Disulfiram Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description An organic disulfide that is 1,1'-[disulfanediylbis(carbonothioylimino)]diethane substituted by ethyl groups at the N atom. An EC 1.2.1.3 [aldehyde dehydrogenase (NAD+)] inhibitor, it is used as an alcohol deterrent. (Chemical Entities of Biological Interest Ontology, CHEBI_4659)
External Link http://ctdbase.org/detail.go?type=chem&acc=D004221
Similar Terms
Downloads & Tools

Genes

46 genes/proteins interacting with the chemical Disulfiram from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACHE acetylcholinesterase (Yt blood group)
AGXT2 alanine--glyoxylate aminotransferase 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AR androgen receptor
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
BAX BCL2-associated X protein
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCK cholecystokinin
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COX1
CREB1 cAMP responsive element binding protein 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCXR dicarbonyl/L-xylulose reductase
FSHB follicle stimulating hormone, beta polypeptide
GH1 growth hormone 1
HBG2 hemoglobin, gamma G
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
LHB luteinizing hormone beta polypeptide
MAPK8 mitogen-activated protein kinase 8
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NQO1 NAD(P)H dehydrogenase, quinone 1
PAM peptidylglycine alpha-amidating monooxygenase
PARP1 poly (ADP-ribose) polymerase 1
POMC proopiomelanocortin
PTEN phosphatase and tensin homolog
SOD1 superoxide dismutase 1, soluble
TAT tyrosine aminotransferase
TNF tumor necrosis factor
TRH thyrotropin-releasing hormone
TSHB thyroid stimulating hormone, beta