| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.0328943 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0256902 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0252201 |
| FLNA | filamin A, alpha | 0.025075 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0244924 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0229477 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0225033 |
| DOCK5 | dedicator of cytokinesis 5 | 0.022147 |
| PLEC | plectin | 0.0218461 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.021441 |
| EHBP1 | EH domain binding protein 1 | 0.0209744 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0207539 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0201688 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0195286 |
| HMGA2 | high mobility group AT-hook 2 | 0.0189347 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0186068 |
| EFNA5 | ephrin-A5 | 0.0179458 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0169389 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0169114 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0164746 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.016255 |
| AUTS2 | autism susceptibility candidate 2 | 0.0157319 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0153659 |
| LMO7 | LIM domain 7 | 0.0149686 |
| FNIP1 | folliculin interacting protein 1 | 0.014249 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0134348 |
| EGFR | epidermal growth factor receptor | 0.0127678 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0125929 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0125898 |
| ITSN2 | intersectin 2 | 0.0125727 |
| TUBB4B | tubulin, beta 4B class IVb | 0.012572 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0124924 |
| ASPH | aspartate beta-hydroxylase | 0.0121386 |
| DST | dystonin | 0.0120125 |
| INTS6 | integrator complex subunit 6 | 0.0119886 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0119588 |
| DAPK1 | death-associated protein kinase 1 | 0.011498 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0114523 |
| TNS3 | tensin 3 | 0.0114271 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0112465 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0112057 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0111556 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0110639 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0109564 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0109357 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0108744 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0107044 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.010503 |
| ZNF609 | zinc finger protein 609 | 0.0103347 |
| KLC1 | kinesin light chain 1 | 0.0102854 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0102629 |
| AATF | apoptosis antagonizing transcription factor | 0.0102628 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0102574 |
| RPS3A | ribosomal protein S3A | 0.0102545 |
| USP53 | ubiquitin specific peptidase 53 | 0.0102503 |
| DIDO1 | death inducer-obliterator 1 | 0.0101942 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0101514 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.00999428 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.00994993 |
| SFPQ | splicing factor proline/glutamine-rich | 0.00975722 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.00973403 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.00969155 |
| GOLGA3 | golgin A3 | 0.00957338 |
| GOLGB1 | golgin B1 | 0.00942072 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.00938226 |
| PNN | pinin, desmosome associated protein | 0.00936328 |
| AADAC | arylacetamide deacetylase | 0.00924197 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.00894081 |
| FBXO22 | F-box protein 22 | 0.0086978 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00867258 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.00863104 |
| SETX | senataxin | 0.00858483 |
| CAVIN1 | caveolae associated protein 1 | 0.00853718 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.00849929 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00842694 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.00841837 |
| FUS | FUS RNA binding protein | 0.00838291 |
| PMM2 | phosphomannomutase 2 | 0.00834892 |
| FAT1 | FAT atypical cadherin 1 | 0.00831154 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.00821169 |
| NLK | nemo-like kinase | 0.00819646 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00818538 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.00816172 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | 0.00814961 |
| RASAL2 | RAS protein activator like 2 | 0.00805604 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.00796648 |
| NAV3 | neuron navigator 3 | 0.00795875 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.00794763 |
| KDM5C | lysine (K)-specific demethylase 5C | 0.00794614 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.00789663 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.00780286 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.00778587 |
| VCP | valosin containing protein | 0.007776 |
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.00774819 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.00771852 |
| RAD51B | RAD51 paralog B | 0.00770865 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.00767813 |
| UBAP2 | ubiquitin associated protein 2 | 0.00762642 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.00762471 |
| GOSR2 | golgi SNAP receptor complex member 2 | 0.00760853 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.29356 |
| MT2A | metallothionein 2A | -0.218773 |
| FTL | ferritin, light polypeptide | -0.145466 |
| TMSB10 | thymosin beta 10 | -0.14239 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.130822 |
| VIM | vimentin | -0.114065 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0995676 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0965982 |
| ACTG1 | actin gamma 1 | -0.0965123 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0950679 |
| RPLP1 | ribosomal protein, large, P1 | -0.0942251 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0916878 |
| RPS19 | ribosomal protein S19 | -0.0895012 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.089022 |
| MT1X | metallothionein 1X | -0.0879864 |
| LDHA | lactate dehydrogenase A | -0.0874171 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0834492 |
| NDRG1 | N-myc downstream regulated 1 | -0.0782603 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0775709 |
| ANXA2 | annexin A2 | -0.0734803 |
| POTEF | POTE ankyrin domain family, member F | -0.0726818 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.072675 |
| STC1 | stanniocalcin 1 | -0.0690893 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0664167 |
| RPS6 | ribosomal protein S6 | -0.0552152 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0545572 |
| CA12 | carbonic anhydrase XII | -0.0534273 |
| KRT81 | keratin 81, type II | -0.0520373 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0515833 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0496822 |
| RPL35A | ribosomal protein L35a | -0.0493784 |
| USP3 | ubiquitin specific peptidase 3 | -0.0490839 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0480035 |
| TKT | transketolase | -0.0454543 |
| PKM | pyruvate kinase, muscle | -0.0454396 |
| RPS16 | ribosomal protein S16 | -0.0447685 |
| PGK1 | phosphoglycerate kinase 1 | -0.0442188 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0428024 |
| RPL7 | ribosomal protein L7 | -0.0414296 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0413518 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0400432 |
| HMGA1 | high mobility group AT-hook 1 | -0.0393796 |
| PFN1 | profilin 1 | -0.0387903 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0384569 |
| FAM107B | family with sequence similarity 107, member B | -0.0375174 |
| RPS13 | ribosomal protein S13 | -0.0372641 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0371867 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0369842 |
| RPS24 | ribosomal protein S24 | -0.0356961 |
| RTN4 | reticulon 4 | -0.0355827 |
| RPLP0 | ribosomal protein, large, P0 | -0.0351146 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0350923 |
| RPL19 | ribosomal protein L19 | -0.0328809 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0323428 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0322244 |
| B2M | beta-2-microglobulin | -0.0316566 |
| RPS8 | ribosomal protein S8 | -0.0314982 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0306078 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0302366 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0295869 |
| S100A6 | S100 calcium binding protein A6 | -0.0295428 |
| RPL28 | ribosomal protein L28 | -0.0294779 |
| HELZ | helicase with zinc finger | -0.0294742 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0294034 |
| MYADM | myeloid-associated differentiation marker | -0.0293036 |
| EGR1 | early growth response 1 | -0.0291519 |
| RPS5 | ribosomal protein S5 | -0.0290916 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.028436 |
| WDR45B | WD repeat domain 45B | -0.0283402 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0283214 |
| PDE8A | phosphodiesterase 8A | -0.0281734 |
| RPL23 | ribosomal protein L23 | -0.0281677 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.027619 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0271115 |
| S100A10 | S100 calcium binding protein A10 | -0.0269851 |
| RPS29 | ribosomal protein S29 | -0.0267746 |
| RPL12 | ribosomal protein L12 | -0.0265088 |
| ECT2 | epithelial cell transforming 2 | -0.0264615 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0263064 |
| ANGPTL4 | angiopoietin-like 4 | -0.026134 |
| SEPTIN7 | septin 7 | -0.0260039 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.025945 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0257441 |
| RPL8 | ribosomal protein L8 | -0.0256899 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0256892 |
| SMAD3 | SMAD family member 3 | -0.0250182 |
| RPS23 | ribosomal protein S23 | -0.0249515 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0245227 |
| AXL | AXL receptor tyrosine kinase | -0.0244757 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0242285 |
| HIP1 | huntingtin interacting protein 1 | -0.0241901 |
| ENO1 | enolase 1, (alpha) | -0.024144 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0239408 |
| RACK1 | receptor for activated C kinase 1 | -0.0237492 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0237058 |
| ACTN4 | actinin, alpha 4 | -0.0236881 |
| SPAG9 | sperm associated antigen 9 | -0.02345 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0228035 |
| RPL32 | ribosomal protein L32 | -0.0227583 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0225922 |
