| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.260259 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0780372 |
| FTL | ferritin, light polypeptide | 0.0774781 |
| NUP58 | nucleoporin 58 | 0.0741835 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0729187 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0660346 |
| ZNF292 | zinc finger protein 292 | 0.0480367 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0462561 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0442376 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0436543 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0433226 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0418181 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0413618 |
| RPL23 | ribosomal protein L23 | 0.0412398 |
| QKI | QKI, KH domain containing, RNA binding | 0.0411525 |
| GOLGA4 | golgin A4 | 0.0406077 |
| RPLP2 | ribosomal protein, large, P2 | 0.0398227 |
| UBC | ubiquitin C | 0.0390396 |
| SPAG9 | sperm associated antigen 9 | 0.0389304 |
| NCKAP1 | NCK-associated protein 1 | 0.0370908 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.036716 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0366058 |
| RPS12 | ribosomal protein S12 | 0.0337842 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0334747 |
| RTN4 | reticulon 4 | 0.0322544 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0321938 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0320054 |
| RPS3 | ribosomal protein S3 | 0.0318816 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0318533 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0317215 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0317056 |
| RPS25 | ribosomal protein S25 | 0.0309855 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0307796 |
| RPL5 | ribosomal protein L5 | 0.0306094 |
| RPL19 | ribosomal protein L19 | 0.030541 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.030529 |
| RPS17 | ribosomal protein S17 | 0.0302773 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0302278 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.030208 |
| PTMA | prothymosin, alpha | 0.0301218 |
| RPL21 | ribosomal protein L21 | 0.0293946 |
| CUL3 | cullin 3 | 0.0293735 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0290459 |
| WDR43 | WD repeat domain 43 | 0.0287222 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0284584 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0284206 |
| CCNL1 | cyclin L1 | 0.0283551 |
| KIF5B | kinesin family member 5B | 0.0283345 |
| ATP13A3 | ATPase type 13A3 | 0.0283213 |
| BRD2 | bromodomain containing 2 | 0.0282679 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0279237 |
| RPL12 | ribosomal protein L12 | 0.0274341 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0272209 |
| RYBP | RING1 and YY1 binding protein | 0.0267873 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0263254 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0261448 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0260183 |
| PLK2 | polo-like kinase 2 | 0.0257886 |
| YBX3 | Y box binding protein 3 | 0.025766 |
| TFG | TRK-fused gene | 0.0255712 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0254448 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0252828 |
| NEK7 | NIMA-related kinase 7 | 0.0252416 |
| RBM39 | RNA binding motif protein 39 | 0.0251731 |
| MED13L | mediator complex subunit 13-like | 0.0249316 |
| PHIP | pleckstrin homology domain interacting protein | 0.0248124 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0247765 |
| ADM | adrenomedullin | 0.0244928 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.024459 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0240601 |
| HELZ | helicase with zinc finger | 0.0240587 |
| CASC3 | cancer susceptibility candidate 3 | 0.0237527 |
| TUBA1B | tubulin, alpha 1b | 0.0237176 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0235913 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0234738 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0232319 |
| CDC73 | cell division cycle 73 | 0.0231064 |
| TFRC | transferrin receptor | 0.0229328 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0228331 |
| TPM3 | tropomyosin 3 | 0.0228246 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.022793 |
| RPS23 | ribosomal protein S23 | 0.022677 |
| RPL11 | ribosomal protein L11 | 0.0226683 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0226638 |
| YBX1 | Y box binding protein 1 | 0.0225835 |
| RLF | rearranged L-myc fusion | 0.0224934 |
| ZNF207 | zinc finger protein 207 | 0.0224243 |
| PAPOLA | poly(A) polymerase alpha | 0.0223699 |
| ZC3H15 | zinc finger CCCH-type containing 15 | 0.0222928 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0222301 |
| ERBIN | erbb2 interacting protein | 0.0221978 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0221687 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0221585 |
| RPL3 | ribosomal protein L3 | 0.0221301 |
| USP15 | ubiquitin specific peptidase 15 | 0.021767 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0217036 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0216466 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0215852 |
| MATR3 | matrin 3 | 0.0215752 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0215558 |
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.337671 |
| VIM | vimentin | -0.213824 |
| EFNA5 | ephrin-A5 | -0.196778 |
| EXT1 | exostosin glycosyltransferase 1 | -0.186314 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.160598 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.126664 |
| MMP12 | matrix metallopeptidase 12 | -0.109533 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.103551 |
| LSAMP | limbic system-associated membrane protein | -0.102976 |
| KIAA1549L | KIAA1549-like | -0.0955067 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0949353 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0926017 |
| CDH13 | cadherin 13 | -0.0880377 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0851345 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0848113 |
| GPC6 | glypican 6 | -0.0830894 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.081873 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0796848 |
| NAV1 | neuron navigator 1 | -0.0754131 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.072394 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0647562 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0636057 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.062766 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0625014 |
| NTM | neurotrimin | -0.0606909 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0603478 |
| ASPH | aspartate beta-hydroxylase | -0.0601337 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0589833 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0575161 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0568514 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0565098 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0551335 |
| KIAA1217 | KIAA1217 | -0.0523881 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.052303 |
| MYO10 | myosin X | -0.0521903 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0487583 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.048505 |
| PTK2 | protein tyrosine kinase 2 | -0.0462616 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0429125 |
| FOXP1 | forkhead box P1 | -0.0424779 |
| PRKCE | protein kinase C, epsilon | -0.041878 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0417655 |
| FMNL2 | formin-like 2 | -0.0417393 |
| RAD51B | RAD51 paralog B | -0.0411156 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0405355 |
| EGR1 | early growth response 1 | -0.0398973 |
| NDRG1 | N-myc downstream regulated 1 | -0.0385674 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0380586 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0380379 |
| RNF213 | ring finger protein 213 | -0.0377363 |
| ARHGAP18 | Rho GTPase activating protein 18 | -0.0372941 |
| SBF2 | SET binding factor 2 | -0.037054 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0360202 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0347635 |
| CDK6 | cyclin-dependent kinase 6 | -0.033965 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0337488 |
| FN1 | fibronectin 1 | -0.0329579 |
| ANO6 | anoctamin 6 | -0.0320167 |
| CUX1 | cut-like homeobox 1 | -0.0318542 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0317741 |
| DST | dystonin | -0.0316963 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0315572 |
| CD109 | CD109 molecule | -0.0311925 |
| RIGI | RNA sensor RIG-I | -0.0308902 |
| ITGA6 | integrin, alpha 6 | -0.0307879 |
| RUNX1 | runt-related transcription factor 1 | -0.0306628 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0306151 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0305041 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0304413 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0304296 |
| HMGA2 | high mobility group AT-hook 2 | -0.030211 |
| NRP2 | neuropilin 2 | -0.0300492 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0300336 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0293483 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0288646 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0286354 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0286033 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0284724 |
| VEPH1 | ventricular zone expressed PH domain-containing 1 | -0.0284607 |
| CALD1 | caldesmon 1 | -0.0282522 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0280878 |
| ANXA2 | annexin A2 | -0.0278909 |
| WWC1 | WW and C2 domain containing 1 | -0.0277583 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0275253 |
| TNNC1 | troponin C type 1 (slow) | -0.0274674 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0274292 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0272809 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.027209 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0270969 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0269539 |
| PCDH9 | protocadherin 9 | -0.0261374 |
| EGFR | epidermal growth factor receptor | -0.0258293 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0256358 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0254222 |
| KDM2B | lysine (K)-specific demethylase 2B | -0.0248323 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.024759 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0246889 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0242868 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0238014 |
| SSH2 | slingshot protein phosphatase 2 | -0.0237403 |
