Diseases of glycosylation Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-3781865
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Genes

145 proteins participating in the Diseases of glycosylation pathway from the Reactome Pathways 2024 dataset.

Symbol Name
ACAN aggrecan
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16
ADAMTS17 ADAM metallopeptidase with thrombospondin type 1 motif, 17
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9
ADAMTSL1 ADAMTS-like 1
ADAMTSL2 ADAMTS-like 2
ADAMTSL3 ADAMTS-like 3
ADAMTSL4 ADAMTS-like 4
ADAMTSL5 ADAMTS-like 5
AGRN agrin
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
ALG11 ALG11, alpha-1,2-mannosyltransferase
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALG3 ALG3, alpha-1,3- mannosyltransferase
ALG6 ALG6, alpha-1,3-glucosyltransferase
ALG8 ALG8, alpha-1,3-glucosyltransferase
ALG9 ALG9, alpha-1,2-mannosyltransferase
B3GALT6 UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
B3GAT3 beta-1,3-glucuronyltransferase 3
B3GLCT beta 3-glucosyltransferase
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
B4GAT1 beta-1,4-glucuronyltransferase 1
BCAN brevican
BGN biglycan
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1GALT1C1 C1GALT1-specific chaperone 1
CFP complement factor properdin
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CHSY1 chondroitin sulfate synthase 1
CSPG4 chondroitin sulfate proteoglycan 4
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CTSA cathepsin A
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DCN decorin
DHDDS dehydrodolichyl diphosphate synthase
DOLK dolichol kinase
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
FMOD fibromodulin
GALE UDP-galactose-4-epimerase
GALK1 galactokinase 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GALT galactose-1-phosphate uridylyltransferase
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLB1 galactosidase, beta 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPC1 glypican 1
GPC2 glypican 2
GPC3 glypican 3
GPC4 glypican 4
GPC5 glypican 5
GPC6 glypican 6
HEXA hexosaminidase A (alpha polypeptide)
HEXB hexosaminidase B (beta polypeptide)
HSPG2 heparan sulfate proteoglycan 2
KERA keratocan
LARGE1 LARGE xylosyl- and glucuronyltransferase 1
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LUM lumican
MAN1B1 mannosidase, alpha, class 1B, member 1
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MOGS mannosyl-oligosaccharide glucosidase
MPDU1 mannose-P-dolichol utilization defect 1
MPI mannose phosphate isomerase
MUC1 mucin 1, cell surface associated
MUC12 mucin 12, cell surface associated
MUC13 mucin 13, cell surface associated
MUC15 mucin 15, cell surface associated
MUC16 mucin 16, cell surface associated
MUC17 mucin 17, cell surface associated
MUC19 mucin 19, oligomeric
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC20 mucin 20, cell surface associated
MUC21 mucin 21, cell surface associated
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MUC7 mucin 7, secreted
MUCL1 mucin-like 1
NCAN neurocan
NEU1 sialidase 1 (lysosomal sialidase)
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOTCH4 notch 4
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
OGN osteoglycin
OMD osteomodulin
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PGM1 phosphoglucomutase 1
PMM2 phosphomannomutase 2
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
POMT1 protein-O-mannosyltransferase 1
POMT2 protein-O-mannosyltransferase 2
PRELP proline/arginine-rich end leucine-rich repeat protein
RFT1 RFT1 homolog (S. cerevisiae)
SBSPON somatomedin B and thrombospondin, type 1 domain containing
SDC1 syndecan 1
SDC2 syndecan 2
SDC3 syndecan 3
SDC4 syndecan 4
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPON1 spondin 1, extracellular matrix protein
SPON2 spondin 2, extracellular matrix protein
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THSD1 thrombospondin, type I, domain containing 1
THSD4 thrombospondin, type I, domain containing 4
THSD7A thrombospondin, type I, domain containing 7A
THSD7B thrombospondin, type I, domain containing 7B
VCAN versican