| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0764234 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0757859 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0568326 |
| MKI67 | marker of proliferation Ki-67 | 0.0446491 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0330564 |
| FLNA | filamin A, alpha | 0.0320402 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0315778 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0305803 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0295969 |
| LAMC2 | laminin, gamma 2 | 0.0292274 |
| TPM3 | tropomyosin 3 | 0.0290179 |
| VEGFA | vascular endothelial growth factor A | 0.0282341 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0271743 |
| RPS12 | ribosomal protein S12 | 0.0266982 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0259852 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.024949 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0241324 |
| CENPF | centromere protein F, 350/400kDa | 0.0233726 |
| MX1 | MX dynamin-like GTPase 1 | 0.0233622 |
| RPL3 | ribosomal protein L3 | 0.0233095 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.022923 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0228994 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0225788 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0221633 |
| HDGF | hepatoma-derived growth factor | 0.0220868 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0220011 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0217198 |
| RPS17 | ribosomal protein S17 | 0.0214413 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0212931 |
| TUBA1B | tubulin, alpha 1b | 0.0209559 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0207417 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0205721 |
| HDAC9 | histone deacetylase 9 | 0.0200042 |
| TGM2 | transglutaminase 2 | 0.0197717 |
| PLEC | plectin | 0.019419 |
| MCL1 | myeloid cell leukemia 1 | 0.0190769 |
| MUC16 | mucin 16, cell surface associated | 0.0186453 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.018565 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0180502 |
| CCNL1 | cyclin L1 | 0.0179188 |
| NRG3 | neuregulin 3 | 0.0177247 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0163924 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0160231 |
| KYNU | kynureninase | 0.0155499 |
| PCDH1 | protocadherin 1 | 0.0153349 |
| DSPP | dentin sialophosphoprotein | 0.0150774 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0149269 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0148474 |
| RPS2 | ribosomal protein S2 | 0.0148297 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0146509 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0144916 |
| HMGA2 | high mobility group AT-hook 2 | 0.0143344 |
| PKM | pyruvate kinase, muscle | 0.014076 |
| MSN | moesin | 0.013987 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0138433 |
| APOL1 | apolipoprotein L, 1 | 0.0137621 |
| C3 | complement component 3 | 0.0134248 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0133517 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0131075 |
| ITGB8 | integrin, beta 8 | 0.0130275 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.012961 |
| VMP1 | vacuole membrane protein 1 | 0.012886 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.012809 |
| FOSL1 | FOS-like antigen 1 | 0.0127804 |
| LAMB1 | laminin, beta 1 | 0.012729 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | 0.0124816 |
| RPL5 | ribosomal protein L5 | 0.0124504 |
| PEG10 | paternally expressed 10 | 0.0124308 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0123648 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0122926 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0122826 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0121485 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0119722 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0119505 |
| STMN1 | stathmin 1 | 0.011847 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0118023 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0117682 |
| PNN | pinin, desmosome associated protein | 0.0117665 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.011721 |
| CFB | complement factor B | 0.0115918 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0115364 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0114604 |
| DST | dystonin | 0.0114189 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0113919 |
| RPL21 | ribosomal protein L21 | 0.0113422 |
| SET | SET nuclear proto-oncogene | 0.0113095 |
| SSRP1 | structure specific recognition protein 1 | 0.0112247 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0111871 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0111175 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0110797 |
| H2BC5 | H2B clustered histone 5 | 0.0110643 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0108307 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0108294 |
| RPL37A | ribosomal protein L37a | 0.0107513 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0107339 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0107286 |
| DUOX2 | dual oxidase 2 | 0.0106924 |
| SLK | STE20-like kinase | 0.0105852 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0105802 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0105757 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.321127 |
| MT2A | metallothionein 2A | -0.231413 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.198898 |
| MT1X | metallothionein 1X | -0.142904 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.13858 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.134491 |
| PTMA | prothymosin, alpha | -0.120393 |
| TMSB10 | thymosin beta 10 | -0.119964 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.111234 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0912128 |
| LAMB3 | laminin, beta 3 | -0.0854125 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0779933 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0779767 |
| ANXA2 | annexin A2 | -0.0778002 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0760836 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0748431 |
| FTL | ferritin, light polypeptide | -0.0725242 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0644398 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0644115 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0623691 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0622332 |
| RBM39 | RNA binding motif protein 39 | -0.0620008 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0605523 |
| NDRG1 | N-myc downstream regulated 1 | -0.0600451 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0599161 |
| PGK1 | phosphoglycerate kinase 1 | -0.056652 |
| B2M | beta-2-microglobulin | -0.0560889 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.054892 |
| MMP7 | matrix metallopeptidase 7 | -0.0534004 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0511491 |
| RPLP1 | ribosomal protein, large, P1 | -0.0504101 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0493367 |
| FAM13A | family with sequence similarity 13, member A | -0.0489985 |
| OGA | O-GlcNAcase | -0.0486455 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0481804 |
| CCNY | cyclin Y | -0.0478515 |
| RPL35A | ribosomal protein L35a | -0.0471963 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0470928 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0468411 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0462568 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0428326 |
| HLA-B | major histocompatibility complex, class I, B | -0.0428144 |
| CD2AP | CD2-associated protein | -0.0424898 |
| H1-0 | H1.0 linker histone | -0.0422159 |
| AHNAK | AHNAK nucleoprotein | -0.0420295 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.041912 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0411893 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0411072 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0402805 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0395634 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0392164 |
| TOP1 | topoisomerase (DNA) I | -0.0392153 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0391508 |
| RIOK3 | RIO kinase 3 | -0.0388309 |
| LDHA | lactate dehydrogenase A | -0.0385225 |
| RTN4 | reticulon 4 | -0.0379841 |
| RLF | rearranged L-myc fusion | -0.0373979 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0369919 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0368915 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0368089 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.03664 |
| HMGA1 | high mobility group AT-hook 1 | -0.0364076 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0363744 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.036047 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0359394 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0355459 |
| WDR45B | WD repeat domain 45B | -0.0351028 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0349423 |
| LMAN1 | lectin, mannose-binding, 1 | -0.034766 |
| TMEM263 | transmembrane protein 263 | -0.034753 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0344979 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0342966 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0339558 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0334615 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0334108 |
| TMEM123 | transmembrane protein 123 | -0.0330925 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0328778 |
| LMO7 | LIM domain 7 | -0.0325905 |
| GNAS | GNAS complex locus | -0.0325133 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0321305 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0320326 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0320258 |
| TXNIP | thioredoxin interacting protein | -0.0316718 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0315672 |
| IER3 | immediate early response 3 | -0.0312 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0311953 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.03103 |
| YME1L1 | YME1-like 1 ATPase | -0.0308019 |
| MEF2A | myocyte enhancer factor 2A | -0.0305531 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0304779 |
| DSG2 | desmoglein 2 | -0.0304604 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0302955 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.030162 |
| CSTB | cystatin B (stefin B) | -0.0299598 |
| EREG | epiregulin | -0.0296126 |
| FAM162A | family with sequence similarity 162, member A | -0.0295429 |
| ZNF292 | zinc finger protein 292 | -0.0293074 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0292178 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0287881 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0287823 |
