| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.365527 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.180597 |
| FN1 | fibronectin 1 | 0.13982 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0876127 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0618494 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0603575 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0575892 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0549714 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.049994 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0417841 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.040171 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0397875 |
| VCAN | versican | 0.0393176 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0376048 |
| TUBB | tubulin, beta class I | 0.0364459 |
| RPLP2 | ribosomal protein, large, P2 | 0.0344027 |
| ADM | adrenomedullin | 0.0333349 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.030757 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0300494 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0293285 |
| KIAA1217 | KIAA1217 | 0.0292388 |
| CADM1 | cell adhesion molecule 1 | 0.0290545 |
| MKI67 | marker of proliferation Ki-67 | 0.0281581 |
| UBC | ubiquitin C | 0.0273705 |
| IL6 | interleukin 6 | 0.027167 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 | 0.0264766 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.026442 |
| TMSB10 | thymosin beta 10 | 0.0259244 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0251495 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0249743 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.024951 |
| RPL19 | ribosomal protein L19 | 0.0246526 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0243923 |
| NRP1 | neuropilin 1 | 0.0241291 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.024064 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0231955 |
| IL6ST | interleukin 6 signal transducer | 0.0231649 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0220704 |
| RPS27A | ribosomal protein S27a | 0.0212305 |
| TUBA1B | tubulin, alpha 1b | 0.0209864 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0208074 |
| RPS19 | ribosomal protein S19 | 0.0208051 |
| H1-0 | H1.0 linker histone | 0.02057 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0204988 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0199327 |
| ITGA11 | integrin, alpha 11 | 0.019897 |
| CFB | complement factor B | 0.0197481 |
| RPL23 | ribosomal protein L23 | 0.0193208 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0188294 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0188117 |
| RPS12 | ribosomal protein S12 | 0.0186886 |
| MYO1B | myosin IB | 0.0186118 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0185765 |
| FLNA | filamin A, alpha | 0.0183818 |
| ARRDC3 | arrestin domain containing 3 | 0.0183763 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0182726 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0177243 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0173955 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0173379 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0170665 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0170292 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0167803 |
| RAB13 | RAB13, member RAS oncogene family | 0.0166962 |
| IL1B | interleukin 1, beta | 0.0166295 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0157886 |
| CENPF | centromere protein F, 350/400kDa | 0.0157818 |
| RPL3 | ribosomal protein L3 | 0.0154252 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0148898 |
| ATP13A3 | ATPase type 13A3 | 0.0147634 |
| EBF1 | early B-cell factor 1 | 0.0145817 |
| SP100 | SP100 nuclear antigen | 0.0143036 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.014014 |
| ATL1 | atlastin GTPase 1 | 0.0139691 |
| PTTG1 | pituitary tumor-transforming 1 | 0.0137865 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0137512 |
| IER3 | immediate early response 3 | 0.0135958 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.0135877 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0134609 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0133722 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0133351 |
| MX1 | MX dynamin-like GTPase 1 | 0.0133109 |
| RIGI | RNA sensor RIG-I | 0.0132947 |
| RPL38 | ribosomal protein L38 | 0.0131741 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.013078 |
| SULF1 | sulfatase 1 | 0.0130774 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0130608 |
| TENM1 | teneurin transmembrane protein 1 | 0.0129937 |
| DNER | delta/notch-like EGF repeat containing | 0.0129856 |
| ZMAT4 | zinc finger, matrin-type 4 | 0.0129438 |
| ETV6 | ets variant 6 | 0.0129211 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0128374 |
| RPLP0 | ribosomal protein, large, P0 | 0.0128337 |
| ZFPM2 | zinc finger protein, FOG family member 2 | 0.0126411 |
| TXNRD1 | thioredoxin reductase 1 | 0.0126202 |
| CKAP2 | cytoskeleton associated protein 2 | 0.012593 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0124272 |
| TENM3 | teneurin transmembrane protein 3 | 0.0121508 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.012112 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0120876 |
| CALR | calreticulin | 0.0120661 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.254924 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.211315 |
| EXT1 | exostosin glycosyltransferase 1 | -0.153621 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.146517 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.109793 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.109546 |
| COL1A1 | collagen, type I, alpha 1 | -0.107541 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0871172 |
| LDHA | lactate dehydrogenase A | -0.0845064 |
| VIM | vimentin | -0.0798392 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0772308 |
| ASPH | aspartate beta-hydroxylase | -0.0768754 |
| COL5A1 | collagen, type V, alpha 1 | -0.0765729 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0755877 |
| LOXL2 | lysyl oxidase-like 2 | -0.0750243 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0747851 |
| MT2A | metallothionein 2A | -0.0724718 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.064155 |
| FBN1 | fibrillin 1 | -0.0630407 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0621373 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0573751 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0571978 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.056987 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.051578 |
| VEGFA | vascular endothelial growth factor A | -0.051486 |
| GOLGB1 | golgin B1 | -0.0493577 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0491585 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0476256 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0465118 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0458812 |
| PDE10A | phosphodiesterase 10A | -0.0458149 |
| SDC2 | syndecan 2 | -0.0455328 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0455109 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0434527 |
| LMAN1 | lectin, mannose-binding, 1 | -0.043335 |
| NAV1 | neuron navigator 1 | -0.0413305 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0410948 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0398516 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.039466 |
| ACTG1 | actin gamma 1 | -0.039008 |
| ECE1 | endothelin converting enzyme 1 | -0.0379238 |
| MAP4 | microtubule-associated protein 4 | -0.0378277 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.037168 |
| RRBP1 | ribosome binding protein 1 | -0.0369155 |
| MTDH | metadherin | -0.0368757 |
| PGK1 | phosphoglycerate kinase 1 | -0.0367689 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0364137 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0363484 |
| LOX | lysyl oxidase | -0.0363472 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.036215 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0348001 |
| VCL | vinculin | -0.0346212 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0339118 |
| CALD1 | caldesmon 1 | -0.0337126 |
| TRAM1 | translocation associated membrane protein 1 | -0.0332756 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0331955 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0326639 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0324847 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0321478 |
| MYO10 | myosin X | -0.0318345 |
| SMYD3 | SET and MYND domain containing 3 | -0.0313052 |
| CD44 | CD44 molecule (Indian blood group) | -0.030902 |
| GOLGA4 | golgin A4 | -0.0307692 |
| CLTC | clathrin, heavy chain (Hc) | -0.0303826 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0301709 |
| MAP1B | microtubule-associated protein 1B | -0.0299521 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0295852 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0293017 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0292116 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.029008 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0289611 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.02862 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0284758 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0282106 |
| RPS2 | ribosomal protein S2 | -0.0281928 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0278115 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0276071 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.027335 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0270075 |
| B2M | beta-2-microglobulin | -0.0269677 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0267681 |
| CMIP | c-Maf inducing protein | -0.0265815 |
| SEC24A | SEC24 family member A | -0.0265655 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0263878 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0263348 |
| AHNAK | AHNAK nucleoprotein | -0.0262627 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.026159 |
| TMF1 | TATA element modulatory factor 1 | -0.0260984 |
| COL1A2 | collagen, type I, alpha 2 | -0.0257451 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0256159 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0250035 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0248365 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0246776 |
| RASA2 | RAS p21 protein activator 2 | -0.0246617 |
| TMEM165 | transmembrane protein 165 | -0.024231 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0239369 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0238996 |
| SBF2 | SET binding factor 2 | -0.0238698 |
| SEC24D | SEC24 family member D | -0.0235067 |
| HM13 | histocompatibility (minor) 13 | -0.0234798 |
