| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Diphenhydramine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Diphenhydramine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.126413 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.123365 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0706233 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0661523 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0481555 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0476714 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0476482 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0430328 |
| OGA | O-GlcNAcase | 0.0379925 |
| ARRDC3 | arrestin domain containing 3 | 0.0364347 |
| RPS2 | ribosomal protein S2 | 0.0357695 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0350241 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0333359 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0329092 |
| ATP13A3 | ATPase type 13A3 | 0.0317993 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0311416 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0288264 |
| ANLN | anillin, actin binding protein | 0.0279044 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0272963 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0268256 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0257962 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0251773 |
| ADM | adrenomedullin | 0.0250775 |
| PCBP2 | poly(rC) binding protein 2 | 0.0248594 |
| NAV2 | neuron navigator 2 | 0.0246238 |
| MSN | moesin | 0.0244733 |
| SPAG9 | sperm associated antigen 9 | 0.0232819 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0219793 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0216976 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0214647 |
| FLNA | filamin A, alpha | 0.0208359 |
| CEP250 | centrosomal protein 250kDa | 0.0207655 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0203289 |
| AFDN | afadin, adherens junction formation factor | 0.0200656 |
| VEGFA | vascular endothelial growth factor A | 0.0193313 |
| SFTPA2 | surfactant protein A2 | 0.0193142 |
| CADM1 | cell adhesion molecule 1 | 0.0193002 |
| SERINC1 | serine incorporator 1 | 0.0185576 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0178734 |
| PDE10A | phosphodiesterase 10A | 0.0171234 |
| HELZ | helicase with zinc finger | 0.0167936 |
| YTHDC1 | YTH domain containing 1 | 0.0161423 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0159056 |
| YBX1 | Y box binding protein 1 | 0.0158856 |
| NUP153 | nucleoporin 153kDa | 0.0154097 |
| KIF4A | kinesin family member 4A | 0.0153653 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.015304 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.015252 |
| ZNF292 | zinc finger protein 292 | 0.0148539 |
| SET | SET nuclear proto-oncogene | 0.0147888 |
| TMSB4X | thymosin beta 4, X-linked | 0.0146131 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0145524 |
| GOLGA4 | golgin A4 | 0.0144151 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0140526 |
| RPS18 | ribosomal protein S18 | 0.0139209 |
| TPM3 | tropomyosin 3 | 0.0138035 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0136506 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0133206 |
| USP37 | ubiquitin specific peptidase 37 | 0.0128657 |
| TEX10 | testis expressed 10 | 0.0127604 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0127407 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0126908 |
| SLC25A26 | solute carrier family 25 (S-adenosylmethionine carrier), member 26 | 0.0123896 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0123089 |
| RPL3 | ribosomal protein L3 | 0.0122869 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0122507 |
| FN1 | fibronectin 1 | 0.0122328 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0121675 |
| MKI67 | marker of proliferation Ki-67 | 0.0121478 |
| CEP95 | centrosomal protein 95kDa | 0.0121428 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0121345 |
| DIAPH3 | diaphanous-related formin 3 | 0.011912 |
| APP | amyloid beta (A4) precursor protein | 0.0118871 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0118642 |
| NUP58 | nucleoporin 58 | 0.011712 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0116217 |
| KIF18A | kinesin family member 18A | 0.0115922 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0115277 |
| ECD | ecdysoneless homolog (Drosophila) | 0.0114979 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0113584 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0112336 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0112042 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0111493 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0111432 |
| RPS3A | ribosomal protein S3A | 0.0111219 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0110606 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0110553 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0108263 |
| SPAG5 | sperm associated antigen 5 | 0.0108176 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0107301 |
| POM121 | POM121 transmembrane nucleoporin | 0.0107175 |
| TPR | translocated promoter region, nuclear basket protein | 0.0106733 |
| KIF11 | kinesin family member 11 | 0.0106531 |
| ANKRD36B | ankyrin repeat domain 36B | 0.010615 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0105737 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0105721 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0104669 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0102592 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0102386 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0102044 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.341587 |
| VIM | vimentin | -0.259103 |
| HLA-B | major histocompatibility complex, class I, B | -0.166916 |
| FTL | ferritin, light polypeptide | -0.138211 |
| TMSB10 | thymosin beta 10 | -0.119698 |
| IER3 | immediate early response 3 | -0.0985115 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0940675 |
| MT2A | metallothionein 2A | -0.0848839 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0835373 |
| RPS6 | ribosomal protein S6 | -0.0804285 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0798066 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0676635 |
| NDRG1 | N-myc downstream regulated 1 | -0.0671901 |
| GLIS3 | GLIS family zinc finger 3 | -0.0646111 |
| RPS23 | ribosomal protein S23 | -0.0616873 |
| HMGA2 | high mobility group AT-hook 2 | -0.0570125 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0559025 |
| FRMD4A | FERM domain containing 4A | -0.0558952 |
| VCL | vinculin | -0.0548012 |
| ENO1 | enolase 1, (alpha) | -0.0534533 |
| ACTG1 | actin gamma 1 | -0.0529547 |
| RPLP1 | ribosomal protein, large, P1 | -0.0512287 |
| RPL35A | ribosomal protein L35a | -0.0507739 |
| HLA-A | major histocompatibility complex, class I, A | -0.0507167 |
| LDHA | lactate dehydrogenase A | -0.0494552 |
| CD44 | CD44 molecule (Indian blood group) | -0.0491824 |
| RPS19 | ribosomal protein S19 | -0.0488023 |
| RPL23 | ribosomal protein L23 | -0.0479675 |
| RPLP2 | ribosomal protein, large, P2 | -0.0478898 |
| B2M | beta-2-microglobulin | -0.0475863 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0462231 |
| BICC1 | BicC family RNA binding protein 1 | -0.0454485 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0443938 |
| CTSD | cathepsin D | -0.0440807 |
| RPL19 | ribosomal protein L19 | -0.0433507 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0430291 |
| RPS24 | ribosomal protein S24 | -0.0429396 |
| ASPH | aspartate beta-hydroxylase | -0.0421157 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0418548 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0416568 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0414941 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0412558 |
| DIAPH2 | diaphanous-related formin 2 | -0.0408504 |
| RPS13 | ribosomal protein S13 | -0.040778 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0407222 |
| EGR1 | early growth response 1 | -0.0406625 |
| RPS8 | ribosomal protein S8 | -0.040095 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0400234 |
| RPL36A | ribosomal protein L36a | -0.0396765 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0389157 |
| ATXN1 | ataxin 1 | -0.0376362 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0370521 |
| RPS21 | ribosomal protein S21 | -0.0367156 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0363495 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0360708 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0359932 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0358268 |
| RPL7A | ribosomal protein L7a | -0.0355782 |
| GPC6 | glypican 6 | -0.0348815 |
| SQSTM1 | sequestosome 1 | -0.0347309 |
| RPL32 | ribosomal protein L32 | -0.0346293 |
| BPTF | bromodomain PHD finger transcription factor | -0.0342903 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0340791 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0336473 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0335334 |
| PKM | pyruvate kinase, muscle | -0.0332507 |
| ASTN2 | astrotactin 2 | -0.0324685 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0324569 |
| RPL12 | ribosomal protein L12 | -0.0319076 |
| RPL31 | ribosomal protein L31 | -0.0317814 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0315517 |
| RPS25 | ribosomal protein S25 | -0.0314131 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0313936 |
| S100A9 | S100 calcium binding protein A9 | -0.0313444 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0313085 |
| RPL36 | ribosomal protein L36 | -0.0312265 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0311949 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0311844 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0310434 |
| NAV1 | neuron navigator 1 | -0.0309976 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0307993 |
| TNS3 | tensin 3 | -0.0303717 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0302028 |
| RNF213 | ring finger protein 213 | -0.0300542 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0300482 |
| RPS10 | ribosomal protein S10 | -0.0300019 |
| HDAC9 | histone deacetylase 9 | -0.0299625 |
| TAPBP | TAP binding protein (tapasin) | -0.0297636 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0295981 |
| CDH13 | cadherin 13 | -0.0294278 |
| RPL34 | ribosomal protein L34 | -0.0293585 |
| GNAS | GNAS complex locus | -0.0293316 |
| RPL28 | ribosomal protein L28 | -0.0293271 |
| RPLP0 | ribosomal protein, large, P0 | -0.0292683 |
| UBC | ubiquitin C | -0.0292313 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0292309 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0283309 |
| RPL9 | ribosomal protein L9 | -0.0282706 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0278409 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0278242 |
