| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSPP | dentin sialophosphoprotein | 0.0638262 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0519075 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0471721 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0429395 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0410785 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0409555 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0384918 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0322916 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0297257 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0283462 |
| EHBP1 | EH domain binding protein 1 | 0.0278103 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0244161 |
| ENAH | enabled homolog (Drosophila) | 0.0232476 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0227547 |
| C3 | complement component 3 | 0.0222488 |
| PTMA | prothymosin, alpha | 0.0220525 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0214951 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0213134 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0205459 |
| TPM4 | tropomyosin 4 | 0.0197762 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0193359 |
| KIF5B | kinesin family member 5B | 0.0192027 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0191159 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0188165 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.018379 |
| RPS6 | ribosomal protein S6 | 0.0183332 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0182042 |
| PEG3 | paternally expressed 3 | 0.0180508 |
| DST | dystonin | 0.0174786 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0169598 |
| MATR3 | matrin 3 | 0.016807 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0167978 |
| MKI67 | marker of proliferation Ki-67 | 0.0165547 |
| GOLGA4 | golgin A4 | 0.0164839 |
| HLF | hepatic leukemia factor | 0.016481 |
| RPL26 | ribosomal protein L26 | 0.0164072 |
| ACSS3 | acyl-CoA synthetase short-chain family member 3 | 0.0161417 |
| CANX | calnexin | 0.0159757 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0158832 |
| HDGF | hepatoma-derived growth factor | 0.015881 |
| MAP1B | microtubule-associated protein 1B | 0.0157843 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0156345 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0152785 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0149175 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0147925 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0146729 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0145001 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0144466 |
| OSMR | oncostatin M receptor | 0.0143093 |
| LAMB1 | laminin, beta 1 | 0.0142098 |
| ZFHX3 | zinc finger homeobox 3 | 0.0140641 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0140394 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0139794 |
| CENPF | centromere protein F, 350/400kDa | 0.0139132 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0139032 |
| ZNF292 | zinc finger protein 292 | 0.0138349 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0137918 |
| CALD1 | caldesmon 1 | 0.0137912 |
| RPS27A | ribosomal protein S27a | 0.0136789 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0136576 |
| PCM1 | pericentriolar material 1 | 0.0134471 |
| CTSB | cathepsin B | 0.0132002 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0131093 |
| FNBP1L | formin binding protein 1-like | 0.0130894 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.012975 |
| APP | amyloid beta (A4) precursor protein | 0.0129594 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0128993 |
| APOE | apolipoprotein E | 0.0128138 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0127757 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0127409 |
| RRBP1 | ribosome binding protein 1 | 0.012717 |
| SFTPA2 | surfactant protein A2 | 0.012685 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0126762 |
| CFB | complement factor B | 0.0125577 |
| SET | SET nuclear proto-oncogene | 0.0123306 |
| UBC | ubiquitin C | 0.0122651 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0121663 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0121354 |
| BPTF | bromodomain PHD finger transcription factor | 0.0120746 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0120542 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0120245 |
| SEPTIN2 | septin 2 | 0.0120226 |
| CALR | calreticulin | 0.011958 |
| ABI1 | abl-interactor 1 | 0.0117684 |
| KIF1B | kinesin family member 1B | 0.0116414 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0116175 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0115148 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0113202 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.0112713 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0112413 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0111375 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0111104 |
| RPL14 | ribosomal protein L14 | 0.0110915 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0110689 |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.0110547 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0109506 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.010863 |
| SLK | STE20-like kinase | 0.0108459 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0108208 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0107527 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.358583 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.111717 |
| MT2A | metallothionein 2A | -0.104227 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0917703 |
| FN1 | fibronectin 1 | -0.0831725 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0723598 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0571605 |
| IGF2 | insulin-like growth factor 2 | -0.0534027 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0504472 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0480543 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0396599 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0392197 |
| FTL | ferritin, light polypeptide | -0.0384312 |
| ATXN1 | ataxin 1 | -0.0378211 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0365087 |
| NDRG1 | N-myc downstream regulated 1 | -0.0334197 |
| VCL | vinculin | -0.0332506 |
| AHSG | alpha-2-HS-glycoprotein | -0.0328416 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0321999 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0295274 |
| APOA2 | apolipoprotein A-II | -0.0290679 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0290526 |
| FOXP1 | forkhead box P1 | -0.0280893 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0274036 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0270768 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.026881 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0257022 |
| INTS6 | integrator complex subunit 6 | -0.0254732 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0246186 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0240428 |
| MCL1 | myeloid cell leukemia 1 | -0.0234227 |
| RUNX1 | runt-related transcription factor 1 | -0.0227059 |
| EGR1 | early growth response 1 | -0.0225909 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0222841 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0218659 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.021609 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0215482 |
| POTEF | POTE ankyrin domain family, member F | -0.020605 |
| RPLP1 | ribosomal protein, large, P1 | -0.020351 |
| USP34 | ubiquitin specific peptidase 34 | -0.0201747 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0200781 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0198991 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0196365 |
| RPL35A | ribosomal protein L35a | -0.0193648 |
| TLE4 | transducin-like enhancer of split 4 | -0.0189649 |
| RPL36 | ribosomal protein L36 | -0.0187013 |
| HMGA1 | high mobility group AT-hook 1 | -0.0185144 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0177697 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0176604 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0175964 |
| TOP1 | topoisomerase (DNA) I | -0.0171938 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.017111 |
| PARD3 | par-3 family cell polarity regulator | -0.016973 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.01667 |
| HPCAL1 | hippocalcin-like 1 | -0.0163828 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0162122 |
| LDHA | lactate dehydrogenase A | -0.0161697 |
| GPC3 | glypican 3 | -0.0161529 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0161127 |
| MYO1E | myosin IE | -0.0158655 |
| NABP1 | nucleic acid binding protein 1 | -0.0157992 |
| ATP10A | ATPase, class V, type 10A | -0.0157548 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0153753 |
| PRKCA | protein kinase C, alpha | -0.0147032 |
| RPS5 | ribosomal protein S5 | -0.0146509 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0146318 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0144801 |
| SVIL | supervillin | -0.0144114 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0143573 |
| APOA1 | apolipoprotein A-I | -0.0142192 |
| GK | glycerol kinase | -0.0141908 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0139776 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.013909 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0138059 |
| SERTAD2 | SERTA domain containing 2 | -0.0137637 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0136931 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.013588 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0134364 |
| PKM | pyruvate kinase, muscle | -0.0133202 |
| STK17A | serine/threonine kinase 17a | -0.0133172 |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | -0.0132899 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0132772 |
| LPIN2 | lipin 2 | -0.0132575 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0132566 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | -0.0132488 |
| FOXO3 | forkhead box O3 | -0.0132014 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0130764 |
| BRD4 | bromodomain containing 4 | -0.0130387 |
| RYBP | RING1 and YY1 binding protein | -0.012852 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0128477 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0125347 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0125322 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0124948 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0124504 |
| TAPBP | TAP binding protein (tapasin) | -0.0124229 |
| VEGFA | vascular endothelial growth factor A | -0.0124199 |
| FOXN3 | forkhead box N3 | -0.0123575 |
| FLNB | filamin B, beta | -0.0123272 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0122982 |
| JAG1 | jagged 1 | -0.0122873 |
