| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.120305 |
| TXNRD1 | thioredoxin reductase 1 | 0.0571372 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0545979 |
| MKI67 | marker of proliferation Ki-67 | 0.053966 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.045567 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0430361 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0426725 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0421973 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0388579 |
| OGA | O-GlcNAcase | 0.0384428 |
| GOLGA4 | golgin A4 | 0.0374604 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0353897 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0349964 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0348115 |
| CENPF | centromere protein F, 350/400kDa | 0.0347836 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0346558 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0329449 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0310943 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0304766 |
| XPO1 | exportin 1 | 0.0301422 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0291767 |
| HMGB2 | high mobility group box 2 | 0.0274705 |
| RBM25 | RNA binding motif protein 25 | 0.0263201 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0261378 |
| MATR3 | matrin 3 | 0.0259477 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0257747 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | 0.0257311 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0247942 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0245892 |
| ZNF292 | zinc finger protein 292 | 0.0245478 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0244941 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0241169 |
| KIF5B | kinesin family member 5B | 0.0237129 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0235424 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0229394 |
| TPX2 | TPX2, microtubule-associated | 0.0222128 |
| KIF20B | kinesin family member 20B | 0.021432 |
| HMGB1 | high mobility group box 1 | 0.0212756 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0211155 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0207156 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0204456 |
| CENPE | centromere protein E, 312kDa | 0.020354 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0202302 |
| TPR | translocated promoter region, nuclear basket protein | 0.0200594 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0195168 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0194603 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0193328 |
| CTTN | cortactin | 0.0193258 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0191052 |
| CANX | calnexin | 0.0190528 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0190405 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0185066 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0185006 |
| CCAR1 | cell division cycle and apoptosis regulator 1 | 0.0182731 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0182429 |
| FNBP4 | formin binding protein 4 | 0.0180858 |
| CBX3 | chromobox homolog 3 | 0.0178512 |
| RBM27 | RNA binding motif protein 27 | 0.0178392 |
| ARHGAP11A | Rho GTPase activating protein 11A | 0.0176843 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0176705 |
| NCKAP1 | NCK-associated protein 1 | 0.0176643 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0173808 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0173415 |
| TOP1 | topoisomerase (DNA) I | 0.0173378 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0172908 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0172062 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0170399 |
| NOP58 | NOP58 ribonucleoprotein | 0.0170138 |
| THOC2 | THO complex 2 | 0.0169457 |
| MYL12B | myosin, light chain 12B, regulatory | 0.0168627 |
| RPS27A | ribosomal protein S27a | 0.0167951 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0166965 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0162979 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0162187 |
| PRC1 | protein regulator of cytokinesis 1 | 0.0161751 |
| PDS5B | PDS5 cohesin associated factor B | 0.0161452 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0161259 |
| NUP58 | nucleoporin 58 | 0.0160715 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0160382 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.016002 |
| RPS24 | ribosomal protein S24 | 0.0158697 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | 0.0158601 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0157295 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0155891 |
| TMSB4X | thymosin beta 4, X-linked | 0.0155882 |
| TCERG1 | transcription elongation regulator 1 | 0.0154318 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0153787 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0153489 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0151107 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0151068 |
| KIF4A | kinesin family member 4A | 0.0150917 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0150278 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0150176 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0149642 |
| SARNP | SAP domain containing ribonucleoprotein | 0.0148614 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0148457 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0148109 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0147869 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0146159 |
| TNPO1 | transportin 1 | 0.0145673 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH14 | myosin, heavy chain 14, non-muscle | -0.169566 |
| NDRG1 | N-myc downstream regulated 1 | -0.165111 |
| KRT20 | keratin 20, type I | -0.134777 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.127325 |
| EXT1 | exostosin glycosyltransferase 1 | -0.12073 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.118546 |
| SMAD3 | SMAD family member 3 | -0.114272 |
| LMO7 | LIM domain 7 | -0.109177 |
| FRY | furry homolog (Drosophila) | -0.108676 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.102741 |
| TJP1 | tight junction protein 1 | -0.102099 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0947341 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0934063 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.092532 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0920522 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0916418 |
| EZR | ezrin | -0.0893536 |
| INTS6 | integrator complex subunit 6 | -0.0877337 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0857526 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0855791 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0823465 |
| ATXN1 | ataxin 1 | -0.0822803 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0775374 |
| EGR1 | early growth response 1 | -0.0746751 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.073915 |
| LAMA4 | laminin, alpha 4 | -0.0738065 |
| FTL | ferritin, light polypeptide | -0.0730701 |
| LDHA | lactate dehydrogenase A | -0.0728384 |
| ACTN4 | actinin, alpha 4 | -0.0701432 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0694607 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0667808 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0658632 |
| ANXA2 | annexin A2 | -0.0650391 |
| TRIB1 | tribbles pseudokinase 1 | -0.0649324 |
| MYO1E | myosin IE | -0.0642759 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0629782 |
| TMEM65 | transmembrane protein 65 | -0.0623461 |
| KRT8 | keratin 8, type II | -0.0607109 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0604056 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0597774 |
| CTBP2 | C-terminal binding protein 2 | -0.0589004 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0576986 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0573835 |
| POF1B | premature ovarian failure, 1B | -0.0567977 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0562653 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0553871 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0550586 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0546544 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0546439 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0533494 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.052849 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0518744 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.051477 |
| VCL | vinculin | -0.0511087 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0496314 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0494792 |
| AREG | amphiregulin | -0.0488327 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0472353 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0463902 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.045957 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0450777 |
| KRT19 | keratin 19, type I | -0.0450741 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0449745 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0449477 |
| AHNAK | AHNAK nucleoprotein | -0.0447252 |
| PGK1 | phosphoglycerate kinase 1 | -0.0443413 |
| LYZ | lysozyme | -0.0442776 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0430348 |
| PPARD | peroxisome proliferator-activated receptor delta | -0.0423797 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0423361 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0410801 |
| PRELID2 | PRELI domain containing 2 | -0.0404465 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0397241 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0394776 |
| FHL2 | four and a half LIM domains 2 | -0.0390851 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0378542 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0372297 |
| PCED1B | PC-esterase domain containing 1B | -0.0370896 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0369477 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0369446 |
| DGKH | diacylglycerol kinase, eta | -0.0366726 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0360488 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0358017 |
| ETV6 | ets variant 6 | -0.0356928 |
| PRR5L | proline rich 5 like | -0.0355603 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0353977 |
| GSN | gelsolin | -0.0353911 |
| UTRN | utrophin | -0.0352304 |
| FOXO3 | forkhead box O3 | -0.0340855 |
| VMP1 | vacuole membrane protein 1 | -0.0340535 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0337617 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.033585 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0327955 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0324844 |
| JUN | jun proto-oncogene | -0.0322854 |
| POTEF | POTE ankyrin domain family, member F | -0.0321956 |
| RNF213 | ring finger protein 213 | -0.0321061 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0319542 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0313061 |
| TMEM123 | transmembrane protein 123 | -0.0307219 |
