 |
| FNIP1 | folliculin interacting protein 1 | -0.0276537 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0276014 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0272991 |
| MED13 | mediator complex subunit 13 | -0.0270086 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0269532 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0268883 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0267549 |
| RSF1 | remodeling and spacing factor 1 | -0.0267111 |
| PARD3B | par-3 family cell polarity regulator beta | -0.026689 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0266495 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0265476 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0264877 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0264218 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0261852 |
| PRKD1 | protein kinase D1 | -0.0261174 |
| KIAA1958 | KIAA1958 | -0.0260084 |
| ANK2 | ankyrin 2, neuronal | -0.0258578 |
| NTM | neurotrimin | -0.0257871 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0257856 |
| CDK13 | cyclin-dependent kinase 13 | -0.0257518 |
| TCF12 | transcription factor 12 | -0.0256399 |
| SRPK2 | SRSF protein kinase 2 | -0.0253601 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0252525 |
| TMSB10 | thymosin beta 10 | -0.0252036 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0250546 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0248693 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0248001 |
| RPS16 | ribosomal protein S16 | -0.0247909 |
| FTL | ferritin, light polypeptide | -0.0246795 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0246398 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0244142 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0241579 |
| ZFP30 | ZFP30 zinc finger protein | -0.0240178 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0239205 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0238754 |
