Diplopia Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Diplopia is a condition in which a single object is perceived as two images, it is also known as double vision. (Human Phenotype Ontology, HP_0000651)
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D004172
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Genes

91 genes/proteins associated with the disease Diplopia from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.21798
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 2.17396
IL6 interleukin 6 2.12159
TNF tumor necrosis factor 2.0232
IL1B interleukin 1, beta 1.8978
IFNG interferon, gamma 1.87609
BCL2 B-cell CLL/lymphoma 2 1.85852
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.84746
FAS Fas cell surface death receptor 1.80623
CAT catalase 1.78759
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 1.74984
NOS2 nitric oxide synthase 2, inducible 1.70761
BAX BCL2-associated X protein 1.70719
CXCL8 chemokine (C-X-C motif) ligand 8 1.70203
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.68506
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 1.57402
TP53 tumor protein p53 1.56994
CCL2 chemokine (C-C motif) ligand 2 1.54839
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 1.54014
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 1.52515
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 1.52161
FOS FBJ murine osteosarcoma viral oncogene homolog 1.47012
CTSL cathepsin L 1.4591
BCL2L1 BCL2-like 1 1.45194
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.44817
S100A9 S100 calcium binding protein A9 1.44653
JUN jun proto-oncogene 1.44599
IL10 interleukin 10 1.44273
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 1.41559
HMOX1 heme oxygenase 1 1.39952
MCL1 myeloid cell leukemia 1 1.39702
MAPK3 mitogen-activated protein kinase 3 1.3682
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.36735
MAPK1 mitogen-activated protein kinase 1 1.35792
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.35299
SOD2 superoxide dismutase 2, mitochondrial 1.34053
REN renin 1.33316
ICAM1 intercellular adhesion molecule 1 1.33316
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 1.32518
CALCA calcitonin-related polypeptide alpha 1.31416
ALB albumin 1.30056
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.29719
IL4 interleukin 4 1.29688
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.29194
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 1.27378
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.26545
CNR1 cannabinoid receptor 1 (brain) 1.25369
CCND1 cyclin D1 1.2456
PRL prolactin 1.23456
EGR1 early growth response 1 1.23169
DDIT3 DNA-damage-inducible transcript 3 1.20196
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.19868
POMC proopiomelanocortin 1.19704
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 1.19607
IL23A interleukin 23, alpha subunit p19 1.18026
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.16967
TLR4 toll-like receptor 4 1.16137
S100A8 S100 calcium binding protein A8 1.15763
CLU clusterin 1.15593
VEGFA vascular endothelial growth factor A 1.1461
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 1.14438
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.14064
PARP1 poly (ADP-ribose) polymerase 1 1.13007
NR1I2 nuclear receptor subfamily 1, group I, member 2 1.12082
CCL3 chemokine (C-C motif) ligand 3 1.10977
IL2 interleukin 2 1.10493
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 1.09506
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.09119
MMP3 matrix metallopeptidase 3 1.08797
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.08442
BDNF brain-derived neurotrophic factor 1.08126
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 1.08019
NEFH neurofilament, heavy polypeptide 1.07128
PDE4B phosphodiesterase 4B, cAMP-specific 1.07128
CCL5 chemokine (C-C motif) ligand 5 1.07057
NOS3 nitric oxide synthase 3 (endothelial cell) 1.06952
HLA-B major histocompatibility complex, class I, B 1.06881
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 1.05386
MAPK8 mitogen-activated protein kinase 8 1.05163
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 1.04501
TAGLN transgelin 1.04276
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.03901
SLC22A6 solute carrier family 22 (organic anion transporter), member 6 1.03678
BMP4 bone morphogenetic protein 4 1.03641
HSPA8 heat shock 70kDa protein 8 1.03604
GADD45A growth arrest and DNA-damage-inducible, alpha 1.03456
AVP arginine vasopressin 1.03271
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.03122
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.02783
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 1.02559
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.01399