| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.0787458 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0749976 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0453164 |
| ATP13A3 | ATPase type 13A3 | 0.0402648 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0377502 |
| FTL | ferritin, light polypeptide | 0.0366559 |
| CCNL1 | cyclin L1 | 0.0355383 |
| FOSL1 | FOS-like antigen 1 | 0.0347325 |
| TPX2 | TPX2, microtubule-associated | 0.0319499 |
| MKI67 | marker of proliferation Ki-67 | 0.0314947 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.03014 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0296121 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0268287 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0263676 |
| PCBP2 | poly(rC) binding protein 2 | 0.026172 |
| NCKAP1 | NCK-associated protein 1 | 0.0251754 |
| CENPF | centromere protein F, 350/400kDa | 0.0239949 |
| NUP58 | nucleoporin 58 | 0.0237629 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0236119 |
| GOLGA4 | golgin A4 | 0.0234567 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0219659 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0216868 |
| SET | SET nuclear proto-oncogene | 0.0211064 |
| FNBP4 | formin binding protein 4 | 0.0210957 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0205966 |
| NOP58 | NOP58 ribonucleoprotein | 0.020168 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0199571 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0196922 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0195815 |
| B2M | beta-2-microglobulin | 0.0195582 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0190556 |
| GATA2 | GATA binding protein 2 | 0.0190087 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0189691 |
| TFG | TRK-fused gene | 0.0188658 |
| BCL2L1 | BCL2-like 1 | 0.0186152 |
| ENAH | enabled homolog (Drosophila) | 0.0185626 |
| FAR1 | fatty acyl CoA reductase 1 | 0.0185615 |
| ECT2 | epithelial cell transforming 2 | 0.0184735 |
| PRPF4B | pre-mRNA processing factor 4B | 0.0184365 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0183376 |
| TPD52 | tumor protein D52 | 0.0182354 |
| ZNF292 | zinc finger protein 292 | 0.0181712 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0181388 |
| ARF4 | ADP-ribosylation factor 4 | 0.0181182 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0178313 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0176183 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0175817 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0175163 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0173876 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0173366 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0171466 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0171222 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0169665 |
| DENND4C | DENN/MADD domain containing 4C | 0.0169299 |
| ZNF148 | zinc finger protein 148 | 0.0167142 |
| OLA1 | Obg-like ATPase 1 | 0.0165597 |
| PLK2 | polo-like kinase 2 | 0.0164713 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0163802 |
| H1-4 | H1.4 linker histone, cluster member | 0.0161238 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0160418 |
| RAB18 | RAB18, member RAS oncogene family | 0.0159681 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0159146 |
| TSC22D2 | TSC22 domain family, member 2 | 0.015601 |
| PNN | pinin, desmosome associated protein | 0.0155868 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0155601 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0154428 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0154357 |
| SPAG9 | sperm associated antigen 9 | 0.0153801 |
| LMO7 | LIM domain 7 | 0.0153318 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.015325 |
| RBM25 | RNA binding motif protein 25 | 0.0152647 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.015207 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0151589 |
| YBX1 | Y box binding protein 1 | 0.0151473 |
| ADM | adrenomedullin | 0.0149855 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0148975 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0148535 |
| SLTM | SAFB-like, transcription modulator | 0.0146909 |
| NUP153 | nucleoporin 153kDa | 0.0146721 |
| UFM1 | ubiquitin-fold modifier 1 | 0.0145761 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0144079 |
| PDS5B | PDS5 cohesin associated factor B | 0.014372 |
| WDR43 | WD repeat domain 43 | 0.0142228 |
| TGFB2 | transforming growth factor, beta 2 | 0.014177 |
| CCDC14 | coiled-coil domain containing 14 | 0.0140822 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0140606 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0140226 |
| AXL | AXL receptor tyrosine kinase | 0.0139692 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0138246 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0137618 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0133385 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0131888 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0131808 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.013136 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0130771 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0129895 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0129775 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0129688 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0129633 |
| AGFG1 | ArfGAP with FG repeats 1 | 0.012866 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.381426 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.233905 |
| EXT1 | exostosin glycosyltransferase 1 | -0.212541 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.178942 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.158421 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.158345 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.142898 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.112755 |
| NDRG1 | N-myc downstream regulated 1 | -0.108839 |
| HLA-B | major histocompatibility complex, class I, B | -0.0967423 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.095799 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0925065 |
| AHNAK | AHNAK nucleoprotein | -0.0924005 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0893576 |
| ASPH | aspartate beta-hydroxylase | -0.0880953 |
| INTS6 | integrator complex subunit 6 | -0.082209 |
| ANXA2 | annexin A2 | -0.0788117 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0757918 |
| RAI14 | retinoic acid induced 14 | -0.0723961 |
| MT2A | metallothionein 2A | -0.0701198 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0664952 |
| DTNA | dystrobrevin, alpha | -0.0657776 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0641747 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.064089 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0634212 |
| ERBIN | erbb2 interacting protein | -0.0632431 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0624155 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0617749 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0557259 |
| ACTG1 | actin gamma 1 | -0.0547111 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0542717 |
| GLIS3 | GLIS family zinc finger 3 | -0.0537506 |
| VIM | vimentin | -0.0537027 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0523657 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | -0.0516629 |
| VCL | vinculin | -0.0512129 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.050797 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0496751 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0491054 |
| TLE4 | transducin-like enhancer of split 4 | -0.0481455 |
| LDHA | lactate dehydrogenase A | -0.0468416 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0465129 |
| PRELID2 | PRELI domain containing 2 | -0.0462573 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0462572 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0451435 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0444668 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.044434 |
| CAVIN1 | caveolae associated protein 1 | -0.0429308 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0426404 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0402323 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.039587 |
| COL5A1 | collagen, type V, alpha 1 | -0.039517 |
| NAV2 | neuron navigator 2 | -0.0387312 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0387035 |
| PGK1 | phosphoglycerate kinase 1 | -0.0379059 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0378089 |
| SBF2 | SET binding factor 2 | -0.037325 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0370589 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0369283 |
| ENO1 | enolase 1, (alpha) | -0.0368491 |
| SMYD3 | SET and MYND domain containing 3 | -0.0365408 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0365084 |
| EGFR | epidermal growth factor receptor | -0.0355828 |
| CLIC4 | chloride intracellular channel 4 | -0.035239 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0351823 |
| NAV1 | neuron navigator 1 | -0.0351237 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0350706 |
| ZNF432 | zinc finger protein 432 | -0.0349664 |
| CAST | calpastatin | -0.0346724 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0346219 |
| DST | dystonin | -0.0344645 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0334166 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0333839 |
| DENND1A | DENN/MADD domain containing 1A | -0.0330108 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0324034 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0321177 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.031888 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.03184 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0318379 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0314097 |
| RPL35A | ribosomal protein L35a | -0.0314013 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0312982 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0310576 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0308139 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0307087 |
| STK4 | serine/threonine kinase 4 | -0.0306936 |
| CD44 | CD44 molecule (Indian blood group) | -0.0302746 |
| RIGI | RNA sensor RIG-I | -0.0301205 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0295896 |
| FLNB | filamin B, beta | -0.0295074 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0293689 |
| TMSB10 | thymosin beta 10 | -0.029312 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0289875 |
| CUX1 | cut-like homeobox 1 | -0.0289092 |
| KLF12 | Kruppel-like factor 12 | -0.0285194 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) | -0.0274763 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0272541 |
| LOX | lysyl oxidase | -0.0271921 |
| AEBP2 | AE binding protein 2 | -0.0271284 |
| WNT5B | wingless-type MMTV integration site family, member 5B | -0.0270335 |
