| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in C-33 A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_C-33 A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLIT2 | slit homolog 2 (Drosophila) | 0.128628 |
| SHROOM3 | shroom family member 3 | 0.0599665 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | 0.047161 |
| RAD51B | RAD51 paralog B | 0.0445241 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0441047 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0418192 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0416457 |
| FAT1 | FAT atypical cadherin 1 | 0.0390981 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0367906 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0362511 |
| KLHL4 | kelch-like family member 4 | 0.0354707 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0349725 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0329859 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.032015 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0311306 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0306154 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0296837 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0296263 |
| AFG2A | AFG2 AAA ATPase homolog A | 0.028742 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.0284071 |
| TUBB | tubulin, beta class I | 0.0281573 |
| YBX1 | Y box binding protein 1 | 0.0280893 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0273051 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 0.0264148 |
| FMNL2 | formin-like 2 | 0.0264135 |
| CDH18 | cadherin 18, type 2 | 0.0262567 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0258356 |
| CHRM3 | cholinergic receptor, muscarinic 3 | 0.0257904 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0256908 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0255069 |
| ANXA2 | annexin A2 | 0.0253399 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.024989 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.023633 |
| RPLP2 | ribosomal protein, large, P2 | 0.023586 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.02354 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0233213 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0232917 |
| MLIP | muscular LMNA-interacting protein | 0.0232762 |
| RHBDD1 | rhomboid domain containing 1 | 0.0230202 |
| GRID2 | glutamate receptor, ionotropic, delta 2 | 0.022914 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0227146 |
| MGA | MGA, MAX dimerization protein | 0.0225278 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0221994 |
| MTAP | methylthioadenosine phosphorylase | 0.0221509 |
| RANBP17 | RAN binding protein 17 | 0.022092 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0217767 |
| LYRM4 | LYR motif containing 4 | 0.0213859 |
| KCNH5 | potassium channel, voltage gated eag related subfamily H, member 5 | 0.0213227 |
| RPL3 | ribosomal protein L3 | 0.0210881 |
| JUN | jun proto-oncogene | 0.0210767 |
| NOP56 | NOP56 ribonucleoprotein | 0.0210357 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.0208578 |
| THBS1 | thrombospondin 1 | 0.0207789 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.0207066 |
| UBC | ubiquitin C | 0.0205906 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0205022 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0201523 |
| ZRANB3 | zinc finger, RAN-binding domain containing 3 | 0.0201434 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0200439 |
| ADGRA3 | adhesion G protein-coupled receptor A3 | 0.0198142 |
| RPS10 | ribosomal protein S10 | 0.0196627 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0196302 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0195472 |
| LDLRAD3 | low density lipoprotein receptor class A domain containing 3 | 0.0194364 |
| DENND1A | DENN/MADD domain containing 1A | 0.019085 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0190266 |
| PRKD3 | protein kinase D3 | 0.0190093 |
| FLNA | filamin A, alpha | 0.0189426 |
| KLHL5 | kelch-like family member 5 | 0.0189002 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | 0.0187546 |
| MKI67 | marker of proliferation Ki-67 | 0.018663 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0185608 |
| ZNF37A | zinc finger protein 37A | 0.0184515 |
| ZNF121 | zinc finger protein 121 | 0.018377 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0182903 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0182296 |
| E2F3 | E2F transcription factor 3 | 0.0180723 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0180201 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0179681 |
| EWSR1 | EWS RNA-binding protein 1 | 0.017937 |
| TMEM117 | transmembrane protein 117 | 0.0179357 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0178874 |
| CALD1 | caldesmon 1 | 0.017788 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0177628 |
| GTF2F1 | general transcription factor IIF, polypeptide 1, 74kDa | 0.017741 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0175339 |
| CENPE | centromere protein E, 312kDa | 0.0173809 |
| WWC2 | WW and C2 domain containing 2 | 0.0173614 |
| KIF1A | kinesin family member 1A | 0.0173474 |
| RPL4 | ribosomal protein L4 | 0.0172624 |
| TOP1 | topoisomerase (DNA) I | 0.0171182 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0169545 |
| YAP1 | Yes-associated protein 1 | 0.01689 |
| IPO11 | importin 11 | 0.0166785 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0166391 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.016617 |
| FRMD5 | FERM domain containing 5 | 0.0165518 |
| LRRC8D | leucine rich repeat containing 8 family, member D | 0.0163592 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | 0.0162116 |
| TUBB4B | tubulin, beta 4B class IVb | 0.016176 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.122738 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.117843 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0967345 |
| NFIA | nuclear factor I/A | -0.0924841 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0918475 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0879377 |
| ZNF608 | zinc finger protein 608 | -0.0830797 |
| JMJD1C | jumonji domain containing 1C | -0.0791919 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0744879 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0705663 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0701934 |
| PTMA | prothymosin, alpha | -0.0699131 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0687674 |
| USP34 | ubiquitin specific peptidase 34 | -0.0649524 |
| COL5A2 | collagen, type V, alpha 2 | -0.0637713 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0636218 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0633267 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0620522 |
| RPLP1 | ribosomal protein, large, P1 | -0.0604821 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0604598 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.060421 |
| SMYD3 | SET and MYND domain containing 3 | -0.0592423 |
| VCL | vinculin | -0.059188 |
| SETD5 | SET domain containing 5 | -0.059111 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0557599 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0554498 |
| NUP58 | nucleoporin 58 | -0.0549315 |
| MED13 | mediator complex subunit 13 | -0.0547604 |
| HELZ | helicase with zinc finger | -0.0530562 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.052501 |
| SEPTIN7 | septin 7 | -0.0519597 |
| PIAS2 | protein inhibitor of activated STAT, 2 | -0.0514541 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0510833 |
| PGK1 | phosphoglycerate kinase 1 | -0.0501522 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0501257 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0498165 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0496273 |
| RPS2 | ribosomal protein S2 | -0.0488658 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0474615 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0469723 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0466092 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0465715 |
| TPD52 | tumor protein D52 | -0.0463128 |
| HACE1 | HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | -0.0462696 |
| LDHA | lactate dehydrogenase A | -0.0455891 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0451875 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0451799 |
| NKTR | natural killer cell triggering receptor | -0.0451204 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | -0.0441622 |
| RPS21 | ribosomal protein S21 | -0.0439895 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0438693 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.043609 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0435636 |
| ZNF292 | zinc finger protein 292 | -0.0434729 |
| KIAA1958 | KIAA1958 | -0.0432321 |
| CABIN1 | calcineurin binding protein 1 | -0.0428795 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0426817 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0417848 |
| RPS8 | ribosomal protein S8 | -0.0412871 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0410172 |
| NEBL | nebulette | -0.0409405 |
| WDR45B | WD repeat domain 45B | -0.0409233 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0409167 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0408623 |
| PHF21A | PHD finger protein 21A | -0.0408204 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0405657 |
| XPO1 | exportin 1 | -0.0402544 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0400931 |
| NGLY1 | N-glycanase 1 | -0.0397914 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0394364 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0392399 |
| MYO9A | myosin IXA | -0.0392369 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0385737 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0383961 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | -0.0382137 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0380047 |
| YEATS2 | YEATS domain containing 2 | -0.0377684 |
| HIP1 | huntingtin interacting protein 1 | -0.0376441 |
| MED13L | mediator complex subunit 13-like | -0.0376096 |
| PDE8A | phosphodiesterase 8A | -0.037416 |
| CEP95 | centrosomal protein 95kDa | -0.0370601 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0369661 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0365857 |
| ZNF638 | zinc finger protein 638 | -0.0365158 |
| GYS1 | glycogen synthase 1 (muscle) | -0.0365066 |
| RPL7 | ribosomal protein L7 | -0.0360766 |
| SET | SET nuclear proto-oncogene | -0.0358498 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0355492 |
| RPS6 | ribosomal protein S6 | -0.0350599 |
| CEP350 | centrosomal protein 350kDa | -0.0346178 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.034345 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0342744 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0341721 |
| ANKRD36 | ankyrin repeat domain 36 | -0.0339065 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0338414 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0336383 |
| TAOK1 | TAO kinase 1 | -0.033624 |
| CCDC88A | coiled-coil domain containing 88A | -0.033484 |
| PARD3 | par-3 family cell polarity regulator | -0.0334808 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0334708 |
