| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.108243 |
| FMN1 | formin 1 | 0.0942311 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0840189 |
| LSAMP | limbic system-associated membrane protein | 0.0719537 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0528997 |
| TLE4 | transducin-like enhancer of split 4 | 0.0471227 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0440502 |
| GLCCI1 | glucocorticoid induced 1 | 0.0439246 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0426779 |
| LPIN1 | lipin 1 | 0.0417858 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0368508 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0356339 |
| TPM1 | tropomyosin 1 (alpha) | 0.0338498 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0332262 |
| THBS1 | thrombospondin 1 | 0.0321333 |
| PDZRN3 | PDZ domain containing ring finger 3 | 0.0295197 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0289294 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0287717 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.02868 |
| VMP1 | vacuole membrane protein 1 | 0.0277065 |
| PRKCA | protein kinase C, alpha | 0.0274668 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0265819 |
| UNC5C | unc-5 homolog C (C. elegans) | 0.0261547 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0251874 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0251525 |
| SET | SET nuclear proto-oncogene | 0.0249464 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0246209 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0246205 |
| STK38L | serine/threonine kinase 38 like | 0.0245298 |
| FERMT2 | fermitin family member 2 | 0.0240355 |
| RNF213 | ring finger protein 213 | 0.0238305 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0232487 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0232105 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0229117 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.022644 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.022075 |
| TPM4 | tropomyosin 4 | 0.0219989 |
| FAM13B | family with sequence similarity 13, member B | 0.0218605 |
| TENM4 | teneurin transmembrane protein 4 | 0.0214211 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.0212449 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0208582 |
| OLA1 | Obg-like ATPase 1 | 0.0208551 |
| FRMD4A | FERM domain containing 4A | 0.0206842 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0202392 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0199087 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0196961 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.019602 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0195153 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0192055 |
| FLNA | filamin A, alpha | 0.0189411 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0188525 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0185185 |
| MED13L | mediator complex subunit 13-like | 0.0184037 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0183589 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0183482 |
| GAB2 | GRB2-associated binding protein 2 | 0.0182302 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | 0.0181887 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0181844 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0181273 |
| CDC27 | cell division cycle 27 | 0.0180185 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0179357 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0179349 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0178633 |
| MAP4 | microtubule-associated protein 4 | 0.0177842 |
| LRP1B | low density lipoprotein receptor-related protein 1B | 0.0177018 |
| MX2 | MX dynamin-like GTPase 2 | 0.0174722 |
| RAD51B | RAD51 paralog B | 0.0173746 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0172672 |
| MRTFA | myocardin related transcription factor A | 0.0170382 |
| JMJD1C | jumonji domain containing 1C | 0.0170005 |
| MALT1 | MALT1 paracaspase | 0.016994 |
| SETD2 | SET domain containing 2 | 0.0167126 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.016657 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0166339 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0165767 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0164518 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A | 0.0162705 |
| RSU1 | Ras suppressor protein 1 | 0.0162213 |
| KLHL13 | kelch-like family member 13 | 0.0160773 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0160196 |
| CUX2 | cut-like homeobox 2 | 0.0159794 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0159443 |
| PRKD3 | protein kinase D3 | 0.0158807 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0157823 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0156468 |
| AUTS2 | autism susceptibility candidate 2 | 0.0155175 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0155153 |
| SP100 | SP100 nuclear antigen | 0.0154557 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0154002 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0153556 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0153376 |
| RPS2 | ribosomal protein S2 | 0.0152862 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like | 0.0152758 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0152523 |
| PNN | pinin, desmosome associated protein | 0.0151711 |
| FOXO3 | forkhead box O3 | 0.0151354 |
| SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 | 0.0151055 |
| RET | ret proto-oncogene | 0.0150864 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0150679 |
| MSI2 | musashi RNA-binding protein 2 | 0.0150492 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.452447 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.193861 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.143413 |
| NDRG1 | N-myc downstream regulated 1 | -0.0954732 |
| VIM | vimentin | -0.0894248 |
| GDF15 | growth differentiation factor 15 | -0.0756508 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.075613 |
| NRG1 | neuregulin 1 | -0.0741561 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0741303 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0675662 |
| ACTG1 | actin gamma 1 | -0.0665473 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0644751 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0624717 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0594223 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0586943 |
| RPL35A | ribosomal protein L35a | -0.0553079 |
| IER3 | immediate early response 3 | -0.0533248 |
| RTN4 | reticulon 4 | -0.0509805 |
| STC1 | stanniocalcin 1 | -0.0507244 |
| B2M | beta-2-microglobulin | -0.0501994 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0486039 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0471501 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.046845 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0466552 |
| RPS24 | ribosomal protein S24 | -0.0465303 |
| ENO1 | enolase 1, (alpha) | -0.0458375 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0458091 |
| WDR45B | WD repeat domain 45B | -0.0443652 |
| RPS6 | ribosomal protein S6 | -0.0428546 |
| PTMA | prothymosin, alpha | -0.0428447 |
| MEF2A | myocyte enhancer factor 2A | -0.0422765 |
| RPS8 | ribosomal protein S8 | -0.0421851 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0412787 |
| RPL34 | ribosomal protein L34 | -0.0407238 |
| FNBP1 | formin binding protein 1 | -0.0405964 |
| USP34 | ubiquitin specific peptidase 34 | -0.0404624 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0404083 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0400395 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0398361 |
| HMGA1 | high mobility group AT-hook 1 | -0.039154 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0389906 |
| S100A6 | S100 calcium binding protein A6 | -0.0387438 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0385473 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0382976 |
| RPLP0 | ribosomal protein, large, P0 | -0.0381886 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0374322 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0373682 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0371361 |
| RPLP1 | ribosomal protein, large, P1 | -0.0361717 |
| EFNA5 | ephrin-A5 | -0.0338875 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0338841 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.033331 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0331706 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0329381 |
| RPL11 | ribosomal protein L11 | -0.032642 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0325053 |
| BPTF | bromodomain PHD finger transcription factor | -0.0319596 |
| SYT1 | synaptotagmin I | -0.030822 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0305712 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0301261 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0300769 |
| HMGA2 | high mobility group AT-hook 2 | -0.0297839 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0296975 |
| RPL19 | ribosomal protein L19 | -0.0295322 |
| ANGPT1 | angiopoietin 1 | -0.0295282 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0289576 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0287941 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.028786 |
| LDHA | lactate dehydrogenase A | -0.0287228 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0285606 |
| PGK1 | phosphoglycerate kinase 1 | -0.0285432 |
| GLG1 | golgi glycoprotein 1 | -0.0283472 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0282479 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0280827 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0280595 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0280278 |
| SRP72 | signal recognition particle 72kDa | -0.0279967 |
| SETD5 | SET domain containing 5 | -0.0279157 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0278934 |
| MTDH | metadherin | -0.0275608 |
| GOLGA4 | golgin A4 | -0.0273685 |
| ZNF292 | zinc finger protein 292 | -0.0273272 |
| COL1A1 | collagen, type I, alpha 1 | -0.0270226 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0268517 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0268009 |
| COPA | coatomer protein complex, subunit alpha | -0.0266399 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.026497 |
| TOB1 | transducer of ERBB2, 1 | -0.0264765 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0263055 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0259866 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.025986 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.025983 |
| KIAA1217 | KIAA1217 | -0.0259757 |
| NCAM2 | neural cell adhesion molecule 2 | -0.025679 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0254938 |
| RPS25 | ribosomal protein S25 | -0.0253474 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0250666 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0249593 |
| MAP1B | microtubule-associated protein 1B | -0.0245895 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.024325 |
