| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.215754 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.156367 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0720961 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0715017 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0612546 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0610867 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0574617 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0571201 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0566261 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0538183 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0528339 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0527498 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.046732 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0462822 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0447236 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0422246 |
| RPLP2 | ribosomal protein, large, P2 | 0.0412373 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0400735 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0391789 |
| LMO7 | LIM domain 7 | 0.0385312 |
| PDGFC | platelet derived growth factor C | 0.0384544 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0381983 |
| CCNL1 | cyclin L1 | 0.0364881 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0349875 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0348625 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0345412 |
| CBX3 | chromobox homolog 3 | 0.0333593 |
| DST | dystonin | 0.0332688 |
| KIF5B | kinesin family member 5B | 0.0332535 |
| NEK7 | NIMA-related kinase 7 | 0.0328767 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0326436 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0324811 |
| MMP12 | matrix metallopeptidase 12 | 0.0310951 |
| ECT2 | epithelial cell transforming 2 | 0.0310025 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0307595 |
| MED13L | mediator complex subunit 13-like | 0.030473 |
| CENPE | centromere protein E, 312kDa | 0.0303663 |
| GOLGA4 | golgin A4 | 0.0302489 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0302398 |
| RPS12 | ribosomal protein S12 | 0.0299402 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0295389 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0285623 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0280237 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0277708 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0267002 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0262018 |
| OXR1 | oxidation resistance 1 | 0.0261836 |
| RPS27A | ribosomal protein S27a | 0.0261633 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0255346 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.02523 |
| EDN1 | endothelin 1 | 0.0250908 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0249413 |
| PNN | pinin, desmosome associated protein | 0.0245943 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.024576 |
| MGAT4C | MGAT4 family, member C | 0.0245076 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0243471 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0242336 |
| SETD5 | SET domain containing 5 | 0.0242284 |
| EDARADD | EDAR-associated death domain | 0.0240353 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0239845 |
| QKI | QKI, KH domain containing, RNA binding | 0.0238975 |
| PTMS | parathymosin | 0.0237649 |
| CCN2 | cellular communication network factor 2 | 0.0237036 |
| DEPDC1B | DEP domain containing 1B | 0.0236853 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0233513 |
| SCLT1 | sodium channel and clathrin linker 1 | 0.0229323 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 0.0228805 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0225277 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0224826 |
| RPL5 | ribosomal protein L5 | 0.0223945 |
| KLC1 | kinesin light chain 1 | 0.0222234 |
| SPAG9 | sperm associated antigen 9 | 0.0221787 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0218901 |
| RPL23 | ribosomal protein L23 | 0.0215352 |
| HDAC9 | histone deacetylase 9 | 0.021524 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0211648 |
| IL6ST | interleukin 6 signal transducer | 0.0211366 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0211163 |
| PTMA | prothymosin, alpha | 0.0210196 |
| RPL3 | ribosomal protein L3 | 0.0210112 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0207471 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0206352 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0205815 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0205764 |
| DIAPH3 | diaphanous-related formin 3 | 0.0205563 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0205357 |
| MPG | N-methylpurine-DNA glycosylase | 0.0204088 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0203026 |
| CENPF | centromere protein F, 350/400kDa | 0.0201718 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0201271 |
| AXIN2 | axin 2 | 0.0200371 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0199505 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0197741 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0195956 |
| PRR11 | proline rich 11 | 0.0195053 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0192898 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0191745 |
| ETNK1 | ethanolamine kinase 1 | 0.0191301 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0190801 |
| MKI67 | marker of proliferation Ki-67 | 0.0189975 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.301545 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.22617 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.187108 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.096493 |
| ACTG1 | actin gamma 1 | -0.0807151 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.072233 |
| FTL | ferritin, light polypeptide | -0.0719264 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0699092 |
| EHBP1 | EH domain binding protein 1 | -0.0690497 |
| NLGN1 | neuroligin 1 | -0.0671977 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0656274 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.063753 |
| HMGA2 | high mobility group AT-hook 2 | -0.061535 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0553517 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0551576 |
| JMJD1C | jumonji domain containing 1C | -0.0499415 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0498576 |
| HMGA1 | high mobility group AT-hook 1 | -0.0492376 |
| RPL35A | ribosomal protein L35a | -0.0472627 |
| USP34 | ubiquitin specific peptidase 34 | -0.0466098 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0457766 |
| GNAS | GNAS complex locus | -0.0448866 |
| ASPH | aspartate beta-hydroxylase | -0.0445714 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0444775 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0443064 |
| TMSB10 | thymosin beta 10 | -0.0442638 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0436525 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0430331 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0419289 |
| LDHA | lactate dehydrogenase A | -0.0416712 |
| ADIPOR2 | adiponectin receptor 2 | -0.0410336 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0409425 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0390296 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0383406 |
| TMEM41B | transmembrane protein 41B | -0.0369523 |
| PCDH9 | protocadherin 9 | -0.036793 |
| HSPB1 | heat shock 27kDa protein 1 | -0.035939 |
| INTS6 | integrator complex subunit 6 | -0.0351546 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0347836 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0344888 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0342472 |
| CCND1 | cyclin D1 | -0.0333721 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0328369 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0327026 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0323405 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0317632 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0316962 |
| EGR1 | early growth response 1 | -0.0316198 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0314426 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0310468 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0309936 |
| ANK2 | ankyrin 2, neuronal | -0.0307026 |
| RRM2 | ribonucleotide reductase M2 | -0.03042 |
| PRDX1 | peroxiredoxin 1 | -0.0296233 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0294818 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0292486 |
| RPL37 | ribosomal protein L37 | -0.0291863 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0288543 |
| BRI3BP | BRI3 binding protein | -0.0288206 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0287667 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0284134 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0283936 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0281963 |
| EPHA5 | EPH receptor A5 | -0.0281851 |
| LDHB | lactate dehydrogenase B | -0.0277965 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0276982 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0274382 |
| GCG | glucagon | -0.0274127 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0270516 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0270246 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0268631 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0264402 |
| RNF213 | ring finger protein 213 | -0.0261201 |
| NHSL1 | NHS-like 1 | -0.0259873 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0259012 |
| TENM3 | teneurin transmembrane protein 3 | -0.0258179 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0253519 |
| THSD7A | thrombospondin, type I, domain containing 7A | -0.0248442 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0248143 |
| LRRC23 | leucine rich repeat containing 23 | -0.0245025 |
| KSR2 | kinase suppressor of ras 2 | -0.0244475 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0243765 |
| PCDH7 | protocadherin 7 | -0.0241605 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0241445 |
| TMEM123 | transmembrane protein 123 | -0.0240629 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0240044 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0239443 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0238962 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0236354 |
| TPM4 | tropomyosin 4 | -0.0236154 |
| R3HDM2 | R3H domain containing 2 | -0.023544 |
| FHIT | fragile histidine triad | -0.0233995 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0233147 |
| S100A10 | S100 calcium binding protein A10 | -0.0230218 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0227108 |
| DTNB | dystrobrevin, beta | -0.0223867 |
| SMYD3 | SET and MYND domain containing 3 | -0.0223056 |
| TPR | translocated promoter region, nuclear basket protein | -0.0216568 |
| PGK1 | phosphoglycerate kinase 1 | -0.0215627 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0215347 |
