| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Docetaxel (Trihydrate) perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Docetaxel (Trihydrate)_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.148364 |
| RPS12 | ribosomal protein S12 | 0.114294 |
| RPS3 | ribosomal protein S3 | 0.0729072 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0700394 |
| RPL21 | ribosomal protein L21 | 0.0649389 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0641755 |
| RPL3 | ribosomal protein L3 | 0.0568571 |
| GOLGA4 | golgin A4 | 0.0550271 |
| RPLP2 | ribosomal protein, large, P2 | 0.0547899 |
| CALB1 | calbindin 1, 28kDa | 0.0530824 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0499792 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0477993 |
| RPS17 | ribosomal protein S17 | 0.0430893 |
| FAT1 | FAT atypical cadherin 1 | 0.0425308 |
| MKI67 | marker of proliferation Ki-67 | 0.0420265 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.04154 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0414065 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.0399517 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0369532 |
| ITGA6 | integrin, alpha 6 | 0.0360146 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0352052 |
| ZNF292 | zinc finger protein 292 | 0.0319632 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.030404 |
| ABHD17C | abhydrolase domain containing 17C | 0.030337 |
| PNN | pinin, desmosome associated protein | 0.0289042 |
| RPL37A | ribosomal protein L37a | 0.0284327 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0272948 |
| PCBP2 | poly(rC) binding protein 2 | 0.0264165 |
| PTEN | phosphatase and tensin homolog | 0.0262902 |
| RPS6 | ribosomal protein S6 | 0.0262266 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0258843 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0258669 |
| PLAC8 | placenta-specific 8 | 0.0257687 |
| TXNRD1 | thioredoxin reductase 1 | 0.0253286 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0251299 |
| FLNB | filamin B, beta | 0.0248222 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0244108 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0242529 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0242112 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0238695 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0237717 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0229097 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0228681 |
| MLEC | malectin | 0.0227658 |
| TMF1 | TATA element modulatory factor 1 | 0.0227061 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0227046 |
| CDK19 | cyclin-dependent kinase 19 | 0.0221024 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0217981 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0215151 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0214946 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0214136 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0211959 |
| CENPF | centromere protein F, 350/400kDa | 0.0209494 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0207913 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0202753 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0199767 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.019813 |
| RPL23 | ribosomal protein L23 | 0.0197266 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.019533 |
| SLK | STE20-like kinase | 0.0195045 |
| RIN2 | Ras and Rab interactor 2 | 0.0194907 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0194592 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0193515 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0193431 |
| HDGF | hepatoma-derived growth factor | 0.019341 |
| FOXO1 | forkhead box O1 | 0.0193175 |
| RPL12 | ribosomal protein L12 | 0.0191999 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0190839 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0189115 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0187759 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | 0.0187164 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0186682 |
| SEM1 | SEM1 26S proteasome subunit | 0.018576 |
| LRRC1 | leucine rich repeat containing 1 | 0.0185728 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0185478 |
| TRIM31 | tripartite motif containing 31 | 0.0185092 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0184247 |
| NKTR | natural killer cell triggering receptor | 0.0183828 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0182762 |
| MYO6 | myosin VI | 0.0181777 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0180802 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0175475 |
| PRELID2 | PRELI domain containing 2 | 0.0174022 |
| TUBA1B | tubulin, alpha 1b | 0.0172877 |
| TRIM15 | tripartite motif containing 15 | 0.0172527 |
| RPL5 | ribosomal protein L5 | 0.0171812 |
| SLFN5 | schlafen family member 5 | 0.017161 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0170597 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0169096 |
| RPS27 | ribosomal protein S27 | 0.0168874 |
| XPC | xeroderma pigmentosum, complementation group C | 0.0167188 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0167183 |
| SLTM | SAFB-like, transcription modulator | 0.016568 |
| RPL13A | ribosomal protein L13a | 0.0165581 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0165446 |
| RPS11 | ribosomal protein S11 | 0.0162487 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0162168 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0162063 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0161868 |
| CCPG1 | cell cycle progression 1 | 0.0160973 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPLP1 | ribosomal protein, large, P1 | -0.234164 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.170573 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.169304 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.147061 |
| LMO7 | LIM domain 7 | -0.105941 |
| MYO1E | myosin IE | -0.102178 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.100032 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0954358 |
| ANXA2 | annexin A2 | -0.0776428 |
| RPL35A | ribosomal protein L35a | -0.0735033 |
| ACTG1 | actin gamma 1 | -0.0715177 |
| RPL34 | ribosomal protein L34 | -0.0703205 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0699106 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0689517 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0678223 |
| SERINC5 | serine incorporator 5 | -0.0676847 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0676067 |
| PKM | pyruvate kinase, muscle | -0.0649528 |
| LDHA | lactate dehydrogenase A | -0.064349 |
| KRT18 | keratin 18, type I | -0.0636572 |
| RPLP0 | ribosomal protein, large, P0 | -0.0616898 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.0607879 |
| EZR | ezrin | -0.0572566 |
| FBXO11 | F-box protein 11 | -0.0570575 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0565602 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0561973 |
| DSG2 | desmoglein 2 | -0.0555028 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0539522 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0525017 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0521655 |
| OXSR1 | oxidative stress responsive 1 | -0.0515915 |
| RPL4 | ribosomal protein L4 | -0.05091 |
| MSI2 | musashi RNA-binding protein 2 | -0.0504917 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0501273 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.046373 |
| LAMB3 | laminin, beta 3 | -0.0463719 |
| RPS24 | ribosomal protein S24 | -0.0456509 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.045385 |
| TC2N | tandem C2 domains, nuclear | -0.0449195 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0448554 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0437743 |
| CANX | calnexin | -0.0433004 |
| CTBP2 | C-terminal binding protein 2 | -0.0428757 |
| CUX1 | cut-like homeobox 1 | -0.0427584 |
| FRMD5 | FERM domain containing 5 | -0.0426276 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0421916 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0415599 |
| RPL7 | ribosomal protein L7 | -0.0408266 |
| CCND2 | cyclin D2 | -0.0407412 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0403706 |
| PGK1 | phosphoglycerate kinase 1 | -0.0396057 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.039586 |
| TSPAN8 | tetraspanin 8 | -0.0381126 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0379351 |
| INTS6 | integrator complex subunit 6 | -0.0377175 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0375755 |
| S100P | S100 calcium binding protein P | -0.0375604 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0366898 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0363687 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.0362619 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0353031 |
| LRRC23 | leucine rich repeat containing 23 | -0.0351795 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0350247 |
| PALLD | palladin, cytoskeletal associated protein | -0.0344617 |
| SPINK13 | serine peptidase inhibitor, Kazal type 13 (putative) | -0.0343783 |
| S100A10 | S100 calcium binding protein A10 | -0.0343136 |
| NPR2 | natriuretic peptide receptor 2 | -0.0342602 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0342549 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0338726 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0336018 |
| RPS8 | ribosomal protein S8 | -0.033595 |
| ACTN4 | actinin, alpha 4 | -0.0335301 |
| IRF1 | interferon regulatory factor 1 | -0.0333641 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0329885 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0326201 |
| HDLBP | high density lipoprotein binding protein | -0.0324417 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0319668 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0315521 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0314394 |
| ARF1 | ADP-ribosylation factor 1 | -0.0310029 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0309313 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0307961 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0305745 |
| MYO5B | myosin VB | -0.030517 |
| RRBP1 | ribosome binding protein 1 | -0.0303874 |
| FUS | FUS RNA binding protein | -0.0302978 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0298281 |
| RPL27A | ribosomal protein L27a | -0.0297726 |
| SQSTM1 | sequestosome 1 | -0.0295438 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0294727 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0294462 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0293591 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0292558 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0288076 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0286247 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0283549 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0283399 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0283025 |
| AHNAK | AHNAK nucleoprotein | -0.0282966 |
| FOXO3 | forkhead box O3 | -0.0282616 |
