Dobutamine Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A catecholamine that is 4-(3-aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure. (Chemical Entities of Biological Interest Ontology, CHEBI_4670)
External Link http://ctdbase.org/detail.go?type=chem&acc=D004280
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Genes

67 genes/proteins interacting with the chemical Dobutamine from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ADCY6 adenylate cyclase 6
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AHSG alpha-2-HS-glycoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CLU clusterin
COMT catechol-O-methyltransferase
CPT1A carnitine palmitoyltransferase 1A (liver)
CREM cAMP responsive element modulator
CTF1 cardiotrophin 1
CXCL8 chemokine (C-X-C motif) ligand 8
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DMD dystrophin
EGFR epidermal growth factor receptor
ESR1 estrogen receptor 1
F3 coagulation factor III (thromboplastin, tissue factor)
FGF2 fibroblast growth factor 2 (basic)
FOS FBJ murine osteosarcoma viral oncogene homolog
G6PD glucose-6-phosphate dehydrogenase
GH1 growth hormone 1
GK glycerol kinase
GNAS GNAS complex locus
GSK3B glycogen synthase kinase 3 beta
HBEGF heparin-binding EGF-like growth factor
HMOX1 heme oxygenase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL6 interleukin 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUN jun proto-oncogene
JUND jun D proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KLK1 kallikrein 1
LEP leptin
LEPR leptin receptor
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK9 mitogen-activated protein kinase 9
MB myoglobin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
PLN phospholamban
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCE protein kinase C, epsilon
PROP1 PROP paired-like homeobox 1
REN renin
S100A1 S100 calcium binding protein A1
SPTAN1 spectrin, alpha, non-erythrocytic 1
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TNF tumor necrosis factor
USF1 upstream transcription factor 1
VEGFA vascular endothelial growth factor A