Dissection Of Aorta Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0340643
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Genes

133 genes associated with the disease Dissection Of Aorta in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ACSS2 acyl-CoA synthetase short-chain family member 2
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1C4 aldo-keto reductase family 1, member C4
ANGPT2 angiopoietin 2
ANGPTL6 angiopoietin-like 6
APOB apolipoprotein B
APOE apolipoprotein E
ATG4B autophagy related 4B, cysteine peptidase
ATG5 autophagy related 5
ATG7 autophagy related 7
BOP1 block of proliferation 1
CALR calreticulin
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCHCR1 coiled-coil alpha-helical rod protein 1
CCL2 chemokine (C-C motif) ligand 2
CCN2 cellular communication network factor 2
CCR2 chemokine (C-C motif) receptor 2
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COX1
COX2
COX3
CRISP2 cysteine-rich secretory protein 2
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
DBP D site of albumin promoter (albumin D-box) binding protein
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELN elastin
ENG endoglin
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FBLN1 fibulin 1
FBLN5 fibulin 5
FBN1 fibrillin 1
FHL1 four and a half LIM domains 1
FOXE3 forkhead box E3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCLC glutamate-cysteine ligase, catalytic subunit
GIF gastric intrinsic factor (vitamin B synthesis)
HDAC6 histone deacetylase 6
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IFNG interferon, gamma
IL11 interleukin 11
IL17A interleukin 17A
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL1B interleukin 1, beta
IL22 interleukin 22
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
KLF15 Kruppel-like factor 15
LATS1 large tumor suppressor kinase 1
LDLR low density lipoprotein receptor
LOX lysyl oxidase
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK3 mitogen-activated protein kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFN2 mitofusin 2
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MST1 macrophage stimulating 1
MSTN myostatin
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MT-ND5 NADH dehydrogenase, subunit 5 (complex I)
MT-ND6 NADH dehydrogenase, subunit 6 (complex I)
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
ND1
NFE2L2 nuclear factor, erythroid 2-like 2
NLRP3 NLR family, pyrin domain containing 3
PCSK9 proprotein convertase subtilisin/kexin type 9
PECAM1 platelet/endothelial cell adhesion molecule 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA2G15 phospholipase A2, group XV
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PRKG1 protein kinase, cGMP-dependent, type I
PRSS55 protease, serine, 55
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGFR prostaglandin F receptor (FP)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB7A RAB7A, member RAS oncogene family
RAB7B RAB7B, member RAS oncogene family
RAG1 recombination activating gene 1
RNF213 ring finger protein 213
RRAD Ras-related associated with diabetes
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SELE selectin E
SELENBP1 selenium binding protein 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SESN2 sestrin 2
SH2B3 SH2B adaptor protein 3
SHBG sex hormone-binding globulin
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SPINK5 serine peptidase inhibitor, Kazal type 5
SPP1 secreted phosphoprotein 1
SPZ1 spermatogenic leucine zipper 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK4 serine/threonine kinase 4
TAGLN transgelin
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
THBS1 thrombospondin 1
THBS4 thrombospondin 4
TIMP3 TIMP metallopeptidase inhibitor 3
TLN1 talin 1
TNF tumor necrosis factor
TNNI3 troponin I type 3 (cardiac)
TRIM25 tripartite motif containing 25
TRO trophinin
VKORC1 vitamin K epoxide reductase complex, subunit 1
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
YAP1 Yes-associated protein 1