| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Docetaxel (Trihydrate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0941444 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0403408 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0357117 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0336686 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0328918 |
| RPL37A | ribosomal protein L37a | 0.0292197 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0286684 |
| NPSR1 | neuropeptide S receptor 1 | 0.0286346 |
| PLEC | plectin | 0.0280851 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0276752 |
| EHBP1 | EH domain binding protein 1 | 0.0268302 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0267242 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0260329 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0259796 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0259458 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.024374 |
| PTK2 | protein tyrosine kinase 2 | 0.023499 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0231454 |
| TXNRD1 | thioredoxin reductase 1 | 0.0230707 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0224261 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0221223 |
| PMM2 | phosphomannomutase 2 | 0.0215356 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0211418 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0197373 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0195956 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0191163 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.019027 |
| FLNA | filamin A, alpha | 0.0190078 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0188912 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0187793 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0187021 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0180073 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) | 0.0179566 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0177157 |
| SET | SET nuclear proto-oncogene | 0.0175744 |
| LMO7 | LIM domain 7 | 0.0175233 |
| NCKAP1 | NCK-associated protein 1 | 0.0169914 |
| SMC3 | structural maintenance of chromosomes 3 | 0.0169251 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0168197 |
| RPLP2 | ribosomal protein, large, P2 | 0.0165907 |
| SLTM | SAFB-like, transcription modulator | 0.0159552 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0159473 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0156543 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | 0.0155867 |
| SIK3 | SIK family kinase 3 | 0.0155332 |
| RASAL2 | RAS protein activator like 2 | 0.0152125 |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.0150278 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0148324 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0147074 |
| RPS3 | ribosomal protein S3 | 0.0146981 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0146939 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0146619 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0145374 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0145143 |
| RPS27A | ribosomal protein S27a | 0.0145018 |
| ANXA3 | annexin A3 | 0.0143594 |
| COL17A1 | collagen, type XVII, alpha 1 | 0.0141463 |
| HMGA2 | high mobility group AT-hook 2 | 0.014109 |
| HDGF | hepatoma-derived growth factor | 0.0139946 |
| RPS3A | ribosomal protein S3A | 0.0139624 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0138942 |
| RPS12 | ribosomal protein S12 | 0.0138857 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0137239 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0137235 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0136606 |
| CTTN | cortactin | 0.0133123 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0132332 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0130943 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0126754 |
| LAMC2 | laminin, gamma 2 | 0.0126694 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.012666 |
| CDK13 | cyclin-dependent kinase 13 | 0.0126193 |
| KLC1 | kinesin light chain 1 | 0.0125954 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.012563 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.0125499 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0125398 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0125016 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0124743 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0124567 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.01244 |
| SAFB2 | scaffold attachment factor B2 | 0.0123573 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0123176 |
| FNIP1 | folliculin interacting protein 1 | 0.0122327 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0122155 |
| AAK1 | AP2 associated kinase 1 | 0.0122123 |
| XYLT1 | xylosyltransferase I | 0.012041 |
| AATF | apoptosis antagonizing transcription factor | 0.0119142 |
| ABHD17C | abhydrolase domain containing 17C | 0.0118232 |
| ZNF706 | zinc finger protein 706 | 0.0118118 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 | 0.0117956 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) | 0.0117776 |
| ILRUN | inflammation and lipid regulator with UBA-like and NBR1-like domains | 0.0114156 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.011358 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.01128 |
| POU2F1 | POU class 2 homeobox 1 | 0.01128 |
| FERMT1 | fermitin family member 1 | 0.0112387 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0111813 |
| KRT18 | keratin 18, type I | 0.0111807 |
| RASA3 | RAS p21 protein activator 3 | 0.0111551 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0111467 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.339066 |
| NDRG1 | N-myc downstream regulated 1 | -0.271169 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.218036 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.171316 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.157345 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.145288 |
| TMSB10 | thymosin beta 10 | -0.123135 |
| LDHA | lactate dehydrogenase A | -0.121139 |
| S100A10 | S100 calcium binding protein A10 | -0.116123 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.109863 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.100984 |
| HMGA1 | high mobility group AT-hook 1 | -0.0992551 |
| POTEF | POTE ankyrin domain family, member F | -0.0989387 |
| SDC4 | syndecan 4 | -0.0959406 |
| VIM | vimentin | -0.0915209 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0854305 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0825391 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0810527 |
| RIOK3 | RIO kinase 3 | -0.0801601 |
| ITGA6 | integrin, alpha 6 | -0.079815 |
| S100A11 | S100 calcium binding protein A11 | -0.0795214 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0781201 |
| ANXA2 | annexin A2 | -0.0776358 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0758504 |
| FAM107B | family with sequence similarity 107, member B | -0.0757305 |
| MUC17 | mucin 17, cell surface associated | -0.0752292 |
| PGK1 | phosphoglycerate kinase 1 | -0.0749179 |
| DSG2 | desmoglein 2 | -0.0744549 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0681254 |
| B2M | beta-2-microglobulin | -0.0662655 |
| EZR | ezrin | -0.0649152 |
| SLC38A2 | solute carrier family 38, member 2 | -0.063035 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0622967 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0617293 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0603655 |
| FAM3C | family with sequence similarity 3, member C | -0.0575636 |
| LAMB3 | laminin, beta 3 | -0.0574469 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | -0.0568484 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0548085 |
| RPL35A | ribosomal protein L35a | -0.0544042 |
| EGR1 | early growth response 1 | -0.0530211 |
| PTMA | prothymosin, alpha | -0.0507546 |
| RTN4 | reticulon 4 | -0.0502156 |
| PERP | PERP, TP53 apoptosis effector | -0.0499238 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0497184 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0486358 |
| RPLP1 | ribosomal protein, large, P1 | -0.0469897 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0468506 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0459858 |
| TXNIP | thioredoxin interacting protein | -0.0445298 |
| SEPTIN7 | septin 7 | -0.0437085 |
| FTL | ferritin, light polypeptide | -0.0434739 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.042946 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0418658 |
| MYO1E | myosin IE | -0.0416526 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0416309 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0409196 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0408504 |
| ACTN4 | actinin, alpha 4 | -0.0406494 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0406459 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0396976 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | -0.0396576 |
| ARHGAP42 | Rho GTPase activating protein 42 | -0.0383803 |
| FOSL1 | FOS-like antigen 1 | -0.0381678 |
| CDCP1 | CUB domain containing protein 1 | -0.0376066 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0375175 |
| EMP1 | epithelial membrane protein 1 | -0.0369538 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0365975 |
| ITGB4 | integrin, beta 4 | -0.036107 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0358077 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0355902 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0353553 |
| PKM | pyruvate kinase, muscle | -0.0351682 |
| FBXO11 | F-box protein 11 | -0.0347649 |
| KRT19 | keratin 19, type I | -0.0344833 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0343597 |
| RPLP0 | ribosomal protein, large, P0 | -0.0329895 |
| S100A6 | S100 calcium binding protein A6 | -0.0325135 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0325103 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0323945 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0322775 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0321715 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0321323 |
| WASF2 | WAS protein family, member 2 | -0.0320055 |
| VCL | vinculin | -0.0319471 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0317272 |
| JMJD1C | jumonji domain containing 1C | -0.0316097 |
| NPTN | neuroplastin | -0.0314903 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0310591 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0309669 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0302289 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0301179 |
| PARD3 | par-3 family cell polarity regulator | -0.0297756 |
| RPL7 | ribosomal protein L7 | -0.0297473 |
| MYOF | myoferlin | -0.0297283 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.029599 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0295858 |
| EFNA5 | ephrin-A5 | -0.0293187 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.029117 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0288179 |
