| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0669828 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0622121 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0390354 |
| NTN4 | netrin 4 | 0.0388418 |
| SLC38A1 | solute carrier family 38, member 1 | 0.038362 |
| S100A8 | S100 calcium binding protein A8 | 0.0375351 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.035708 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0344658 |
| TMSB4X | thymosin beta 4, X-linked | 0.034044 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0281017 |
| USP53 | ubiquitin specific peptidase 53 | 0.0257571 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0247125 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0242883 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.0239782 |
| SET | SET nuclear proto-oncogene | 0.0237767 |
| KAZN | kazrin, periplakin interacting protein | 0.0232038 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.0229061 |
| KLF6 | Kruppel-like factor 6 | 0.022897 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.0228599 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0222917 |
| PDCD5 | programmed cell death 5 | 0.0216105 |
| FUS | FUS RNA binding protein | 0.0214164 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.021355 |
| RPS6 | ribosomal protein S6 | 0.0213299 |
| TCEA2 | transcription elongation factor A (SII), 2 | 0.021293 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0205875 |
| FLNA | filamin A, alpha | 0.0201059 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0199588 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0198493 |
| GRHL1 | grainyhead-like 1 (Drosophila) | 0.0196591 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0193933 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0190466 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.0185704 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0179219 |
| TXNRD1 | thioredoxin reductase 1 | 0.0178513 |
| QKI | QKI, KH domain containing, RNA binding | 0.0177722 |
| CFB | complement factor B | 0.0177441 |
| HDGF | hepatoma-derived growth factor | 0.0173346 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0173336 |
| GPC6 | glypican 6 | 0.01708 |
| RNF114 | ring finger protein 114 | 0.0170672 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0169193 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0166994 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.016645 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.0165785 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0164002 |
| PLEC | plectin | 0.0161234 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0160939 |
| ANKRD30A | ankyrin repeat domain 30A | 0.0159557 |
| CALR | calreticulin | 0.0157201 |
| PPA1 | pyrophosphatase (inorganic) 1 | 0.0154412 |
| CNTNAP2 | contactin associated protein-like 2 | 0.0151948 |
| MT2A | metallothionein 2A | 0.0149563 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 | 0.0149544 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0149334 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0147528 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0146725 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0145287 |
| WDR43 | WD repeat domain 43 | 0.0144611 |
| RPL26 | ribosomal protein L26 | 0.0144288 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0143715 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0143168 |
| FGB | fibrinogen beta chain | 0.0142775 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.013899 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0138852 |
| INSR | insulin receptor | 0.0138024 |
| S100A7 | S100 calcium binding protein A7 | 0.0137315 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0136781 |
| DYNLL2 | dynein, light chain, LC8-type 2 | 0.0135423 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0135361 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.0134882 |
| IFNGR1 | interferon gamma receptor 1 | 0.0134684 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0133085 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0130289 |
| PDAP1 | PDGFA associated protein 1 | 0.0129417 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0129134 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase | 0.0128801 |
| TBX3 | T-box 3 | 0.0128771 |
| RPL7A | ribosomal protein L7a | 0.0128043 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 0.0125894 |
| CASC3 | cancer susceptibility candidate 3 | 0.0124173 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0123469 |
| NUB1 | negative regulator of ubiquitin-like proteins 1 | 0.0123203 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 0.0123147 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0122402 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0121732 |
| NEK6 | NIMA-related kinase 6 | 0.012172 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0121382 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 | 0.0120901 |
| YARS1 | tyrosyl-tRNA synthetase 1 | 0.0120827 |
| XBP1 | X-box binding protein 1 | 0.0120177 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0120086 |
| BCL2L1 | BCL2-like 1 | 0.0119828 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0119213 |
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 0.0118534 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0118236 |
| COL12A1 | collagen, type XII, alpha 1 | 0.0117709 |
| GDPD1 | glycerophosphodiester phosphodiesterase domain containing 1 | 0.0117451 |
| BICRA | BRD4 interacting chromatin remodeling complex associated protein | 0.0117346 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0116193 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.205478 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.148674 |
| RPL19 | ribosomal protein L19 | -0.146657 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.126479 |
| RPL23 | ribosomal protein L23 | -0.115284 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.114098 |
| VMP1 | vacuole membrane protein 1 | -0.100209 |
| NDRG1 | N-myc downstream regulated 1 | -0.08176 |
| LASP1 | LIM and SH3 protein 1 | -0.0747459 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0701727 |
| ENO1 | enolase 1, (alpha) | -0.0697174 |
| DTNA | dystrobrevin, alpha | -0.0685503 |
| NCOA6 | nuclear receptor coactivator 6 | -0.0673255 |
| CLTC | clathrin, heavy chain (Hc) | -0.0671662 |
| POTEF | POTE ankyrin domain family, member F | -0.0661279 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0658175 |
| SBF2 | SET binding factor 2 | -0.0653883 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0651113 |
| CEP250 | centrosomal protein 250kDa | -0.0649426 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0645987 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0623826 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0619851 |
| PTK2 | protein tyrosine kinase 2 | -0.0617562 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0607812 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0604628 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0594381 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.059088 |
| CDK12 | cyclin-dependent kinase 12 | -0.0588705 |
| ACTG1 | actin gamma 1 | -0.0555968 |
| LDHA | lactate dehydrogenase A | -0.0554797 |
| EGFR | epidermal growth factor receptor | -0.0553779 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0538791 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0534739 |
| TMEM123 | transmembrane protein 123 | -0.0531525 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0517512 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0509311 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0508033 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0501331 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0497776 |
| VEGFA | vascular endothelial growth factor A | -0.0492099 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | -0.0491166 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0488148 |
| RPL35A | ribosomal protein L35a | -0.0487873 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | -0.0479283 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0458669 |
| TPD52 | tumor protein D52 | -0.0447716 |
| NF1 | neurofibromin 1 | -0.0446666 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0424623 |
| PKM | pyruvate kinase, muscle | -0.04224 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0419125 |
| MCL1 | myeloid cell leukemia 1 | -0.0411002 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0410647 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0410169 |
| ASPH | aspartate beta-hydroxylase | -0.0409953 |
| TMEM165 | transmembrane protein 165 | -0.0403777 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0397184 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0397095 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0391031 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0389799 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0388909 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0387691 |
| DENND1A | DENN/MADD domain containing 1A | -0.0380477 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0372592 |
| CCNY | cyclin Y | -0.0369927 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0369231 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0367483 |
| ATXN1 | ataxin 1 | -0.0366046 |
| KMT5B | lysine methyltransferase 5B | -0.0366027 |
| ZNF148 | zinc finger protein 148 | -0.0365543 |
| RPS3 | ribosomal protein S3 | -0.0363283 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0360149 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0359228 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.035895 |
| ZNF652 | zinc finger protein 652 | -0.0355869 |
| ZNF292 | zinc finger protein 292 | -0.0347506 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0344953 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | -0.0343736 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0343346 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0341022 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.0339652 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0338749 |
| MMP24OS | MMP24 opposite strand | -0.0332827 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0332366 |
| ANKRD17 | ankyrin repeat domain 17 | -0.033111 |
| USP34 | ubiquitin specific peptidase 34 | -0.0330277 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | -0.0329875 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.032899 |
| TPI1 | triosephosphate isomerase 1 | -0.0328426 |
| RAD51B | RAD51 paralog B | -0.0326517 |
| FAM13A | family with sequence similarity 13, member A | -0.0326442 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0325075 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0321118 |
| AFF1 | AF4/FMR2 family, member 1 | -0.032071 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0317623 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0314805 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0312932 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.031217 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0311762 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0311569 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0311106 |
