Diseases of programmed cell death Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-9645723
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Genes

75 proteins participating in the Diseases of programmed cell death pathway from the Reactome Pathways 2024 dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C1QBP complement component 1, q subcomponent binding protein
CAPN1 calpain 1, (mu/I) large subunit
CAPN2 calpain 2, (m/II) large subunit
CAPNS1 calpain, small subunit 1
CAPNS2 calpain, small subunit 2
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAST calpastatin
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN2A cyclin-dependent kinase inhibitor 2A
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EED embryonic ectoderm development
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FADD Fas (TNFRSF6)-associated via death domain
FASLG Fas ligand (TNF superfamily, member 6)
FOXO3 forkhead box O3
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOLGA2 golgin A2
GSDME gasdermin E
H2AB1 H2A.B variant histone 1
H2AC14 H2A clustered histone 14
H2AC18 H2A clustered histone 18
H2AC20 H2A clustered histone 20
H2AC4 H2A clustered histone 4
H2AC6 H2A clustered histone 6
H2AC7 H2A clustered histone 7
H2AJ H2A.J histone
H2AX H2A.X variant histone
H2AZ2 H2A.Z variant histone 2
H2BC1 H2B clustered histone 1
H2BC11 H2B clustered histone 11
H2BC12 H2B clustered histone 12
H2BC12L H2B clustered histone 12 like
H2BC13 H2B clustered histone 13
H2BC14 H2B clustered histone 14
H2BC15 H2B clustered histone 15
H2BC17 H2B clustered histone 17
H2BC21 H2B clustered histone 21
H2BC26 H2B clustered histone 26
H2BC3 H2B clustered histone 3
H2BC4 H2B clustered histone 4
H2BC5 H2B clustered histone 5
H2BC9 H2B clustered histone 9
H3-3A H3.3 histone A
H3C15 H3 clustered histone 15
H3C8 H3 clustered histone 8
H4C1 H4 clustered histone 1
JUN jun proto-oncogene
LMNA lamin A/C
LMNB1 lamin B1
MLKL mixed lineage kinase domain-like
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PRDX1 peroxiredoxin 1
PRDX2 peroxiredoxin 2
PRIM1 primase, DNA, polypeptide 1 (49kDa)
PRIM2 primase, DNA, polypeptide 2 (58kDa)
RBBP4 retinoblastoma binding protein 4
RBBP7 retinoblastoma binding protein 7
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RRM1 ribonucleotide reductase M1
SOD2 superoxide dismutase 2, mitochondrial
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TP53 tumor protein p53
TRADD TNFRSF1A-associated via death domain
TRAF2 TNF receptor-associated factor 2
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon