| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLU | clusterin | 0.0604424 |
| RPS6 | ribosomal protein S6 | 0.0502718 |
| PTMA | prothymosin, alpha | 0.0472968 |
| GOLGA4 | golgin A4 | 0.0424749 |
| RPLP2 | ribosomal protein, large, P2 | 0.0368099 |
| IGF2 | insulin-like growth factor 2 | 0.0367971 |
| SQLE | squalene epoxidase | 0.0282443 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0272905 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0254991 |
| MEF2A | myocyte enhancer factor 2A | 0.0226551 |
| H1-0 | H1.0 linker histone | 0.0209176 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0207503 |
| RPL21 | ribosomal protein L21 | 0.0202193 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0198129 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0197339 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0194749 |
| RPL12 | ribosomal protein L12 | 0.0194376 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0194204 |
| RPS8 | ribosomal protein S8 | 0.0194059 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0189919 |
| ADM | adrenomedullin | 0.0181943 |
| DSTN | destrin (actin depolymerizing factor) | 0.0181762 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0180768 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0178648 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0178586 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0175133 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0174855 |
| RPS25 | ribosomal protein S25 | 0.017341 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0170996 |
| SLK | STE20-like kinase | 0.0170365 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.016754 |
| FOSL1 | FOS-like antigen 1 | 0.016638 |
| RPL3 | ribosomal protein L3 | 0.0161701 |
| RPL37A | ribosomal protein L37a | 0.0160303 |
| VIM | vimentin | 0.0158696 |
| TUBA1B | tubulin, alpha 1b | 0.0157214 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0154111 |
| RNF145 | ring finger protein 145 | 0.0151023 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.014858 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0147221 |
| RPS12 | ribosomal protein S12 | 0.0145782 |
| RPS27 | ribosomal protein S27 | 0.0145259 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0144072 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0141672 |
| RPL11 | ribosomal protein L11 | 0.0140552 |
| RPL37 | ribosomal protein L37 | 0.0139951 |
| RPL5 | ribosomal protein L5 | 0.0139924 |
| GLYAT | glycine-N-acyltransferase | 0.0139666 |
| RPS19 | ribosomal protein S19 | 0.0138723 |
| FAM13A | family with sequence similarity 13, member A | 0.0137783 |
| FTL | ferritin, light polypeptide | 0.0137022 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0135777 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | 0.0135056 |
| DSPP | dentin sialophosphoprotein | 0.0133248 |
| RPS13 | ribosomal protein S13 | 0.0133008 |
| RPL31 | ribosomal protein L31 | 0.0131687 |
| SRP54 | signal recognition particle 54kDa | 0.0131408 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.013098 |
| ZFR | zinc finger RNA binding protein | 0.0130718 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0129934 |
| RPL32 | ribosomal protein L32 | 0.0129794 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0128786 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0128446 |
| FAM162A | family with sequence similarity 162, member A | 0.0126134 |
| RPL38 | ribosomal protein L38 | 0.0125951 |
| HDGF | hepatoma-derived growth factor | 0.0125646 |
| CALR | calreticulin | 0.0125624 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0125119 |
| S100A9 | S100 calcium binding protein A9 | 0.0125061 |
| NUP58 | nucleoporin 58 | 0.0124484 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0124042 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0123902 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0123772 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0123168 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0122597 |
| TUBB | tubulin, beta class I | 0.0122395 |
| TMSB10 | thymosin beta 10 | 0.012209 |
| RPL19 | ribosomal protein L19 | 0.0121308 |
| RPS3 | ribosomal protein S3 | 0.0120878 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0120364 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0119373 |
| ARRDC3 | arrestin domain containing 3 | 0.0118162 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.011787 |
| TUBA1C | tubulin, alpha 1c | 0.0117333 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0115307 |
| RPL35A | ribosomal protein L35a | 0.0114936 |
| TMF1 | TATA element modulatory factor 1 | 0.0114835 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0114418 |
| KRT6A | keratin 6A, type II | 0.0113794 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0113428 |
| RPS14 | ribosomal protein S14 | 0.0113 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0112343 |
| KIF5B | kinesin family member 5B | 0.0111702 |
| RPS16 | ribosomal protein S16 | 0.0109109 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0108945 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0108705 |
| S100A2 | S100 calcium binding protein A2 | 0.0108056 |
| SFXN1 | sideroflexin 1 | 0.0107649 |
| RPL36 | ribosomal protein L36 | 0.0106499 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0106221 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.273123 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.174991 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.151007 |
| LMO7 | LIM domain 7 | -0.123685 |
| PDLIM5 | PDZ and LIM domain 5 | -0.115752 |
| AHNAK | AHNAK nucleoprotein | -0.107483 |
| DPYD | dihydropyrimidine dehydrogenase | -0.104296 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.101027 |
| CD44 | CD44 molecule (Indian blood group) | -0.100655 |
| MTSS1 | metastasis suppressor 1 | -0.0957139 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0906756 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0870468 |
| MYOF | myoferlin | -0.0825399 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0806334 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0784257 |
| INTS6 | integrator complex subunit 6 | -0.0748811 |
| RIGI | RNA sensor RIG-I | -0.0710025 |
| RASAL2 | RAS protein activator like 2 | -0.0685754 |
| ACTN4 | actinin, alpha 4 | -0.0662514 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0660325 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0653812 |
| VCL | vinculin | -0.06374 |
| LDHA | lactate dehydrogenase A | -0.0634464 |
| SULF1 | sulfatase 1 | -0.061162 |
| ASPH | aspartate beta-hydroxylase | -0.0579641 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0574602 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0566466 |
| FOXO1 | forkhead box O1 | -0.0557786 |
| POTEF | POTE ankyrin domain family, member F | -0.0538207 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0523646 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0521222 |
| HMGA2 | high mobility group AT-hook 2 | -0.0519358 |
| PLS3 | plastin 3 | -0.0517388 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0511856 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0511652 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0502716 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0501096 |
| SULF2 | sulfatase 2 | -0.0500911 |
| CDK6 | cyclin-dependent kinase 6 | -0.0489698 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0489579 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0482244 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0479429 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0476032 |
| EMP1 | epithelial membrane protein 1 | -0.0473805 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0467712 |
| RAD51B | RAD51 paralog B | -0.0456849 |
| MSN | moesin | -0.044705 |
| PRSS23 | protease, serine, 23 | -0.0445403 |
| MECOM | MDS1 and EVI1 complex locus | -0.0442673 |
| SMAD3 | SMAD family member 3 | -0.0439813 |
| FN1 | fibronectin 1 | -0.0435687 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0433056 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0429987 |
| EFNA5 | ephrin-A5 | -0.0425539 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0419641 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0414981 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0413532 |
| LAMC2 | laminin, gamma 2 | -0.0410931 |
| NDRG1 | N-myc downstream regulated 1 | -0.0406665 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0405241 |
| UBC | ubiquitin C | -0.0404572 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0400992 |
| PALLD | palladin, cytoskeletal associated protein | -0.0398938 |
| JMJD1C | jumonji domain containing 1C | -0.0393089 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0391502 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0376346 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0374846 |
| SMYD3 | SET and MYND domain containing 3 | -0.0372372 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0372041 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0369915 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0366683 |
| PODXL | podocalyxin-like | -0.0362243 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0362081 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0359737 |
| UTRN | utrophin | -0.0356536 |
| EZR | ezrin | -0.0351025 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0350963 |
| ANXA1 | annexin A1 | -0.0348035 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0341656 |
| MCL1 | myeloid cell leukemia 1 | -0.0339309 |
| CLIC4 | chloride intracellular channel 4 | -0.0337388 |
| KIAA1671 | KIAA1671 | -0.0335301 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0334986 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0333028 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.032969 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0328687 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0324321 |
| DOK5 | docking protein 5 | -0.0318307 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0318067 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0307228 |
| IFI44 | interferon-induced protein 44 | -0.0305501 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0305145 |
| B2M | beta-2-microglobulin | -0.0304595 |
| DIAPH1 | diaphanous-related formin 1 | -0.0303311 |
| DGKH | diacylglycerol kinase, eta | -0.030279 |
| PRELID2 | PRELI domain containing 2 | -0.030244 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0301899 |
| PLXNA2 | plexin A2 | -0.0301824 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0300504 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0299537 |
