Diseases associated with the TLR signaling cascade Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-5602358
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Genes

32 proteins participating in the Diseases associated with the TLR signaling cascade pathway from the Reactome Pathways 2024 dataset.

Symbol Name
BTK Bruton agammaglobulinemia tyrosine kinase
CD14 CD14 molecule
CD36 CD36 molecule (thrombospondin receptor)
CHUK conserved helix-loop-helix ubiquitous kinase
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
HMGB1 high mobility group box 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IRAK4 interleukin-1 receptor-associated kinase 4
LY96 lymphocyte antigen 96
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
S100A1 S100 calcium binding protein A1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
TICAM1 toll-like receptor adaptor molecule 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TRAF3 TNF receptor-associated factor 3
UNC93B1 unc-93 homolog B1 (C. elegans)