Diseases of glycosylation Gene Set

Dataset Reactome Pathways 2014
Category structural or functional annotations
Type pathway
External Link http://www.reactome.org/PathwayBrowser/#/R-HSA-3781865
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Genes

227 proteins participating in the Diseases of glycosylation pathway from the Reactome Pathways dataset.

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACAN aggrecan
AGRN agrin
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
ALG10 ALG10, alpha-1,2-glucosyltransferase
ALG10B ALG10B, alpha-1,2-glucosyltransferase
ALG11 ALG11, alpha-1,2-mannosyltransferase
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALG3 ALG3, alpha-1,3- mannosyltransferase
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ALG6 ALG6, alpha-1,3-glucosyltransferase
ALG8 ALG8, alpha-1,3-glucosyltransferase
ALG9 ALG9, alpha-1,2-mannosyltransferase
ARSB arylsulfatase B
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
B3GAT1 beta-1,3-glucuronyltransferase 1
B3GAT2 beta-1,3-glucuronyltransferase 2
B3GAT3 beta-1,3-glucuronyltransferase 3
B3GNT1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B3GNT7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BCAN brevican
BGN biglycan
CALR calreticulin
CANX calnexin
CD44 CD44 molecule (Indian blood group)
CHP1 calcineurin-like EF-hand protein 1
CHPF chondroitin polymerizing factor
CHPF2 chondroitin polymerizing factor 2
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST13 carbohydrate (chondroitin 4) sulfotransferase 13
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CHST9 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
CHSY1 chondroitin sulfate synthase 1
CHSY3 chondroitin sulfate synthase 3
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CSPG4 chondroitin sulfate proteoglycan 4
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CTSA cathepsin A
DAD1 defender against cell death 1
DCN decorin
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic)
DHDDS dehydrodolichyl diphosphate synthase
DOLK dolichol kinase
DOLPP1 dolichyldiphosphatase 1
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
DSE dermatan sulfate epimerase
DSEL dermatan sulfate epimerase-like
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EDEM3 ER degradation enhancer, mannosidase alpha-like 3
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
FMOD fibromodulin
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GANAB glucosidase, alpha; neutral AB
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLB1 galactosidase, beta 1
GLB1L galactosidase, beta 1-like
GLCE glucuronic acid epimerase
GMPPA GDP-mannose pyrophosphorylase A
GMPPB GDP-mannose pyrophosphorylase B
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1
GNS glucosamine (N-acetyl)-6-sulfatase
GPC1 glypican 1
GPC2 glypican 2
GPC3 glypican 3
GPC4 glypican 4
GPC5 glypican 5
GPC6 glypican 6
GUSB glucuronidase, beta
GXYLT1 glucoside xylosyltransferase 1
GXYLT2 glucoside xylosyltransferase 2
HAS1 hyaluronan synthase 1
HAS2 hyaluronan synthase 2
HAS3 hyaluronan synthase 3
HEXA hexosaminidase A (alpha polypeptide)
HEXB hexosaminidase B (beta polypeptide)
HMMR hyaluronan-mediated motility receptor (RHAMM)
HPSE heparanase
HPSE2 heparanase 2 (inactive)
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4
HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
HS3ST6 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HS6ST2 heparan sulfate 6-O-sulfotransferase 2
HS6ST3 heparan sulfate 6-O-sulfotransferase 3
HSPG2 heparan sulfate proteoglycan 2
HYAL1 hyaluronoglucosaminidase 1
HYAL2 hyaluronoglucosaminidase 2
HYAL3 hyaluronoglucosaminidase 3
IDS iduronate 2-sulfatase
IDUA iduronidase, alpha-L-
KERA keratocan
LMAN1 lectin, mannose-binding, 1
LUM lumican
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAGT1 magnesium transporter 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN1A2 mannosidase, alpha, class 1A, member 2
MAN1B1 mannosidase, alpha, class 1B, member 1
MAN1C1 mannosidase, alpha, class 1C, member 1
MAN2A1 mannosidase, alpha, class 2A, member 1
MAN2A2 mannosidase, alpha, class 2A, member 2
MANEA mannosidase, endo-alpha
MCFD2 multiple coagulation factor deficiency 2
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
MGAT4C MGAT4 family, member C
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MLEC malectin
MOGS mannosyl-oligosaccharide glucosidase
MPDU1 mannose-P-dolichol utilization defect 1
MPI mannose phosphate isomerase
MVD mevalonate (diphospho) decarboxylase
NAGLU N-acetylglucosaminidase, alpha
NANP N-acetylneuraminic acid phosphatase
NANS N-acetylneuraminic acid synthase
NCAN neurocan
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
NEU1 sialidase 1 (lysosomal sialidase)
NEU2 sialidase 2 (cytosolic sialidase)
NEU3 sialidase 3 (membrane sialidase)
NEU4 sialidase 4
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OGN osteoglycin
OMD osteomodulin
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDIA3 protein disulfide isomerase family A, member 3
PGM3 phosphoglucomutase 3
PMM1 phosphomannomutase 1
PMM2 phosphomannomutase 2
PREB prolactin regulatory element binding
PRELP proline/arginine-rich end leucine-rich repeat protein
PRKCSH protein kinase C substrate 80K-H
RFT1 RFT1 homolog (S. cerevisiae)
RPN1 ribophorin I
RPN2 ribophorin II
SAR1B secretion associated, Ras related GTPase 1B
SDC1 syndecan 1
SDC2 syndecan 2
SDC3 syndecan 3
SDC4 syndecan 4
SEC13 SEC13 homolog (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24A SEC24 family member A
SEC24B SEC24 family member B
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SEC31A SEC31 homolog A (S. cerevisiae)
SGSH N-sulfoglucosamine sulfohydrolase
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STAB2 stabilin 2
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
TUSC3 tumor suppressor candidate 3
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UST uronyl-2-sulfotransferase
VCAN versican