| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.123295 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.120107 |
| RPS12 | ribosomal protein S12 | 0.114648 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.107995 |
| RPLP2 | ribosomal protein, large, P2 | 0.0840314 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0797658 |
| RPL37A | ribosomal protein L37a | 0.0712488 |
| RPS3 | ribosomal protein S3 | 0.0691857 |
| CALR | calreticulin | 0.0684586 |
| RPS17 | ribosomal protein S17 | 0.0601143 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0587667 |
| RPL3 | ribosomal protein L3 | 0.0565722 |
| EREG | epiregulin | 0.0561387 |
| RPS6 | ribosomal protein S6 | 0.05594 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0559294 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0542806 |
| TMSB4X | thymosin beta 4, X-linked | 0.0540999 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0492393 |
| FAM13A | family with sequence similarity 13, member A | 0.0488051 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0478523 |
| RPL23 | ribosomal protein L23 | 0.0473011 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0464427 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0409256 |
| RPS27A | ribosomal protein S27a | 0.0407413 |
| PNN | pinin, desmosome associated protein | 0.0405242 |
| RPL21 | ribosomal protein L21 | 0.0385503 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0378743 |
| MED13L | mediator complex subunit 13-like | 0.0372995 |
| RPL19 | ribosomal protein L19 | 0.0367279 |
| RPL5 | ribosomal protein L5 | 0.0344662 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0340564 |
| ZNF292 | zinc finger protein 292 | 0.0333417 |
| GOLGA4 | golgin A4 | 0.0330351 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0329885 |
| RPL26 | ribosomal protein L26 | 0.0329537 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0328994 |
| RPL36 | ribosomal protein L36 | 0.0324408 |
| RPS2 | ribosomal protein S2 | 0.0308391 |
| RPS25 | ribosomal protein S25 | 0.0305456 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0304704 |
| NUP58 | nucleoporin 58 | 0.0300721 |
| RPL12 | ribosomal protein L12 | 0.0291735 |
| NCKAP1 | NCK-associated protein 1 | 0.0289545 |
| CCNL1 | cyclin L1 | 0.0282613 |
| TPM3 | tropomyosin 3 | 0.0282529 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0281953 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0279758 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0276625 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0272764 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0271719 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0268716 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0264917 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.0264129 |
| TUBA1B | tubulin, alpha 1b | 0.0259188 |
| RPL38 | ribosomal protein L38 | 0.0255775 |
| HDGF | hepatoma-derived growth factor | 0.0255228 |
| RPS19 | ribosomal protein S19 | 0.0255084 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0250944 |
| H2AC6 | H2A clustered histone 6 | 0.0245369 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0244087 |
| PAPOLA | poly(A) polymerase alpha | 0.0243438 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0242897 |
| SET | SET nuclear proto-oncogene | 0.0242307 |
| CANX | calnexin | 0.0238944 |
| MKI67 | marker of proliferation Ki-67 | 0.0238688 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0237893 |
| VEGFA | vascular endothelial growth factor A | 0.023728 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0234597 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0234283 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0234073 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0232831 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0228506 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0227617 |
| RPS11 | ribosomal protein S11 | 0.0226211 |
| UBC | ubiquitin C | 0.0226145 |
| OGA | O-GlcNAcase | 0.0217408 |
| RPL31 | ribosomal protein L31 | 0.0216882 |
| PCM1 | pericentriolar material 1 | 0.0216078 |
| RPL36A | ribosomal protein L36a | 0.0215127 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.021473 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | 0.0214365 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0214177 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0212865 |
| PLEC | plectin | 0.0212444 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | 0.0211446 |
| CENPE | centromere protein E, 312kDa | 0.0211203 |
| NDRG1 | N-myc downstream regulated 1 | 0.0209789 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0207496 |
| RPS26 | ribosomal protein S26 | 0.0204972 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0204292 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0204228 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0201946 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0201004 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0199519 |
| RPL11 | ribosomal protein L11 | 0.019882 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0198602 |
| RPS3A | ribosomal protein S3A | 0.0195685 |
| RPL27 | ribosomal protein L27 | 0.0194507 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0193928 |
| TMF1 | TATA element modulatory factor 1 | 0.019215 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.218667 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.192025 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.149906 |
| MYO1E | myosin IE | -0.124613 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.11369 |
| EZR | ezrin | -0.107373 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0964792 |
| LDHA | lactate dehydrogenase A | -0.0911411 |
| NPSR1 | neuropeptide S receptor 1 | -0.0883482 |
| ANXA2 | annexin A2 | -0.0857352 |
| MT2A | metallothionein 2A | -0.0851017 |
| RPLP1 | ribosomal protein, large, P1 | -0.0837007 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0832252 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0753923 |
| LMO7 | LIM domain 7 | -0.0752692 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0743883 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0742361 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0739238 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0729614 |
| ITGA6 | integrin, alpha 6 | -0.0701403 |
| RPL35A | ribosomal protein L35a | -0.0691047 |
| HMGA1 | high mobility group AT-hook 1 | -0.0665959 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0627891 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0626392 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0607549 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0599862 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0586048 |
| ACTN4 | actinin, alpha 4 | -0.0564628 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0555962 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0526619 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0506723 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0505859 |
| CADPS | Ca++-dependent secretion activator | -0.0495946 |
| MED13 | mediator complex subunit 13 | -0.049137 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.048734 |
| PGK1 | phosphoglycerate kinase 1 | -0.0486121 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0471143 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0463048 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0446411 |
| KRT19 | keratin 19, type I | -0.0445488 |
| AHNAK | AHNAK nucleoprotein | -0.0444922 |
| TMSB10 | thymosin beta 10 | -0.0444612 |
| VCL | vinculin | -0.0444366 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0434998 |
| EMP1 | epithelial membrane protein 1 | -0.0429412 |
| S100P | S100 calcium binding protein P | -0.04249 |
| CCND1 | cyclin D1 | -0.0423156 |
| PERP | PERP, TP53 apoptosis effector | -0.0416656 |
| B2M | beta-2-microglobulin | -0.0414914 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0414426 |
| MUC17 | mucin 17, cell surface associated | -0.0413579 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0411551 |
| PTMA | prothymosin, alpha | -0.0408014 |
| ABLIM1 | actin binding LIM protein 1 | -0.0399364 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0391376 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0390367 |
| ANXA1 | annexin A1 | -0.0386807 |
| FOXO1 | forkhead box O1 | -0.0384746 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0382621 |
| LMNA | lamin A/C | -0.0378895 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0369162 |
| TXNIP | thioredoxin interacting protein | -0.036412 |
| POTEF | POTE ankyrin domain family, member F | -0.0358427 |
| KLF6 | Kruppel-like factor 6 | -0.0356821 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0354876 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0353939 |
| GPHN | gephyrin | -0.0353022 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0341977 |
| EGR1 | early growth response 1 | -0.0341676 |
| ATXN1 | ataxin 1 | -0.0339807 |
| MT1X | metallothionein 1X | -0.0339705 |
| ONECUT3 | one cut homeobox 3 | -0.0339234 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0338687 |
| FHL2 | four and a half LIM domains 2 | -0.0328177 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0327685 |
| LAMA4 | laminin, alpha 4 | -0.0321161 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0321097 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.031923 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0318434 |
| IER3 | immediate early response 3 | -0.0309024 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0308067 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0302564 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0298107 |
| RRBP1 | ribosome binding protein 1 | -0.0295701 |
| SMYD3 | SET and MYND domain containing 3 | -0.0294089 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0292549 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0290382 |
| RPL7 | ribosomal protein L7 | -0.0289552 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0288957 |
| DIAPH2 | diaphanous-related formin 2 | -0.0285823 |
| HMGB1 | high mobility group box 1 | -0.0285751 |
| JUN | jun proto-oncogene | -0.0284337 |
| SHROOM3 | shroom family member 3 | -0.0283843 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0283671 |
| TC2N | tandem C2 domains, nuclear | -0.0283565 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0280498 |
| RNF217 | ring finger protein 217 | -0.0280067 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0276261 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0275912 |
| PER2 | period circadian clock 2 | -0.027489 |
